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- 207 Journal of Medical Internet Research
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This phase of the project focused on exploring user-centered requirements for developing a text-based and digital human chatbot to alleviate symptoms of mild to moderate anxiety. The primary objective was to map the key topics, preferences, and concerns held by anonymous voluntary participants from the general public regarding a chatbot for mild to moderate anxiety. Ten experts were invited to participate in the construction of the foundation of the survey.
JMIR Form Res 2025;9:e66163
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Users completed the Depression Anxiety Stress Scale-21 (short version; DASS-21) [21] twice via an in-app, self-report questionnaire. The DASS-21 is a well-validated [22-24] measure comprising 3 scales, each with 7 items. Item responses were summed to create continuous scores of depression, anxiety, and stress symptom severity; higher scores indicated greater severity.
JMIR Form Res 2025;9:e71346
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The emotional burden and stressors inherent to the perioperative process commonly result in preoperative anxiety. Up to 75% of children and 50%‐75% of guardians experience preoperative anxiety [1,2]. Indeed, a mutual influence between the patient-guardian dyad can exacerbate or ameliorate the anxiety [3].
JMIR Perioper Med 2025;8:e73392
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Anxiety and depressive disorders represent 2 of the most prevalent and debilitating mental health conditions globally, affecting hundreds of millions of individuals worldwide and imposing substantial personal, social, and economic burdens [1]. In the United States, approximately 31% of adults report experiencing an anxiety disorder at some point in their lives, with 20% reporting anxiety symptoms within the past year [2].
JMIR Mhealth Uhealth 2025;13:e79759
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Disorder-7.
s GAD-7 assesses anxiety symptoms.
J Med Internet Res 2025;27:e71155
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Those aged ≥18 years who responded to the pretest and exhibited mild to moderate symptoms of depression, anxiety, or perceived stress were eligible for inclusion.
JMIR Form Res 2025;9:e71465
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Anxiety is one of the most common psychological symptoms and one of the most common mental illnesses worldwide, and it often starts by the age of 13 years [2]. Anxiety and depression are also the most common mental disorders experienced by children in the United Kingdom [3]. Despite the existence of effective anxiety treatments in England, many children and young people do not receive appropriate, evidence-based, or timely support.
J Med Internet Res 2025;27:e60611
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A cross-sectional study showed that those with medium health anxiety resemble those with high health anxiety rather than those with low anxiety in terms of their internet use and COVID-related anxiety [13]. This marks the importance of a more nuanced focus on adolescents with different base levels of health anxiety.
To fill this gap, we aim to focus on these 2 contradictory, yet likely mutual, perspectives.
J Med Internet Res 2025;27:e66129
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Given their unique experiences, interventions addressing depression and anxiety, specifically for patients with MBC, are urgently needed.
There are few evidence-based interventions targeting depression and anxiety for patients with MBC. A 2023 systematic review identified 13 studies testing supportive care interventions designed to improve quality of life and symptom experience among patients with MBC [15].
JMIR Form Res 2025;9:e77636
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The United States is facing a burgeoning mental health crisis, in which depression and anxiety are at the forefront. Depression and anxiety are pervasive mental health conditions that affect 8.3% and 19.1% of adults each year, respectively [1,2]. They are often chronic and debilitating, with adverse downstream effects on education, employment, and quality of life [1,2]. The clinical presentation of depression and anxiety varies from person to person and between groups [3,4].
JMIR Form Res 2025;9:e73279
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