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Identifying Deprescribing Opportunities With Large Language Models in Older Adults: Retrospective Cohort Study

Identifying Deprescribing Opportunities With Large Language Models in Older Adults: Retrospective Cohort Study

Improved uncertainty calibration in LLMs could enhance selective prediction methods, optimizing physician-artificial intelligence (AI) workflows in clinical settings. Future applications of a well-calibrated deprescribing CDS tool could flag cases where critical information is missing (eg, antipsychotics at unchanged doses for more than 3 months without a documented medication review).

Vimig Socrates, Donald S Wright, Thomas Huang, Soraya Fereydooni, Christine Dien, Ling Chi, Jesse Albano, Brian Patterson, Naga Sasidhar Kanaparthy, Catherine X Wright, Andrew Loza, David Chartash, Mark Iscoe, Richard Andrew Taylor

JMIR Aging 2025;8:e69504

Creating a Modified Version of the Cambridge Multimorbidity Score to Predict Mortality in People Older Than 16 Years: Model Development and Validation

Creating a Modified Version of the Cambridge Multimorbidity Score to Predict Mortality in People Older Than 16 Years: Model Development and Validation

Model performance evaluation was based on discrimination and calibration. Discrimination was assessed by the pseudo R2, Somers D, and Harrell C [33]. Model calibration was evaluated by plotting a calibration curve and recalibration was carried out by resampling using cross-validation to correct for optimism or overfitting. This was implemented using the “calibrate” function in the rms R package.

Debasish Kar, Kathryn S Taylor, Mark Joy, Sudhir Venkatesan, Wilhelmine Meeraus, Sylvia Taylor, Sneha N Anand, Filipa Ferreira, Gavin Jamie, Xuejuan Fan, Simon de Lusignan

J Med Internet Res 2024;26:e56042

The Accuracy of Tidal Volume Measured With a Smart Shirt During Tasks of Daily Living in Healthy Subjects: Cross-sectional Study

The Accuracy of Tidal Volume Measured With a Smart Shirt During Tasks of Daily Living in Healthy Subjects: Cross-sectional Study

All TV values in a task were used to determine calibration factors a and b with least squares linear regression (see equation 1). This resulted in 15×7 sets of calibration factors. After calibration, an averaging window of 5 TVs was applied to all data to perform further analysis. The seven calibration functions from session 1 were applied to the seven tasks of session 2 to determine accuracy after removal of the Hexoskin.

Denise Mannée, Frans de Jongh, Hanneke van Helvoort

JMIR Form Res 2021;5(10):e30916

Hearing Tests on Mobile Devices: Evaluation of the Reference Sound Level by Means of Biological Calibration

Hearing Tests on Mobile Devices: Evaluation of the Reference Sound Level by Means of Biological Calibration

Calibration could also be conducted to verify the reference sound level used during the examination. Therefore, the calibration measurements, which are subject of interest in this paper, were not the outcome of intended actions but resulted from the wish to conduct the hearing test or to verify the test results. All the users who conducted calibration using the bundled headphones were assigned to the uncontrolled group. Detailed instructions on calibration were presented directly before the measurement.

Marcin Masalski, Lech Kipiński, Tomasz Grysiński, Tomasz Kręcicki

J Med Internet Res 2016;18(5):e130