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Skip search results from other journals and go to results- 318 Journal of Medical Internet Research
- 249 JMIR Mental Health
- 215 JMIR Formative Research
- 163 JMIR Research Protocols
- 63 JMIR mHealth and uHealth
- 33 JMIR Public Health and Surveillance
- 19 JMIR Human Factors
- 17 JMIR Pediatrics and Parenting
- 15 JMIR Serious Games
- 13 Interactive Journal of Medical Research
- 11 JMIR Aging
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- 3 JMIR AI
- 3 JMIR Neurotechnology
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- 2 JMIR Medical Education
- 2 JMIR Rehabilitation and Assistive Technologies
- 2 Journal of Participatory Medicine
- 1 Asian/Pacific Island Nursing Journal
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- 1 Online Journal of Public Health Informatics
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In 2019, an estimated 301 million working-age adults experienced anxiety, while approximately 280 million had depression [1]. Furthermore, many workers report subclinical symptoms such as psychological distress [2-4]. These mental health concerns lead to increased absenteeism, deteriorating quality of life, and overall well-being [5]. The global economic burden of mental health conditions is estimated at approximately US $1 trillion annually, primarily due to productivity losses [1,6,7].
JMIR Mhealth Uhealth 2025;13:e70473
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Depression is prevalent and a leading cause of disability, mortality, loss of productivity, and health care expenditure [1]. Psychological interventions not only are effective for the treatment of depression [2] but are also considered a first-line treatment for major depression [3]. Psychological interventions are also the preferred treatment method for most people with depression [4].
J Med Internet Res 2025;27:e54727
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Approximately 280 million people worldwide are experiencing depression [1], and nearly half of those people also experience comorbid anxiety [2]. Symptoms of either disorder can cause substantial distress and impair functioning across all domains of life. Worse yet, the prevalence and severity of these disorders are growing [3].
JMIR Res Protoc 2025;14:e65970
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Numerous studies have shown that the prevalence rates of clinically relevant mental health problems, such as symptoms of depression, anxiety disorders, and psychosomatic illnesses, are increased in the unemployed population compared with the employed population [6,7]. While the point prevalence of depression in the general population ranges between 6.38% [8] and 12.9% [9], an aggregate increased prevalence of 24% persists for individuals who are unemployed [7].
JMIR Public Health Surveill 2025;11:e65698
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The COVID-19 pandemic exacerbated almost every mental health disorder, including anxiety, depression [1], and eating disorders (EDs) [2]. EDs are associated with high rates of morbidity and mortality [3], and poor quality of life [4]. Schlegl et al [2] found that while 70% of patients with EDs reported an increase in symptoms after the onset of COVID-19, access to in-person therapy decreased by 37% at the same time. Only 26% of patients surveyed used videoconferencing for therapy.
J Med Internet Res 2025;27:e66465
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The distress experiences were measured using the Depression Anxiety Stress Scale (DASS), which consists of 21 items divided into 3 subscales, with 7 items each, measuring depression, anxiety, and stress [38]. Items were rated on a 4-point Likert-type scale, ranging from 0 (did not apply) to 3 (applied most of the time). Total scores for each dimension were obtained by summing the item scores of the subscales, with possible totals ranging from 0 to 21 for each of the 3 factors.
J Med Internet Res 2025;27:e70680
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Depression is associated with a negative bias in the interpretation of facial emotional expressions [1,2]. This negative bias has been proposed to play an important role in the onset and maintenance of depression, as successful pharmacological interventions have been found to be associated with the reduction of negative biases [3]. It was previously thought that treating depression would lead to improvements in emotion recognition bias.
JMIR Serious Games 2025;13:e65103
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Because depression [32] and PTSD [33] frequently co-occur with anxiety, we also investigated the efficacy of transauricular ultrasound VNS for alleviating the symptoms of depression and PTSD in individuals with anxiety.
This was a pre-post-intervention study in which all participants received the intervention daily, at home, for a period of 4 weeks. The clinical trial is registered at Clinical Trials.gov [NCT06574971]. Informed consent was obtained from each of the 28 participants prior to screening.
JMIR Neurotech 2025;4:e69770
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Perinatal depression and anxiety (PNDA) negatively impact the health and well-being of mothers and babies, and disrupt maternal /infant bonding [1]. Recent studies highlighted the significant association between PNDA and adverse outcomes, including suicidal behaviors and self-harm thoughts during and after pregnancy. Roddy Mitchell et al [2] emphasized the increased risk of preterm birth, stillbirth, and suicide associated with PNDA.
J Med Internet Res 2025;27:e68030
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Recent studies have also underscored the importance of mobile health interventions specifically designed for pregnant women, highlighting their effectiveness in reducing anxiety and depression symptoms during pregnancy [5,28].
JMIR Hum Factors 2025;12:e71708
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