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- 96 Journal of Medical Internet Research
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Reference 1: Behavioral and pharmacotherapy weight loss interventions to prevent obesity-related morbidity Reference 7: The state of obesity: better policies for a healthier America(https://www.tfah.org/wp-content Reference 14: Effectiveness of an app and provider counseling for obesity treatment in primary care Reference 15: Track: a randomized controlled trial of a digital health obesity treatment intervention Reference 16: An internet-based intervention with brief nurse support to manage obesity in primary careobesityObesity and Nutrition as Public Health Problem
JMIR Mhealth Uhealth 2025;13:e58722
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Furthermore, obesity has profound consequences for patients’ quality of life, leading to social and psychological impairments as well as functional limitations [3]. It is considered a global pandemic, currently affecting approximately 1 billion people worldwide, including both adults and children [4].
The treatment of people living with obesity continues to present significant challenges for health care professionals.
J Med Internet Res 2025;27:e72054
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Around 1 in 3 adults in the United Kingdom are affected by obesity [1-4] (defined as abnormal or excessive fat accumulation that presents a risk to health, with a BMI of ≥30 [1]). Many people living with obesity are also burdened by weight-related conditions such as cardiovascular disease, type 2 diabetes, liver disease, and sleep apnea and are at risk of many cancers [1,5]. In addition to poorer physical health, obesity is associated with poorer mental health [6-8] and lower quality of life [9].
JMIR Form Res 2025;9:e71914
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The growing prevalence of childhood obesity is among the most important threats to public health globally [1]. In addition to being at a higher risk of significant childhood comorbidities [2], children living with overweight and obesity are more likely to experience obesity in adulthood [3]. Adults living with obesity are at markedly increased risk of a wide range of noncommunicable diseases, including cardiovascular diseases, diabetes, musculoskeletal disorders, and certain types of cancer [4].
JMIR Form Res 2025;9:e64947
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Obesity is associated with the risk of breast cancer and its recurrence. This relationship involves altered fatty acid metabolism, extracellular matrix remodeling, secretion of adipokines and anabolic and sex hormones, immune dysregulation, and chronic inflammation [1]. A previous systematic meta-analysis showed that women with obesity and breast cancer had poorer survival rates than women without obesity [2].
JMIR Mhealth Uhealth 2025;13:e64846
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With the prevalence of overweight and obesity at approximately 71% among US adults [1,2], there is a critical need for weight loss interventions that are both effective and scalable. Gold standard behavioral obesity treatments are effective in producing weight loss of 5%-8%. These 6-12 month treatments pair frequent counseling with evidence-based behavioral strategies to promote healthy dietary change and physical activity [3,4].
JMIR Res Protoc 2025;14:e75629
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Reference 35: Obesity and excessive weight gain in young adults: new targets for prevention Reference 71: Big data and the transformation of food and beverage marketing: undermining efforts to reduce obesity racially-targeted food marketing and attentional biases on consumption in Black adolescent females with and without obesityobesityObesity and Nutrition as Public Health Problem
JMIR Res Protoc 2025;14:e69096
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A high maternal pre-pregnancy BMI, gestational diabetes mellitus (GDM), and excessive gestational weight gain (GWG; value above the Institute of Medicine recommendations [1]) are prevalent pregnancy conditions that contribute to an in utero environment of overnutrition, leading to significant short- and long-term health ramifications for pregnant people and their children, including increased risks for obesity and diabetes [2-11].
JMIR Res Protoc 2025;14:e72828
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Of this number, >890 million, or approximately 1 in 10 adults, are living with obesity [1]. Obesity is defined as a chronic, systemic illness that is underpinned by excess adiposity that can lead to severe organ dysfunction and life-threatening complications (eg, stroke, cardiovascular disease, type 2 diabetes, depression, and certain types of cancer) [1,2].
JMIR Form Res 2025;9:e81912
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In Mexico, an elevated risk of OSA of 27.3% in adults has been reported, and this risk increases as the BMI is higher. [3]
OSA is estimated to be present in 60% of patients with metabolic syndrome, which can also include, diabetes, obesity, insulin resistance, systemic arterial hypertension, and dyslipidemia [4]. Overweight and obesity contribute to higher amounts of fat in the dilator muscles of neck and tongue, thus increasing OSA.
JMIR Res Protoc 2025;14:e72513
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