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Caregivers’ Perceptions of Clinical Symptoms, Disease Management, and Quality of Life Impact in Cases of Cyclin-Dependent Kinase-Like 5 Deficiency Disorder: Cross-Sectional Online Survey

Caregivers’ Perceptions of Clinical Symptoms, Disease Management, and Quality of Life Impact in Cases of Cyclin-Dependent Kinase-Like 5 Deficiency Disorder: Cross-Sectional Online Survey

Although recent studies have provided major insights on the clinical features and disease management of CDD, research quantifying and qualifying this burden remains limited, given the scarcity of the disorder and its recent identification [14,25-29]. The aim was to better understand the burden of CDD on both patients and their family caregivers and identify unmet needs by analyzing the perspectives of family caregivers in an international cross-sectional survey.

Sam Amin, Carol-Anne Partridge, Helen Leonard, Jenny Downs, Helen Allvin, Valentine Ficara, Emilie Pain, Minna A Korolainen

JMIR Form Res 2025;9:e72489

Assessing the Impact on Electronic Health Record Burden After Five Years of Physician Engagement in a Canadian Mental Health Organization: Mixed-Methods Study

Assessing the Impact on Electronic Health Record Burden After Five Years of Physician Engagement in a Canadian Mental Health Organization: Mixed-Methods Study

The burden caused by the use of electronic health record (EHR) systems continues to be an important issue for health care organizations, especially given human resource shortages in health care systems globally [1-4]. As physicians report spending 2 hours documenting for every hour of patient care, there has been strong interest from many organizations to understand and address the root causes of physician burnout due to EHR burden [5].

Tania Tajirian, Brian Lo, Gillian Strudwick, Adam Tasca, Emily Kendell, Brittany Poynter, Sanjeev Kumar, Po-Yen (Brian) Chang, Candice Kung, Debbie Schachter, Gwyneth Zai, Michael Kiang, Tamara Hoppe, Sara Ling, Uzma Haider, Kavini Rabel, Noelle Coombe, Damian Jankowicz, Sanjeev Sockalingam

JMIR Hum Factors 2025;12:e65656

The Prevalence and Incidence of Suicidal Thoughts and Behavior in a Smartphone-Delivered Treatment Trial for Body Dysmorphic Disorder: Cohort Study

The Prevalence and Incidence of Suicidal Thoughts and Behavior in a Smartphone-Delivered Treatment Trial for Body Dysmorphic Disorder: Cohort Study

Demographic and other data were not collected for people deemed ineligible during screening to reduce burden. During the treatment phase—that is, the first 3 months for participants randomized to immediately receive the app and the first 6 months for those randomized to the waitlist—12 risk alerts were triggered by 11 different participants. All risk alerts were generated from responses to weekly in-app surveys.

Adam C Jaroszewski, Natasha Bailen, Simay I Ipek, Jennifer L Greenberg, Susanne S Hoeppner, Hilary Weingarden, Ivar Snorrason, Sabine Wilhelm

JMIR Ment Health 2025;12:e63605

A Digital Program for Daily Life Management With Endometriosis: Pilot Cohort Study on Symptoms and Quality of Life Among Participants

A Digital Program for Daily Life Management With Endometriosis: Pilot Cohort Study on Symptoms and Quality of Life Among Participants

Over 3 months, the global symptom burden, general level of pain, anxiety, depression, dysmenorrhea, dysuria, chronic fatigue, neuropathic pain, and endo belly improved significantly for the program participants.

Zélia Breton, Emilie Stern, Mathilde Pinault, Delphine Lhuillery, Erick Petit, Pierre Panel, Maïa Alexaline

JMIR Form Res 2025;9:e58262

Traversing Shifting Sands—the Challenges of Caring for Someone With Alzheimer's Disease and the Impact on Care Partners: Social Media Content Analysis

Traversing Shifting Sands—the Challenges of Caring for Someone With Alzheimer's Disease and the Impact on Care Partners: Social Media Content Analysis

Care partners experience an increased burden and more distress as AD severity increases [11-14] and may experience a greater burden than care partners for individuals with other chronic diseases [15]. There is also evidence that care partners experience greater activity impairment, absenteeism (ie, absence from work), impairment related to presenteeism (ie, reduced productivity while at work), and overall work impairment than individuals who are not care partners [16].

Kristian Steen Frederiksen, Julie Hahn-Pedersen, Rebecca Crawford, Ross Morrison, Rose Jeppesen, Lynda Doward, Wendy Weidner

J Med Internet Res 2025;27:e55468

Addressing the “Black Hole” of Low Back Pain Care With Clinical Decision Support: User-Centered Design and Initial Usability Study

Addressing the “Black Hole” of Low Back Pain Care With Clinical Decision Support: User-Centered Design and Initial Usability Study

Low back pain (LBP) is highly prevalent globally, causing personal and societal burden, chronic disability, and substantial health care expenditures, ranging from US $62 to US $124 billion annually in the United States [1-6]. Most LBP is caused by 1 or more benign conditions that are not associated with dangerous pathology [7].

Robert S Rudin, Patricia M Herman, Robert Vining

JMIR Form Res 2025;9:e66666

AI Interventions to Alleviate Healthcare Shortages and Enhance Work Conditions in Critical Care: Qualitative Analysis

AI Interventions to Alleviate Healthcare Shortages and Enhance Work Conditions in Critical Care: Qualitative Analysis

The integration of AI into critical care work presents multifaceted opportunities to enhance job satisfaction and well-being and ease the burden on staff. Specifically, our analysis demonstrates that AI can augment decision-making autonomy, encourage skill diversity and competence development, and increase flexibility—each a critical determinant of job satisfaction, well-being, and professional retention.

Nadine Bienefeld, Emanuela Keller, Gudela Grote

J Med Internet Res 2025;27:e50852

Improving Affordability in Dermatology: Cost Savings in Mark Cuban Cost Plus Drug Company Versus GoodRx

Improving Affordability in Dermatology: Cost Savings in Mark Cuban Cost Plus Drug Company Versus GoodRx

Thus, Cost Plus is a viable tool to reduce prescription medication burden within dermatology and especially among uninsured individuals or those with high-deductible health plans [5]. Cost Plus may offer patients and clinicians more convenience in addition to greater cost savings. For example, the lowest prices in urban regions were derived from dozens of different pharmacies with variable prices. However, in rural areas, patients may have less pharmacy options, leading to higher costs.

Christopher G Youn, Joo Yeon Kim, Vivian B Yang, Gordon H Bae

JMIR Dermatol 2024;7:e64300

Telebehavioral Health for Caregivers of Children With Behavioral Health Needs to Address Caregiver Strain: Cohort Study

Telebehavioral Health for Caregivers of Children With Behavioral Health Needs to Address Caregiver Strain: Cohort Study

Reference 4: Challenges and burden of the coronavirus 2019 (COVID-19) pandemic for child and adolescent Reference 6: Age and family burden among parents of offspring with severe mental illnessburden

Theoren Loo, Myra Altman, David Grodberg, Jennifer La Guardia, Dena Bravata

JMIR Pediatr Parent 2024;7:e59475