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Frailty is associated with adverse health outcomes and increased dependency, severely increasing the risk of early mortality in older adults [1]. In long-term care (LTC) facilities, approximately 52.3% of older adults are affected by frailty [2], posing a significant threat to residents’ well-being and sustainability in health care. Effective and efficient frailty screening methods are urgently needed to mitigate these negative outcomes and the progression of frailty among older adults in LTC facilities.
JMIR Aging 2025;8:e77140
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To develop data-driven approaches for deploying telemedicine that improve access to care among complex older adults with frailty, it is essential to understand what proportion can successfully complete video visits and to identify the factors associated with their successful use.
The primary aim of this study was to evaluate the proportion of older adults with frailty who were able to complete a video visit for receiving health care.
J Med Internet Res 2025;27:e69437
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Frailty prevalence, reported in 11 (78.6%) studies, varied substantially by cancer type and assessment method: lowest in lung cancer cohorts using the Frailty Index based on Laboratory test data (4.9%) and highest in a mixed malignancy study involving the clinical frailty scale (67.3%).
Through the systematic screening of 14 studies, we identified 23 frailty-associated factors appearing in 2 or more studies.
JMIR Cancer 2025;11:e69936
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These factors reflect multidimensional contributions from psychosocial states, physical frailty markers, systemic inflammation, and biomechanical stressors. Notably, participants with a history of disability, chronic diseases, or falls exhibited significantly higher ADL dysfunction risk, consistent with previous evidence on functional decline pathways [14,15]. The 2.5-m walking time defined in this study is negatively correlated with gait speed.
JMIR Med Inform 2025;13:e73030
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Frailty affects various aspects of older adults’ lives, including gait, mobility, balance, muscle strength, motor processing, cognition, nutrition, endurance, and physical activity (PA) [4]. Importantly, high levels of frailty increase the risks of adverse health outcomes such as falls, hospitalization, and mortality [5].
Frailty is a modifiable, dynamic process characterized by frequent transitions between different frailty states over time.
JMIR Mhealth Uhealth 2025;13:e69259
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Furthermore, all the aforementioned PD symptoms seem to relate to the reduction of physical activity, muscle mass, and strength levels, as well as movement performance of patients with PD, thus increasing sarcopenia and frailty [2-4]. It is well accepted that systematic physical exercise enhances neuroplasticity [5]; prevents or delays frailty [4,6]; and improves symptoms such as balance, gait, and Qo L in people with PD [7].
JMIR Res Protoc 2025;14:e65490
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Physical frailty and cognitive impairment are prevalent among older adults and have individually been associated with adverse health outcomes [1,2]. They often coincide with aging and can be bidirectionally linked to each other [3,4], prompting the introduction of the concept of cognitive frailty—the coexistence of both physical frailty and cognitive impairment [5].
JMIR Aging 2025;8:e65183
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In “Machine Learning Models for Frailty Classification of Older Adults in Northern Thailand: Model Development and Validation Study” (JMIR Aging 2025;8:e62942) one error was noted.
Reference 44 was a duplicate of reference 36, which reads as follows:
Thinuan P, Siviroj P, Lerttrakarnnon P, Lorga T. Prevalence and potential predictors of frailty among community-dwelling older persons in northern Thailand: a cross-sectional study. Int J Environ Res Public Health. Jun 8, 2020;17(11):4077.
JMIR Aging 2025;8:e75690
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The co-occurrence of frailty and early-stage cognitive decline has been well documented, with studies showing an increased likelihood of frailty in older adults with SCD or MCI. Two systematic reviews and meta-analyses have offered solid evidence of this relationship [15,16].
JMIR Mhealth Uhealth 2025;13:e64853
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Recent evidence underscores the impact of neighborhood characteristics on frailty among older people. Those residing in neighborhoods with abundant green spaces exhibit a lower incidence of frailty, whereas individuals perceiving precarious conditions in their surroundings, houses, and environment face a higher risk of frailty [19-21].
JMIR Aging 2025;8:e64254
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