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Relationship Between Within-Session Digital Motor Skill Acquisition and Alzheimer Disease Risk Factors Among the MindCrowd Cohort: Cross-Sectional Descriptive Study

Relationship Between Within-Session Digital Motor Skill Acquisition and Alzheimer Disease Risk Factors Among the MindCrowd Cohort: Cross-Sectional Descriptive Study

Genetic, demographic, cognitive, motor, and Super G performance data between APOE ε4 carries and noncarriers. a N/A: not applicable. b Statistical significance (P c PAL: paired associates learning. dsv RT: simple visual reaction time. e Based on 24-hour clock. Within the APOE ε4 carrier status logistic regression (model 1) there was a significant association between APOE ε4 carrier status with Super G RT (OR 0.12, 95% CI 0.02-0.44; P=.006) (Figure 2 A).

Andrew Hooyman, Matt J Huentelman, Matt De Both, Lee Ryan, Kevin Duff, Sydney Y Schaefer

JMIR Aging 2025;8:e67298