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Assessing the Clinical Feasibility of the DiaFocus System for Integrated Personalized Management of Type 2 Diabetes: 6-Month Pilot Cohort Study

Assessing the Clinical Feasibility of the DiaFocus System for Integrated Personalized Management of Type 2 Diabetes: 6-Month Pilot Cohort Study

However, factors beyond medication can impact blood glucose levels, such as stress, physical activity, concomitant diseases, and sleep disturbances [4-6]. Accordingly, diabetes self-management education and support are crucial parts of optimal diabetes management, involving a combination of lifestyle modifications, medication management, and self-care strategies [7].

Nanna Lind, Per Bækgaard, Jakob E Bardram, Claus Cramer-Petersen, Kirsten Nørgaard, Merete B Christensen

JMIR Diabetes 2025;10:e63894


“Digital Clinicians” Performing Obesity Medication Self-Injection Education: Feasibility Randomized Controlled Trial

“Digital Clinicians” Performing Obesity Medication Self-Injection Education: Feasibility Randomized Controlled Trial

Generative AI has been identified to have the potential to offset the clinical and administrative demands associated with the management of patients on these medication types [6] Patient education is a critical component of the clinical care pathway and a prerequisite at many clinics for the prescription of pharmacotherapy. Even in resource-rich countries, the necessary services are not always available.

Sean Coleman, Caitríona Lynch, Hemendra Worlikar, Emily Kelly, Kate Loveys, Andrew J Simpkin, Jane C Walsh, Elizabeth Broadbent, Francis M Finucane, Derek O' Keeffe

JMIR Diabetes 2025;10:e63503


Key Elements and Theoretical Foundations for the Design and Delivery of Text Messages to Boost Medication Adherence in Patients With Diabetes, Hypertension, and Hyperlipidemia: Scoping Review

Key Elements and Theoretical Foundations for the Design and Delivery of Text Messages to Boost Medication Adherence in Patients With Diabetes, Hypertension, and Hyperlipidemia: Scoping Review

Effective management of chronic conditions relies heavily on medication adherence [4], defined as the extent to which individuals follow prescribed medication regimens as suggested by health care professionals [5,6]. High adherence rates are associated with improved clinical outcomes, reduced complications, and lower health care costs [7,8]. However, medication adherence remains suboptimal worldwide, with an estimated global adherence rate of only 50% [9].

Yu-Meng Yang, Tzu Wang, Hsun-Yu Chan, Yen-Ming Huang

J Med Internet Res 2025;27:e71982


Co-Design for Developing and Integrating a Model of Care for Pain Management Centers: Protocol for a Biphase Qualitative Study

Co-Design for Developing and Integrating a Model of Care for Pain Management Centers: Protocol for a Biphase Qualitative Study

This approach incorporates medication, psychosocial support, and physical reconditioning to promote treatment success [5]. Data from an extensive cross-sectional study reported that only 40% of patients with chronic pain consider their condition to be managed adequately [6]. This is possibly due to the lack of literature demonstrating the implementation of evidence-based treatment pathways or models of care (Mo Cs) consistently using this holistic approach [2,6].

Emma Zhao, Lisa Vaccaro, Yi-Ching Lee, Timothy James Brake, Anastasia Serafimovska

JMIR Res Protoc 2025;14:e59126


Size and Composition of Caregiver Networks Who Manage Medications for Persons Living With Dementia: Cross-Sectional Analysis of the 2011-2022 National Health and Aging Trends Study

Size and Composition of Caregiver Networks Who Manage Medications for Persons Living With Dementia: Cross-Sectional Analysis of the 2011-2022 National Health and Aging Trends Study

There are identified disparities in dementia diagnoses and medication management, dementia being more likely among Black and Hispanic persons [5], with family caregivers from historically minoritized racial and ethnic groups helping with medications at increased rates relative to non-Hispanic White caregivers [6,7]. Medication management of person living with dementia can be challenging and stressful for family caregivers [2,3,8].

Reed WR Bratches, Frank Puga, Paul J Barr, Amanda N Leggett, Meredith Masel, James Nicholas Odom, Rita Jablonski

Interact J Med Res 2025;14:e64499


Augmenting Engagement in Decentralized Clinical Trials for Atrial Fibrillation: Development and Implementation of a Programmatic Architecture

Augmenting Engagement in Decentralized Clinical Trials for Atrial Fibrillation: Development and Implementation of a Programmatic Architecture

Summary of assessments at trial time points (baseline 4, 8, and 12 months) in both randomized clinical trials. a AF therapies: pharmacologic or electrical cardioversion, electrophysiologic procedure such as pulmonary vein isolation, or initiation of antiarrhythmic medication. b AF: atrial fibrillation. c PHQ-8: Patient Health Questionnaire. d PROMIS: Patient-reported Outcomes Measurement Information System. e AFEQT: AF Effect on Quality of life.

Toluwa Daniel Omole, Andrew Mrkva, Danielle Ferry, Erin Shepherd, Jessica Caratelli, Noah Davis, Richmond Akatue, Timothy Bickmore, Michael K Paasche-Orlow, Jared W Magnani

JMIR Cardio 2025;9:e66436


The Prevalence and Incidence of Suicidal Thoughts and Behavior in a Smartphone-Delivered Treatment Trial for Body Dysmorphic Disorder: Cohort Study

The Prevalence and Incidence of Suicidal Thoughts and Behavior in a Smartphone-Delivered Treatment Trial for Body Dysmorphic Disorder: Cohort Study

Individuals were excluded if they were currently in therapy, had previously completed 4 or more sessions of CBT for BDD, had undergone psychotropic medication changes less than 2 months before starting the study, reported acute and active suicidal ideation (refer to “Procedures Used for Mitigating Clinical Deterioration and Suicide Risk” section below), or were unable to engage with the smartphone treatment.

Adam C Jaroszewski, Natasha Bailen, Simay I Ipek, Jennifer L Greenberg, Susanne S Hoeppner, Hilary Weingarden, Ivar Snorrason, Sabine Wilhelm

JMIR Ment Health 2025;12:e63605


Adapting a Text Messaging Intervention to Improve Diabetes Medication Adherence in a Spanish-Speaking Population: Qualitative Study

Adapting a Text Messaging Intervention to Improve Diabetes Medication Adherence in a Spanish-Speaking Population: Qualitative Study

While interventions that address patient-reported barriers to diabetes medication adherence can improve glycemic management [20,21], interventions that address barriers to diabetes medication adherence of relevance to Latino adults with T2 D are lacking.

Jacqueline Seiglie, Seth Tobolsky, Ricaurte Crespo Trevino, Lluvia Cordova, Sara Cromer, A Enrique Caballero, Margarita Alegria, J Jaime Miranda, Deborah Wexler, Lindsay Mayberry

JMIR Hum Factors 2025;12:e66668


The Efficacy of Digital Interventions on Adherence to Oral Systemic Anticancer Therapy Among Patients With Cancer: Systematic Review and Meta-Analysis

The Efficacy of Digital Interventions on Adherence to Oral Systemic Anticancer Therapy Among Patients With Cancer: Systematic Review and Meta-Analysis

Adherence measures such as: Medication possession ratio Proportion of days covered Self-reported adherence measures (eg, questionnaires and surveys) Pharmacy refill data Medication event monitoring systems (eg, smart pill bottles and electronic pill caps) Biological markers The study does not contain outcome measures related to adherence. Adherence measures are based solely on subjective reporting (unless validated self-reported measures were used).

Wan-Chuen Liao, Fiona Angus, Jane Conley, Li-Chia Chen

JMIR Cancer 2025;11:e64208