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The Digital Therapeutics Real-World Evidence Framework: An Approach for Guiding Evidence-Based Digital Therapeutics Design, Development, Testing, and Monitoring

The Digital Therapeutics Real-World Evidence Framework: An Approach for Guiding Evidence-Based Digital Therapeutics Design, Development, Testing, and Monitoring

The aspiration is that DTx can improve a patient’s health outcomes, reduce the burden on health care professionals, and increase access to and usability of interventions [1,5], by providing safe, effective, and equitable support for individual and population health [6]. While myriad frameworks exist for DTx development, to date, no single unifying framework guides DTx evidence production and regulatory decision-making [7-11].

Meelim Kim, Kevin Patrick, Camille Nebeker, Job Godino, Spencer Stein, Predrag Klasnja, Olga Perski, Clare Viglione, Aaron Coleman, Eric Hekler

J Med Internet Res 2024;26:e49208

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Acceptability of a Hypothetical Reduction in Routinely Scheduled Clinic Visits Among Patients With History of a Localized Melanoma (MEL-SELF): Pilot Randomized Clinical Trial

Acceptability of a Hypothetical Reduction in Routinely Scheduled Clinic Visits Among Patients With History of a Localized Melanoma (MEL-SELF): Pilot Randomized Clinical Trial

But if technology is good, maybe no scheduled checks, then.” (070_control_baseline) “With the digital technology I am a little more confident of picking up a melanoma early.” (011_intervention_6months) Advice from the patient’s treating doctor that a reduction in visits was safe and that they were suitable for patient-led surveillance “Due to the quantity of moles I have, I find regular personal checking and doctor checking helpful for my treatment, I am also willing to use the mole scope process to reduce doctor

Dorothy Drabarek, Deonna Ackermann, Ellie Medcalf, Katy J L Bell

JMIR Dermatol 2023;6:e45865

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Prevalence of Antibiotic-Resistant Bacteria and Antibiotic-Resistant Genes and the Quantification of Antibiotics in Drinking Water Treatment Plants of Malaysia: Protocol for a Cross-sectional Study

Prevalence of Antibiotic-Resistant Bacteria and Antibiotic-Resistant Genes and the Quantification of Antibiotics in Drinking Water Treatment Plants of Malaysia: Protocol for a Cross-sectional Study

Access to clean and safe water is of the utmost importance worldwide. For general well-being, human beings use water for daily consumption and hygiene purposes. Water also serves as an important factor for maintaining a sustainable environment and plays an important role in climate change issues. Unfortunately, environmental water also plays a prominent role in the spread of antibiotic-resistant genes (ARGs) and antibiotic-resistant bacteria (ARB).

Zuraifah Asrah Mohamad, Sophia Karen Bakon, Mohd Azerulazree Jamilan Jamilan, Norhafizan Daud, Lena Ciric, Norazah Ahmad, Nor Asiah Muhamad

JMIR Res Protoc 2022;11(11):e37663

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