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Centenarian Mortality Rate During COVID-19: Protocol for a Systematic Review and Meta-Analysis
In view of the foregoing, the aim of this study is to investigate the mortality rates in centenarians worldwide due to COVID-19.
The aim of this study is to conduct a systematic review and meta-analysis of studies published between December 2019 and December 2024 on the rate of COVID-19 mortality in centenarians versus other older adults.
JMIR Res Protoc 2025;14:e74068
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As of 2024, there were approximately 722,000 centenarians worldwide, with Japan, the United States, and China having the highest numbers [1]. This figure is expected to rise to 3.4 million by 2050 and exceed 25 million by 2100 [2,3]. In Europe, notable examples include France, Italy, and Greece, each with >20 centenarians per 100,000 inhabitants registered already in 2011.
JMIR Aging 2025;8:e64352
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