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Longitudinal Digital Phenotyping of Multiple Sclerosis Severity Using Passively Sensed Behaviors and Ecological Momentary Assessments: Real-World Evaluation

Longitudinal Digital Phenotyping of Multiple Sclerosis Severity Using Passively Sensed Behaviors and Ecological Momentary Assessments: Real-World Evaluation

Multiple sclerosis (MS) is a leading cause of chronic neurological disability, affecting around 2.8 million people worldwide and >700,000 people in the United States, while causing high health and socioeconomic burdens [1-3]. People with MS may experience a variety of neurological symptoms involving the cognitive, motor, sensory, vision, bowel, or bladder domains, as well as symptoms of depression, fatigue, and sleep disturbance in their daily lives [4].

Zongqi Xia, Prerna Chikersal, Shruthi Venkatesh, Elizabeth Walker, Anind K Dey, Mayank Goel

J Med Internet Res 2025;27:e70871

Factors Related to Pain and Disability Outcomes After an Internet-Delivered or Physiotherapist-Led Exercise Program for Individuals With Chronic Whiplash Symptoms: Secondary Analysis of a Randomized Controlled Study

Factors Related to Pain and Disability Outcomes After an Internet-Delivered or Physiotherapist-Led Exercise Program for Individuals With Chronic Whiplash Symptoms: Secondary Analysis of a Randomized Controlled Study

Consequently, there is a need to identify factors related to improvement in disability and pain in order to optimize treatment, discriminating them from factors that may contribute to sustained problems. An earlier study found that depression, low self-efficacy, and higher disability were associated with a larger pain area in women with chronic WAD [10].

Gunnel Peterson, Stefan Ljunggren, Anneli Peolsson

JMIR Hum Factors 2025;12:e67991

Evidence of Interventions for the Prevention of Unintentional Injuries: Scoping Review

Evidence of Interventions for the Prevention of Unintentional Injuries: Scoping Review

In addition to mortality risk, unintentional injuries can result in significant disability and disruption to quality of life [2,3]. Unfortunately, over 95% of all child injury deaths occur in low- and middle-income countries, resulting in a highly inequitable burden [4]. In India alone, unintentional injuries contribute to 9.1 deaths per 100,000 population, while transport injuries account for 2.8 deaths per 100,000 population [5].

Sheela Shetty, Baby S Nayak, Anice George, Avinash Shetty, Vasudeva Guddattu

JMIR Pediatr Parent 2025;8:e67877

School-Based Virtual Reality Programming for Obtaining Moderate-Intensity Exercise Among Children With Disabilities: Pre-Post Feasibility Study

School-Based Virtual Reality Programming for Obtaining Moderate-Intensity Exercise Among Children With Disabilities: Pre-Post Feasibility Study

These findings are also supported by more overarching reviews of disability exercise studies outside of the school setting [2]. Children with mobility disabilities who cannot walk, run, or cycle for prolonged periods have very few evidenced aerobic exercise modalities for improving their cardiometabolic health and cardiorespiratory fitness [2,14,15]. Active video gaming is one of the few evidenced aerobic exercise modalities that can improve health among children with disabilities [14,15].

Byron Lai, Ashley Wright, Bailey Hutchinson, Larsen Bright, Raven Young, Drew Davis, Sultan Ali Malik, James H Rimmer, Pelham High Community Engagement Group

JMIR Form Res 2025;9:e65801

Development of a Longitudinal Model for Disability Prediction in Older Adults in China: Analysis of CHARLS Data (2015-2020)

Development of a Longitudinal Model for Disability Prediction in Older Adults in China: Analysis of CHARLS Data (2015-2020)

Therefore, accurate prediction of disability is crucial for early intervention and effective management. Despite significant research efforts to forecast disability in older adults, existing models often lack sufficient precision and fail to account for the complex, multifactorial nature of disability. These models typically overlook the broader context of risk factors and offer limited utility for public health decision-making [4-6].

Jingjing Chu, Ying Li, Xinyi Wang, Qun Xu, Zherong Xu

JMIR Aging 2025;8:e66723

Accelerometry-Assessed Physical Activity and Circadian Rhythm to Detect Clinical Disability Status in Multiple Sclerosis: Cross-Sectional Study

Accelerometry-Assessed Physical Activity and Circadian Rhythm to Detect Clinical Disability Status in Multiple Sclerosis: Cross-Sectional Study

Multiple sclerosis (MS) is a chronic disease affecting the central nervous system in which those affected typically have intermittent neurologic symptoms and signs early in the course (relapsing-remitting multiple sclerosis [RRMS]) but often, subsequently (or, less commonly, from onset), slowly accumulate disability (progressive multiple sclerosis [PMS]). Currently available tools to measure disability in MS are limited.

Nicole Bou Rjeily, Muraleetharan Sanjayan, Pratim Guha Niyogi, Blake E Dewey, Alexandra Zambriczki Lee, Christy Hulett, Gabriella Dagher, Chen Hu, Rafal D Mazur, Elena M Kenney, Erin Brennan, Anna DuVal, Peter A Calabresi, Vadim Zipunnikov, Kathryn C Fitzgerald, Ellen M Mowry

JMIR Mhealth Uhealth 2025;13:e57599

Accessibility of eHealth Before and During the COVID-19 Pandemic Among People With and People Without Impairment: Repeated Cross-Sectional Survey

Accessibility of eHealth Before and During the COVID-19 Pandemic Among People With and People Without Impairment: Repeated Cross-Sectional Survey

Before the pandemic, we identified a disability digital divide in e Health, that is, people with impairment reported less use and more difficulty in the use of e Health, particularly with some types of impairment (language impairments and intellectual impairments) [2]. Sustainable development [3], legislation, and human rights principles [4] demand accessible e Health for all.

Linda Pettersson, Stefan Johansson, Ingrid Demmelmaier, Lena von Koch, Jan Gulliksen, Per-Olof Hedvall, Karl Gummesson, Catharina Gustavsson

JMIR Public Health Surveill 2025;11:e64707

A Brief Cognitive Behavioral Therapy–Based Digital Intervention for Reducing Hazardous Alcohol Use in South Korea: Development and Prospective Pilot Study

A Brief Cognitive Behavioral Therapy–Based Digital Intervention for Reducing Hazardous Alcohol Use in South Korea: Development and Prospective Pilot Study

It is a leading cause of death and disability globally, contributing to a wide range of acute and chronic medical conditions. Acute medical consequences of high alcohol intake include injuries, car accidents, and violence [3]. Chronic diseases associated with alcohol consumption include liver cirrhosis, cardiovascular diseases, and various cancers [4-8].

Manjae Kwon, Daa Un Moon, Minjae Kang, Young-Chul Jung

JMIR Form Res 2025;9:e64459

Indigenous Community Views of Disability in Canada: Protocol for a Scoping Review

Indigenous Community Views of Disability in Canada: Protocol for a Scoping Review

The way disability is defined affects the types of disability services offered, who uses the services, and the way they work. The traditional biomedical model, despite frequent criticism, continues to influence Western approaches to disability [1,2]. This model views disability as an individual issue, characterized by abnormalities of the body or mind that medical science treats and social services cater for.

Andrés Rojas-Cárdenas, Shaun Cleaver, Ivan Sarmiento, Julie Rock, Yan Grenier, Francis Charrier, Rose-Anne Gosselin, Anne Cockcroft, Neil Andersson

JMIR Res Protoc 2025;14:e57590

Evaluation of Financial Support Workshops for Patients Under State Pension Age With Degenerative Cervical Myelopathy: Survey Study

Evaluation of Financial Support Workshops for Patients Under State Pension Age With Degenerative Cervical Myelopathy: Survey Study

People with DCM experience high levels of disability and dependence, and are among those with the lowest quality of life scores for any chronic disease [13]. In fact, almost half of diagnosed individuals may be dependent on the support of others for activities of daily living (41.9% (326/778) in a recent study [14]).

Tanzil Rujeedawa, Zahabiya Karimi, Helen Wood, Irina Sangeorzan, Roy Smith, Iwan Sadler, Esther Martin-Moore, Adrian Gardner, Andreas K Demetriades, Rohitashwa Sinha, Gordan Grahovac, Antony Bateman, Naomi Deakin, Benjamin Davies

JMIR Form Res 2025;9:e59032