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Quality of Life Among Family Caregivers of Individuals With Rare Diseases: Web-Based Population Study on the Validity and Reliability of the Polish World Health Organization Quality of Life-BREF Questionnaire

Quality of Life Among Family Caregivers of Individuals With Rare Diseases: Web-Based Population Study on the Validity and Reliability of the Polish World Health Organization Quality of Life-BREF Questionnaire

However, this validation process overlooked caregivers, an essential yet often neglected population in HRQo L research. Caregivers play a vital role in the health care system, providing continuous support to individuals with chronic illnesses and disabilities. Despite their crucial contributions, caregivers often experience significant physical, emotional, and financial burdens, which in turn affect their own Qo L [10-13]. Caregivers of persons with RDs face particularly severe challenges.

Piotr Jabkowski, Jan Domaradzki, Dariusz Walkowiak

JMIR Public Health Surveill 2025;11:e72590

Facial Emotion Recognition of 16 Distinct Emotions From Smartphone Videos: Comparative Study of Machine Learning and Human Performance

Facial Emotion Recognition of 16 Distinct Emotions From Smartphone Videos: Comparative Study of Machine Learning and Human Performance

The test set used for the validation of the newly developed models was taken from the STREs Wo Z dataset and comprised 13 individuals displaying 1 of the 16 emotions. All individuals were women, with a mean age of 20.92 (SD 2.06; range 18-24) years, White, and—except for 1—reported elevated subjective stress levels. The test set included 3018 videos. For the validation with human observers, they were not only shown the emotional phase but the entire videos.

Marie Keinert, Simon Pistrosch, Adria Mallol-Ragolta, Björn W Schuller, Matthias Berking

J Med Internet Res 2025;27:e68942

Proposal for Using AI to Assess Clinical Data Integrity and Generate Metadata: Algorithm Development and Validation

Proposal for Using AI to Assess Clinical Data Integrity and Generate Metadata: Algorithm Development and Validation

Finally, the datasets were divided into training and test sets and validated using 5x10-fold cross-validation. Since it is not feasible to universally preselect suitable algorithms in advance, it was necessary to test and evaluate various learning algorithms tailored to specific scenarios [25]. The LR algorithm was selected as the baseline for classification tasks because it predicts the probability of a target variable and is widely used in both binary and multiclass classifications.

Caroline Bönisch, Christian Schmidt, Dorothea Kesztyüs, Hans A Kestler, Tibor Kesztyüs

JMIR Med Inform 2025;13:e60204

Remote Photoplethysmography Technology for Blood Pressure and Hemoglobin Level Assessment in the Preoperative Assessment Setting: Algorithm Development Study

Remote Photoplethysmography Technology for Blood Pressure and Hemoglobin Level Assessment in the Preoperative Assessment Setting: Algorithm Development Study

The shuffled dataset was then divided into training, validation, and testing sets comprising 2758, 592 and 591 data points respectively. Our approach used a U-Net-based model enhanced with label distribution smoothing (LDS) techniques [28]. The model optimization leveraged the Adam optimizer, chosen for its efficient handling of large datasets and adaptability in gradient-based optimization.

Selene Y L Tan, Jia Xin Chai, Minwoo Choi, Umair Javaid, Brenda Pei Yi Tan, Belinda Si Ying Chow, Hairil Rizal Abdullah

JMIR Form Res 2025;9:e60455

Toward Interoperable Digital Medication Records on Fast Healthcare Interoperability Resources: Development and Technical Validation of a Minimal Core Dataset

Toward Interoperable Digital Medication Records on Fast Healthcare Interoperability Resources: Development and Technical Validation of a Minimal Core Dataset

We rely on MII assets for terminology services, validation, and profile conformance. To implement this solution, we propose creating a FHIR server, built upon an open-source FHIR implementation such as HAPI FHIR. The server would facilitate the interoperable exchange of medication data between existing hospital systems.

Eduardo Salgado-Baez, Raphael Heidepriem, Renate Delucchi Danhier, Eugenia Rinaldi, Vishnu Ravi, Akira-Sebastian Poncette, Iris Dahlhaus, Daniel Fürstenau, Felix Balzer, Sylvia Thun, Julian Sass

JMIR Med Inform 2025;13:e64099

Development and Validation of the Media Health Literacy Scale: Assessment Tool Development Study

Development and Validation of the Media Health Literacy Scale: Assessment Tool Development Study

A total of 30 participants representing general consumers who were not health care professionals completed the revised MHLS draft generated from the content validation and provided comments for further revision. A survey was conducted for construct validation using the MHLS semifinalized draft prepared based on the content validation and the pilot testing. The process included descriptive analysis, item analysis, factor analysis, and reliability tests.

Sangyoon Shin, Seungyeon Kim, Youngshin Song, Hyesun Jeong, Yun Mi Yu, Euni Lee

J Med Internet Res 2025;27:e62884

Education and Symptom Reporting in an mHealth App for Patients With Cancer: Mixed Methods Development and Validation Study

Education and Symptom Reporting in an mHealth App for Patients With Cancer: Mixed Methods Development and Validation Study

Additionally, it shows the results of validation and quality assessment of the mobile application “CONTIGO” by using the MARS, which allows m Health developers to maximize the application’s benefits to significantly impact the patient [22,30-36]. This study employed a mixed methods approach. This methodology is presented in two sections: (1) design a mobile application, and (2) validation and quality assessment.

Carolina Muñoz Olivar, Miguel Pineiro, Juan Sebastián Gómez Quintero, Carlos Javier Avendaño-Vásquez, Pablo Ormeño-Arriagada, Silvia Palma Rivadeneira, Carla Taramasco Toro

JMIR Hum Factors 2025;12:e60169

Validation of an Adaptive Assessment of Executive Functions (Adaptive Cognitive Evaluation-Explorer): Longitudinal and Cross-Sectional Analyses of Cognitive Task Performance

Validation of an Adaptive Assessment of Executive Functions (Adaptive Cognitive Evaluation-Explorer): Longitudinal and Cross-Sectional Analyses of Cognitive Task Performance

Study recruitment and data collection for the ACE-X validation study took place simultaneously between May 2021 and January 2023. Adult participants were recruited via advertising on various social media platforms (eg, Craigslist [Craig Newmark] and Facebook [Meta Platforms]), MTurk (Amazon, Inc), and a Qualtrics (Qualtrics International Inc) recruitment panel.

Kristine D O'Laughlin, Britte Haugan Cheng, Joshua J Volponi, John David A Lorentz, Sophia A Obregon, Jessica Wise Younger, Adam Gazzaley, Melina R Uncapher, Joaquin A Anguera

J Med Internet Res 2025;27:e60041

Daily Automated Prediction of Delirium Risk in Hospitalized Patients: Model Development and Validation

Daily Automated Prediction of Delirium Risk in Hospitalized Patients: Model Development and Validation

We used 10-fold cross-validation [25] for hyperparameter tuning to minimize overfitting. Hyperparameters (such as lambda for L1 regularization) were tuned using a grid search. All development was done using the Ubuntu 18.04 distribution of Gnu-Linux. Data processing and analysis were performed using the Python [26] and Julia [27] programming languages. The code used to generate the models and figures is publicly available [28].

Kendrick Matthew Shaw, Yu-Ping Shao, Manohar Ghanta, Valdery Moura Junior, Eyal Y Kimchi, Timothy T Houle, Oluwaseun Akeju, Michael Brandon Westover

JMIR Med Inform 2025;13:e60442

Correction: Patients’ Experienced Usability and Satisfaction With Digital Health Solutions in a Home Setting: Instrument Validation Study

Correction: Patients’ Experienced Usability and Satisfaction With Digital Health Solutions in a Home Setting: Instrument Validation Study

In “Patients' Experienced Usability and Satisfaction With Digital Health Solutions in a Home Setting: Instrument Validation Study” (JMIR Med Inform 2025 Jan 8:13:e63703) the authors noted two errors. The ORCID for author David P Neal was changed from: 000-0002-5531-9962 To the following: 0000-0001-7916-3299 Additionally, the author “Ellen MA Smets” was changed to “Ellen M A Smets.”

Susan J Oudbier, Ellen M A Smets, Pythia T Nieuwkerk, David P Neal, S Azam Nurmohamed, Hans J Meij, Linda W Dusseljee-Peute

JMIR Med Inform 2025;13:e73416