Examining Associations Between Smartphone Use and Clinical Severity in Frontotemporal Dementia: Proof-of-Concept Study

Emily W Paolillo   ¹ , PhD ;   Kaitlin B Casaletto   ¹ , PhD ;   Annie L Clark   ¹ , MS ;   Jack C Taylor   ¹ , MAS ;   Hilary W Heuer   ¹ , PhD ;   Amy B Wise   ¹ , BS ;   Sreya Dhanam   ¹ , BS ;   Mark Sanderson-Cimino   ¹ , PhD ;   Rowan Saloner   ¹ , PhD ;   Joel H Kramer   ¹ , PsyD ;   John Kornak   ² , PhD ;   Walter Kremers   ³ , PhD ;   Leah Forsberg   ⁴ , PhD ;   Brian Appleby   ⁵ , MD ;   Ece Bayram   ⁶ , MD, PhD ;   Andrea Bozoki   ⁷ , MD ;   Danielle Brushaber   ³ , BS ;   R Ryan Darby   ⁸ , MD ;   Gregory S Day   ⁹ , MSc, MD ;   Bradford C Dickerson   ¹⁰ , MD ;   Kimiko Domoto-Reilly   ¹¹ , MS, MD ;   Fanny Elahi   ^{12, 13} , MD, PhD ;   Julie A Fields   ¹⁴ , PhD ;   Nupur Ghoshal   ¹⁵ , MD, PhD ;   Neill Graff-Radford   ⁹ , MD ;   Matthew G H Hall   ¹ , MS ;   Lawrence S Honig   ¹⁶ , MD ;   Edward D Huey   ¹⁷ , MD ;   Maria I Lapid   ¹⁴ , MD ;   Irene Litvan   ⁶ , MD ;   Ian R Mackenzie   ¹⁸ , MD ;   Joseph C Masdeu   ¹⁹ , MD, PhD ;   Mario F Mendez   ²⁰ , MD, PhD ;   Carly Mester   ³ , BA ;   Toji Miyagawa   ⁴ , MD, PhD ;   Georges Naasan   ²¹ , MD ;   Belen Pascual   ¹⁹ , PhD ;   Peter Pressman   ²² , MD ;   Eliana Marisa Ramos   ²⁰ , PhD ;   Katherine P Rankin   ¹ , PhD ;   Jessica Rexach   ²⁰ , MD, PhD ;   Julio C Rojas   ¹ , MD, PhD ;   Lawren VandeVrede   ¹ , MD, PhD ;   Bonnie Wong   ²³ , PhD ;   Zbigniew K Wszolek   ⁹ , MD ;   Bradley F Boeve   ⁴ , MD ;   Howard J Rosen   ¹ , MD ;   Adam L Boxer   ¹ , MD, PhD ;   Adam M Staffaroni   ¹ , PhD ;   ALLFTD Consortium   ²⁴

¹ Department of Neurology, Memory and Aging Center, Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, United States

² Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, United States

³ Department of Quantitative Health Sciences, Division of Clinical Trials and Biostatistics, Mayo Clinic, Rochester, MN, United States

⁴ Department of Neurology, Mayo Clinic, Rochester, MN, United States

⁵ Department of Neurology, Case Western Reserve University, Cleveland, OH, United States

⁶ Department of Neurosciences, University of California, San Diego, La Jolla, CA, United States

⁷ Department of Neurology, University of North Carolina, Chapel Hill, NC, United States

⁸ Department of Neurology, Vanderbilt University, Nashville, TN, United States

⁹ Department of Neurology, Mayo Clinic, Jacksonville, FL, United States

¹⁰ Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, United States

¹¹ Department of Neurology, University of Washington, Seattle, WA, United States

¹² Department of Neurology, The Deane Center for Wellness and Cognitive Health, Icahn School of Medicine at Mount Sinai, New York, NY, United States

¹³ James J. Peters Veterans Affairs Medical Center, New York, NY, United States

¹⁴ Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN, United States

¹⁵ Department of Neurology, Knight Alzheimer's Disease Research Center, Washington University, St. Louis, MO, United States

¹⁶ Department of Neurology, Columbia University, New York, NY, United States

¹⁷ Department of Psychiatry and Human Behavior, Brown University, Providence, RI, United States

¹⁸ Department of Pathology, University of British Columbia, Vancouver, BC, Canada

¹⁹ Stanley H. Appel Department of Neurology, Nantz National Alzheimer Center, Houston Methodist Research Institute, Weill Cornell Medicine, Houston, TX, United States

²⁰ Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, United States

²¹ Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY, United States

²² Department of Neurology, University of Colorado, Aurora, CO, United States

²³ Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Boston, MA, United States

²⁴ see Acknowledgements, San Francisco, CA, United States