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Effect of Physical Exercise on Telomere Length: Umbrella Review and Meta-Analysis

Effect of Physical Exercise on Telomere Length: Umbrella Review and Meta-Analysis

This type of exercise can induce more robust adaptive responses at the cellular level, including increased expression of genes related to longevity and telomere protection [3]. The aim of this umbrella review was to synthesize existing evidence on the effect of different modalities and durations of physical exercise on TL to inform the implementation of evidence-based physical exercise programs or recommendations to add healthier years into longer lives.

Juan Luis Sánchez-González, Juan Luis Sánchez-Rodríguez, Rogelio González-Sarmiento, Víctor Navarro-López, Raúl Juárez-Vela, Jesús Pérez, Javier Martín-Vallejo

JMIR Aging 2025;8:e64539

Deciphering the Role of Insulin-Like Growth Factor 1 in Endometrial Cancer in Patients With Polycystic Ovary Syndrome: Protocol for a Methodological Approach Using Cell Culture Experiments

Deciphering the Role of Insulin-Like Growth Factor 1 in Endometrial Cancer in Patients With Polycystic Ovary Syndrome: Protocol for a Methodological Approach Using Cell Culture Experiments

Genomic and proteomic approaches [11] have also identified potential new genes and proteins that might explain the link between PCOS and EC and could upregulate genes associated with the insulin signaling pathway in PCOS. Over the past few years, research studies have investigated the potential role of insulin resistance and IGF-1 in the association between PCOS and EC [12,13].

William Atiomo, Fatma Alqutami, Sara Albasha, Mahmood Hachim

JMIR Res Protoc 2023;12:e48127