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Developing an Equitable Machine Learning–Based Music Intervention for Older Adults At Risk for Alzheimer Disease: Protocol for Algorithm Development and Validation

Developing an Equitable Machine Learning–Based Music Intervention for Older Adults At Risk for Alzheimer Disease: Protocol for Algorithm Development and Validation

One digital music intervention, Sing Fit, was developed to improve well-being and mood symptoms for both those at risk for and those living with AD (Figure 1). The use of singing to manage symptoms of depression is based on research showing that music interventions and music learning are associated with improvements in cognitive reserve, well-being, and mood symptoms related to depression [16-19].

Chelsea S Brown, Luna Dziewietin, Virginia Partridge, Jennifer Rae Myers

JMIR Res Protoc 2025;14:e73711


Using Music to Promote Hong Kong Young People’s Emotion Regulation and Reduce Their Mood Symptoms and Loneliness: Protocol for a Pilot Randomized Controlled Trial

Using Music to Promote Hong Kong Young People’s Emotion Regulation and Reduce Their Mood Symptoms and Loneliness: Protocol for a Pilot Randomized Controlled Trial

Distinct from the term song, which refers to a short composition combining both words and music, music is considered a hypernym of song. In other words, music is a broader term that encompasses a range of activities—from listening to background music to engaging in composition and improvisation [12]—whereas song specifically refers to music with lyrics that can be sung [13].

Yuan Cao, Yuanxin Shi, Debbie Chi Wing Low, Daniel T L Shek, David H K Shum, Radhika Tanksale, Genevieve Dingle

JMIR Res Protoc 2025;14:e67764


Effectiveness of a Virtual Reality Serious Video Game (The Secret Trail of Moon) for Emotional Regulation in Children With Attention-Deficit/Hyperactivity Disorder: Randomized Clinical Trial

Effectiveness of a Virtual Reality Serious Video Game (The Secret Trail of Moon) for Emotional Regulation in Children With Attention-Deficit/Hyperactivity Disorder: Randomized Clinical Trial

Music can help modulate these emotional states besides facilitating flow and immersion while playing video games [25]. Particularly in ADHD, music can be beneficial in reducing environmental distraction, especially in monotonous tasks [25,26]. Elements of music therapy have been both passively and interactively incorporated into this new version of the game [25,27].

Marina Martin-Moratinos, Marcos Bella-Fernández, María Rodrigo-Yanguas, Carlos González-Tardón, Chao Li, Ping Wang, Ana Royuela, Pilar Lopez-Garcia, Hilario Blasco-Fontecilla

JMIR Serious Games 2025;13:e59124


An Analysis of the Prevalence and Trends in Drug-Related Lyrics on Twitter (X): Quantitative Approach

An Analysis of the Prevalence and Trends in Drug-Related Lyrics on Twitter (X): Quantitative Approach

Various studies and publications relate drug lyrics in music to substance use content on social media. These studies probe the influential role of music in shaping individuals’ identities and behaviors, and the direct impact musicians have on their followers [17]. Studies show that there is an association between music preferences and drug abuse patterns, focusing on heavy metal music as an example.

Waylon Luo, Ruoming Jin, Deric Kenne, NhatHai Phan, Tang Tang

JMIR Form Res 2024;8:e49567


Mental Health Benefits of Listening to Music During COVID-19 Quarantine: Cross-Sectional Study

Mental Health Benefits of Listening to Music During COVID-19 Quarantine: Cross-Sectional Study

Music is ubiquitous in people’s daily lives, and listening to music is a popular leisure activity that benefits individual well-being. During the COVID-19 outbreak, music was widely used by individuals as an emotional resource to sustain them through difficult times.

Xuechang Xian, Xiaoran Zhang, Danhe Zheng, Yanlin Wang

JMIR Form Res 2024;8:e46497


Impact of Dance or Music and Meditation on the Progression of Parkinson Disease With Mild or Moderate Severity: Protocol for a Pilot Randomized Controlled Trial

Impact of Dance or Music and Meditation on the Progression of Parkinson Disease With Mild or Moderate Severity: Protocol for a Pilot Randomized Controlled Trial

It is seen that alternative therapies such as music, dance, and mindfulness might help delay the progression of PD symptomatology while improving the quality of life (Qo L) [11,12]. In addition, therapies such as exercise and aerobic dance can have neuroprotective effects led by neuroplasticity [13]. Exercise is further seen to modulate dopamine neurotransmission [14]. It has been observed that music modulates the brain regions related to movement, behavior, and cognitive processes [15].

Bhagyashree Mehrotra, Neha Rai, Rajani MR, Aparna Budhakar, Ritika Aggarwal, Raj Vinodkumar Agarbattiwala, Mona Thomas, Sampada Patole, Paresh Doshi

JMIR Res Protoc 2024;13:e59018


Current Evidence of the Application of Music in Tai Chi Exercise: Scoping Review

Current Evidence of the Application of Music in Tai Chi Exercise: Scoping Review

Gender: 100% female Intervention: Tai Chi with music Control: Tai Chi without music Not mentioned Tai Chi learning motivation Concentration Satisfaction with instruction Overall performance (correctness, consistency, pace, style, overall) Age: not available Intervention: Tai Chi with music (n=30); Tai Chi only (n=30); music only (n=30). Control: nonactive (n=30). Gender: not available Intervention (three groups): (1) Tai Chi with music; (2) Tai Chi only; (3) music only.

Yan Du, Gao-Xia Wei, Yichao He, Hongting Ning, Penny Roberts, Edward Golob, Zenong Yin

Asian Pac Isl Nurs J 2024;8:e60104


Analyzing the Influence of Video Game and Music Engagement on Technical Skills Acquisition in Dental Students in Preclinical Phase: Protocol for a Prospective, Controlled, Longitudinal Study

Analyzing the Influence of Video Game and Music Engagement on Technical Skills Acquisition in Dental Students in Preclinical Phase: Protocol for a Prospective, Controlled, Longitudinal Study

Assignment of the subject to the “music players” group if the student describes an hourly habit of using a musical instrument based on 0-60 minutes per week for occasional players, 61-300 minutes per week for moderate players, or more than 300 minutes per week for regular players. These values are used to be consistent with those used to define a video game player profile. The methods used in other studies to define a music player were either too subjective or too complicated to implement.

Roselyne Clouet, Alexis Gaudin, Jeanne Tourtelier, Claire Gogendeau, Samuel Serisier, Tony Prud'homme

JMIR Res Protoc 2024;13:e55738


Effects of Background Music on Attentional Networks of Children With and Without Attention Deficit/Hyperactivity Disorder: Case Control Experimental Study

Effects of Background Music on Attentional Networks of Children With and Without Attention Deficit/Hyperactivity Disorder: Case Control Experimental Study

The intervention required participants to perform an attention task in 2 different conditions: with music and without music. The music selection comprised 5 songs chosen through interviews with children aged 10 to 12 years, who shared their favorite and most frequently listened-to songs. These songs were played during the test. It is important to note that the children interviewed about their favorite music were not necessarily participants in the study.

Camila Guimarães Mendes, Jonas Jardim de Paula, Débora Marques Miranda

Interact J Med Res 2024;13:e53869


Effectiveness of a Serious Video Game (MOON) for Attention Deficit Hyperactivity Disorder: Protocol for a Randomized Clinical Trial

Effectiveness of a Serious Video Game (MOON) for Attention Deficit Hyperactivity Disorder: Protocol for a Randomized Clinical Trial

Some studies show promising results with cognitive training [21], metacognitive interventions [22], music [23], and video games [24]. However, the overall results show small effect sizes and difficulties in maintaining long-term benefits and transferability to daily life (generalizability and transferability) [25]. More evidence is needed with greater control of risk biases. Video games provide immersive and engaging entertainment experiences.

Marina Martin-Moratinos, Marcos Bella-Fernández, Maria Rodrigo-Yanguas, Carlos González-Tardón, Aaron Sújar, Chao Li, Ping Wang, Ana Royuela, Pilar Lopez-Garcia, Hilario Blasco-Fontecilla

JMIR Res Protoc 2024;13:e53191