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Mobile Telehealth Intervention to Support Care Partners of Patients With Alzheimer Disease and Related Dementias (I-CARE 2): Protocol for a Randomized Effectiveness Clinical Trial

Mobile Telehealth Intervention to Support Care Partners of Patients With Alzheimer Disease and Related Dementias (I-CARE 2): Protocol for a Randomized Effectiveness Clinical Trial

The National Plan to address Alzheimer disease and related dementias (ADRD) identifies behavioral and psychological symptoms of dementia (BPSD) as a critical focus of intervention research [1]. BPSD include both behavioral (eg, agitation, aggression, and wandering) and psychological (eg, delusions and hallucinations) symptoms [1].

Jordan R Hill, Bailey Gardner, Miriam J Rodriguez, Lilian Golzarri-Arroyo, Roger S Zoh, Zayn Boustani, Jacqueline Burnell, Evan J Jordan, Malaz A Boustani, Richard J Holden

JMIR Res Protoc 2025;14:e73387


A Mobile App (CareFit) Supporting Physical Activity for Informal Carers of People With Dementia: Mixed Methods Feasibility and Adaptation Study

A Mobile App (CareFit) Supporting Physical Activity for Informal Carers of People With Dementia: Mixed Methods Feasibility and Adaptation Study

Across a growing array of technology [7,8], the development of digital supports for carers of people with dementia continues to be of significant societal interest [9-11]. UK data suggest that 1 in 2 people will be affected by dementia in their lifetime—either by the condition or by caring for someone with dementia (944,000 people currently live with dementia in the United Kingdom) [12].

Kieren J Egan, William Hodgson, Bradley Macdonald, Ramsay Meiklem, Ryan Innes, Alison Kirk, Barbara Fawcett, Mark D Dunlop, Roma Maguire, Greg Flynn, Joshua Stott, Gill Windle

J Med Internet Res 2025;27:e56739


Environmental Triggers of Specific Subtypes of Agitation in People With Dementia: Observational Study

Environmental Triggers of Specific Subtypes of Agitation in People With Dementia: Observational Study

Alongside the cognitive symptoms of dementia, behavioral and psychological symptoms (BPSDs) significantly impact the quality of life of patients and their caregivers [1-4]. Agitation, one of the most critical BPSDs, has been associated with increased caregiver burden [5], earlier institutionalization [6], and more rapid disease progression [7].

Hannah Davidoff, Alex Van Kraaij, Erika Lutin, Laura Van den Bulcke, Mathieu Vandenbulcke, Nick Van Helleputte, Maarten De Vos, Chris Van Hoof, Maarten Van Den Bossche

JMIR Form Res 2025;9:e60274


Addressing Digital Disparities in Alzheimer Disease by Improving Access to Alzheimer Resources for Spanish-Speaking Latino or Latina Individuals in Los Angeles County: Mixed Methods Study

Addressing Digital Disparities in Alzheimer Disease by Improving Access to Alzheimer Resources for Spanish-Speaking Latino or Latina Individuals in Los Angeles County: Mixed Methods Study

In the AD field, websites of organizations detailing available AD services and resources to local communities serve as valuable platforms offering preventive health information and dementia care management tools [15-17]. However, the sudden shift to digital platforms exposed stark disparities in access to informational health services, highlighting the digital divide [18,19].

Stephanie Ovalle-Eliseo, Aisha Mohammed, Gabriela Islas Huerta, Keith Vossel, Lorena H Monserratt, Mirella Díaz-Santos

J Med Internet Res 2025;27:e67147


Evaluating the Accuracy of Web-Based and In-Clinic Subjective Cognitive Decline Assessments in Detecting Cognitive Impairment: Multicohort Study

Evaluating the Accuracy of Web-Based and In-Clinic Subjective Cognitive Decline Assessments in Detecting Cognitive Impairment: Multicohort Study

Dementia is a syndrome characterized by cognitive and noncognitive symptoms, affecting activities of daily living. Alzheimer disease (AD) is the most common cause of dementia, marked by amyloid beta and tau neuropathology, which leads to memory decline and other cognitive symptoms that precede dementia [1]. The recent development of disease-modifying medications such as aducanumab, lecanemab, and donanemab has brought new therapeutic options into clinical practice [2].

Jae Myeong Kang, Manchumad Manjavong, Adam Diaz, Miriam T Ashford, Anna Aaronson, Joseph Eichenbaum, Scott Mackin, Rachana Tank, Melanie J Miller, Bernard Landavazo, Erika Cavallone, Diana Truran, Monica R Camacho, Juliet Fockler, Derek Flenniken, Sarah Tomaszewski Farias, Michael W Weiner, Rachel Nosheny

J Med Internet Res 2025;27:e69689


Virtual Reality Reminiscence Therapy in Dementia Care: Scoping Review of Research

Virtual Reality Reminiscence Therapy in Dementia Care: Scoping Review of Research

People with dementia often experience behavioral and psychological symptoms of dementia (BPSD), including mood disturbances, aggression, irritability, apathy, and emotional dysregulation, which further reduce their quality of life and place significant burdens on caregivers [2,3]. Worldwide, dementia affects a rapidly growing population.

Maria Matsangidou

JMIR XR Spatial Comput 2025;2:e73539


A Dashboard for Managing an Ecosystem and People With Dementia: Protocol for a Healthy Ageing Ecosystem for People With Dementia (HAAL) International Feasibility Pilot Study

A Dashboard for Managing an Ecosystem and People With Dementia: Protocol for a Healthy Ageing Ecosystem for People With Dementia (HAAL) International Feasibility Pilot Study

Healthy Ageing Ecosystem for People With Dementia (HAAL) dashboard. Overview of installed devices used of a patient. Healthy Ageing Ecosystem for People With Dementia (HAAL) dashboard. Focus on data analysis of a device: measurement of sleep quality by Whiz Pad.

Giulio Amabili, Elvira Maranesi, Federico Barbarossa, Arianna Margaritini, Anna Rita Bonfigli, Fong-Chin Su, Chien-Ju Lin, Hsiao-Feng Chieh, Dianne Vasseur, Henk Herman Nap, Yeh-Liang Hsu, Dorothy Bai, Roberta Bevilacqua

JMIR Res Protoc 2025;14:e59860


Enhancing Enrollment and Adherence in Long-Term Wearable Research on Dementia: Qualitative Systematic Review and Meta-Synthesis

Enhancing Enrollment and Adherence in Long-Term Wearable Research on Dementia: Qualitative Systematic Review and Meta-Synthesis

The growing prevalence of dementia and its substantial economic and social impacts have led to increased attention and funding allocations for research supporting persons living with dementia and their caregivers as well as dementia prevention research [1].

Colleen M Peterson, Renée M St Louis, Carol Flannagan

JMIR Aging 2025;8:e63768


Machine Learning–Based Cognitive Assessment With The Autonomous Cognitive Examination: Randomized Controlled Trial

Machine Learning–Based Cognitive Assessment With The Autonomous Cognitive Examination: Randomized Controlled Trial

Current projections estimate 150 million patients living with dementia worldwide by 2050, with 57 million as of 2019 [1]. The aging population presents a considerable diagnostic challenge. This challenge has resulted in diagnostic timelines requiring 3 years or longer from symptom onset [2-6] with a large portion of patients with dementia remaining undiagnosed [2,3,7,8].

Calvin Howard, Amy Johnson, Sheena Baratono, Katharina Faust, Joseph Peedicail, Marcus Ng

J Med Internet Res 2025;27:e67446


Acceptability of an Intervention to Prevent Older Adult Mistreatment Among Family Caregivers to Persons With Dementia: Multimethod Pilot Study

Acceptability of an Intervention to Prevent Older Adult Mistreatment Among Family Caregivers to Persons With Dementia: Multimethod Pilot Study

Among community-dwelling older adults with dementia, 80% receive informal care at home from family caregivers [2]. Despite providing essential care, caregivers, unfortunately, are among the most likely to engage in older adult mistreatment: An estimated one-third to over one-half of caregivers self-report mistreatment toward the care recipient with dementia [3,4].

Kylie Meyer, Wenxing Wei, Jeanine Yonashiro-Cho, Susanna Mage, Sohee Kim, Elliane Irani, Christopher Burant, Zachary Gassoumis, Erin Gentry Lamb, Jaclene A Zauszniewski, Donna Benton

JMIR Form Res 2025;9:e73778