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Peer Review of “Assessment of SARC-F Sensitivity for Probable Sarcopenia Among Community-Dwelling Older Adults: Cross-Sectional Questionnaire Study”

Peer Review of “Assessment of SARC-F Sensitivity for Probable Sarcopenia Among Community-Dwelling Older Adults: Cross-Sectional Questionnaire Study”

To begin with, SARC-F is a screening indicator for sarcopenia, not for probable sarcopenia (decreased grip strength). If you try to find a cutoff for probable sarcopenia, which is a prestage of sarcopenia, the cutoff value will inevitably be smaller than the cutoff value used to determine sarcopenia. With that in mind, how do you explain the significance of this paper?

Anonymous

JMIRx Med 2025;6:e77582

Authors’ Response to Peer Reviews of “Assessment of SARC-F Sensitivity for Probable Sarcopenia Among Community-Dwelling Older Adults: Cross-Sectional Questionnaire Study”

Authors’ Response to Peer Reviews of “Assessment of SARC-F Sensitivity for Probable Sarcopenia Among Community-Dwelling Older Adults: Cross-Sectional Questionnaire Study”

Introduction: Add a discussion on current research gaps (eg, sarcopenia screening) and clearly explain how your study [2] addresses these gaps. Response: Done. 2. Methods: Include additional clinical outcomes such as muscle function, sarcopenia-related symptoms, or quality of life, and compare how thresholds of ≥2 and ≥4 perform in relation to these outcomes.

David Propst, Lauren Biscardi, Tim Dornemann

JMIRx Med 2025;6:e77497

Assessment of SARC-F Sensitivity for Probable Sarcopenia Among Community-Dwelling Older Adults: Cross-Sectional Questionnaire Study

Assessment of SARC-F Sensitivity for Probable Sarcopenia Among Community-Dwelling Older Adults: Cross-Sectional Questionnaire Study

Individuals that are identified as potentially having sarcopenia through screening undergo a muscular strength test. If strength levels meet the criteria for sarcopenia, muscle quality testing is conducted to confirm the diagnosis [3,6]. Next, the severity of sarcopenia is determined using a physical performance test [3,6].

David Propst, Lauren Biscardi, Tim Dornemann

JMIRx Med 2025;6:e54475

Peer Review of “Assessment of SARC-F Sensitivity for Probable Sarcopenia Among Community-Dwelling Older Adults: Cross-Sectional Questionnaire Study”

Peer Review of “Assessment of SARC-F Sensitivity for Probable Sarcopenia Among Community-Dwelling Older Adults: Cross-Sectional Questionnaire Study”

The authors [1] present an intriguing and clinically valuable finding through their receiver operating characteristic (ROC) curve analysis, suggesting that a SARC-F (strength, assistance with walking, rising from a chair, climbing stairs, and falls) score of ≥2 may serve as a new cutoff value for screening probable sarcopenia. This conclusion has significant potential for improving clinical practice by enhancing early detection.

Anonymous

JMIRx Med 2025;6:e78552

The Cost-Effectiveness of Adding Helicobacter Pylori Screening to the National Gastric Cancer Screening Program in Korea: Protocol for a Cost-Effectiveness Modeling Study

The Cost-Effectiveness of Adding Helicobacter Pylori Screening to the National Gastric Cancer Screening Program in Korea: Protocol for a Cost-Effectiveness Modeling Study

This study aims to provide evidence for the cost-effectiveness of integrating H pylori screening into the NCSP to reduce gastric cancer risk. We are planning to determine the most cost-effective methods of H pylori screening based on age at screening and the frequency of screening. We expect that our study will also identify factors that contribute to improving cost-effectiveness in the National Gastric Cancer Screening Program.

Seowoo Bae, Joon Sung Kim, Moon Won Lee, Gwang Ha Kim, Young-Il Kim, Woon Tae Jung, Gwang Ho Baik, Beom Jin Kim, Joongyub Lee, Mina Suh, Jae Gyu Kim

JMIR Res Protoc 2025;14:e72228

Mental Health Care Guidelines for Telemedicine During the COVID-19 Pandemic: Scoping Review

Mental Health Care Guidelines for Telemedicine During the COVID-19 Pandemic: Scoping Review

We excluded 158 duplicates and 221 articles during the title and abstract screening, resulting in 969 articles for full-text review. By applying the Healthcare Provider Taxonomy of the National Uniform Claim Committee, we excluded 864 articles related to other medical specialties, focusing on 105 articles for TMH guidelines [23].

Julia Ivanova, Triton Ong, Hattie Wilczewski, Mollie Cummins, Hiral Soni, Janelle Barrera, Brandon Welch, Brian Bunnell

JMIR Ment Health 2025;12:e56534

Co-Design of a Health Screening Program Fact Sheet by People Experiencing Homelessness and ChatGPT: Focus Group Study

Co-Design of a Health Screening Program Fact Sheet by People Experiencing Homelessness and ChatGPT: Focus Group Study

To facilitate participation in our oral cancer screening program, the research team decided to aid the initiative with an A5-format, awareness-raising, short health information fact sheet that presents the initiative as acceptable, available, and effective for this vulnerable population [13]. Co-design principles and the technological assistance of the generative artificial intelligence (AI) tool Chat GPT (Open AI) were applied.

Nóra Radó, Orsolya Németh, Sándor Békási

JMIR Form Res 2025;9:e68316

Leveraging Swipe Gesture Interactions From Mobile Games as Indicators of Anxiety and Depression: Exploratory Study

Leveraging Swipe Gesture Interactions From Mobile Games as Indicators of Anxiety and Depression: Exploratory Study

If these data can be harnessed purposefully, mobile games could serve as a widely accessible tool for screening symptoms of mental health disorders such as anxiety and depression. Symptoms of anxiety and depression are a global concern, affecting millions of individuals worldwide [1,2]. However, these conditions often go undiagnosed or untreated due to factors that include resource shortages, lack of trained professionals, societal stigma, and restricted access [3-6].

Vibhav Chitale, Julie D Henry, Ben Matthews, Vanessa Cobham, Nilufar Baghaei

JMIR Ment Health 2025;12:e70577

The Rapid Online Cognitive Assessment for the Detection of Neurocognitive Disorder: Open-Label Study

The Rapid Online Cognitive Assessment for the Detection of Neurocognitive Disorder: Open-Label Study

All screening metrics were expected to be low by chance, with an expected accuracy of 50%, sensitivity of 50%, and negative predictive value of 63%. Following this, we evaluated the actual Ro CA’s screening performance. We began by calculating the confusion matrix of the actual Ro CA by using the optimal threshold of 7/8 (Figure 5 A). We then calculated the screening metrics for Ro CA (Figure 5 B).

Calvin Howard, Amy Johnson, Joseph Peedicail, Marcus C Ng

J Med Internet Res 2025;27:e66735

Chatbot for the Return of Positive Genetic Screening Results for Hereditary Cancer Syndromes: Prompt Engineering Project

Chatbot for the Return of Positive Genetic Screening Results for Hereditary Cancer Syndromes: Prompt Engineering Project

Evaluation criteria. a PGS: population-wide genomic screening. We developed 2 hypothetical scenarios focused on returning results to individuals who participated in PGS. We used scenarios to allow the expert raters to view the chatbot from the perspective of a specific hypothetical patient (Textbox 1). Case 1: Anna A 34-year-old White woman named Anna participated in the In Our DNA SC population-wide genomic screening program in November. She had no personal or family history of cancer.

Emma Coen, Guilherme Del Fiol, Kimberly A Kaphingst, Emerson Borsato, Jackilen Shannon, Hadley Smith, Aaron Masino, Caitlin G Allen

JMIR Cancer 2025;11:e65848