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Published on in Vol 9 (2026)

Preprints (earlier versions) of this paper are available at https://preprints.jmir.org/preprint/93011, first published .
Doctor discusses brain health with older women; one shows confusion, the other contemplation.

Large Language Model–Based Identification of Subjective Cognitive Decline in Electronic Health Records Among Older Adults With Normal Cognitive Testing: Retrospective Cohort Study

Large Language Model–Based Identification of Subjective Cognitive Decline in Electronic Health Records Among Older Adults With Normal Cognitive Testing: Retrospective Cohort Study

Liqin Wang   1, 2 , PhD ;   Rebecca E Amariglio   2, 3 , PhD ;   Sheril Varghese   1, 4 , BA ;   Jiazi Tian   5 , MS ;   Diane Seger   6 , RPh ;   Li Zhou   1, 2 , MD, PhD ;   Gad A Marshall   2, 3 , MD

1 Department of Medicine, Mass General Brigham, Somerville, MA, United States

2 Harvard Medical School, Boston, MA, United States

3 Department of Neurology, Mass General Brigham, Boston, MA, United States

4 Columbia University Irving Medical Center, New York, NY, United States

5 Department of Medicine, Massachusetts General Hospital, Boston, MA, United States

6 Research Information Science & Computing, Mass General Brigham, Boston, MA, United States

Corresponding Author:

  • Liqin Wang, PhD
  • Department of Medicine
  • Mass General Brigham
  • 399 Revolution Drive
  • Somerville, MA 02145
  • United States
  • Phone: 857-282-4089
  • Email: lwang@bwh.harvard.edu