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Performance of Natural Language Processing versus International Classification of Diseases Codes in Building Registries for Patients With Fall Injury: Retrospective Analysis

Performance of Natural Language Processing versus International Classification of Diseases Codes in Building Registries for Patients With Fall Injury: Retrospective Analysis

This study aimed to assess the performance of NLP algorithms compared to conventional methods for detecting fall incidence and the mechanism of falls obtained from clinical notes of patients with hip fractures. We hypothesize that NLP algorithms outperform fall ICD codes in detecting falls and their mechanisms in patients with hip fractures. A retrospective case-control study was conducted, including the data from 4 tertiary hospitals in Greater Boston, Massachusetts.

Atta Taseh, Souri Sasanfar, Michelle Chan, Evan Sirls, Ara Nazarian, Kayhan Batmanghelich, Jonathan F Bean, Soheil Ashkani-Esfahani

JMIR Med Inform 2025;13:e66973

Validation of The Umbrella Collaboration for Tertiary Evidence Synthesis in Geriatrics: Mixed Methods Study

Validation of The Umbrella Collaboration for Tertiary Evidence Synthesis in Geriatrics: Mixed Methods Study

A more detailed technical description of the algorithms and processes is available in Multimedia Appendix 1. As AI evolves, fully automated synthesis workflows may become feasible, but rigorous validation is essential to ensure trust, transparency, and scientific integrity. The implementation of new methodologies in the scientific field requires a comparative validation process with established methods to confirm their reliability and effectiveness.

Beltran Carrillo, Marta Rubinos-Cuadrado, Jazmin Parellada, Alejandra Palacios, Beltran Carrillo-Rubinos, Fernando Canillas, Juan José Baztán Cortés, Javier Gómez-Pavón

JMIR Form Res 2025;9:e75215

Alert Reduction and Telemonitoring Process Optimization for Improving Efficiency in Remote Patient Monitoring Programs: Framework Development Study

Alert Reduction and Telemonitoring Process Optimization for Improving Efficiency in Remote Patient Monitoring Programs: Framework Development Study

It is however, for many diseases still unclear whether telemonitoring does lead to more efficient care delivery, as it requires a significant time investment (eg, alert processing, development and implementation of telemonitoring algorithms), generates new data, and needs continuous optimization of clinical workflows [6,7]. Modern telemonitoring platforms are often embedded in existing care paths and include clinical algorithms that triage and process the generated alerts [3,8].

Job van Steenkiste, Niki Lupgens, Martijn Kool, Daan Dohmen, Iris Verberk-Jonkers

JMIR Med Inform 2025;13:e66066

Effectiveness of The Umbrella Collaboration Versus Traditional Umbrella Reviews for Evidence Synthesis in Health Care: Protocol for a Validation Study

Effectiveness of The Umbrella Collaboration Versus Traditional Umbrella Reviews for Evidence Synthesis in Health Care: Protocol for a Validation Study

TU is primarily a software-driven system engineered to streamline tertiary evidence synthesis, relying on programmed algorithms to automate the majority of its functions. The core of the system is built on a software infrastructure that processes and synthesizes data from SR/MA abstracts stored in MEDLINE. While AI plays a crucial role, particularly through the use of LLMs and machine learning (ML), it is used selectively within the broader software framework to enhance specific tasks.

Beltran Carrillo, Marta Rubinos-Cuadrado, Jazmin Parellada-Martin, Alejandra Palacios-López, Beltran Carrillo-Rubinos, Fernando Canillas-Del Rey, Juan Jose Baztán-Cortes, Javier Gómez-Pavon

JMIR Res Protoc 2025;14:e67248

Demonstrating Tactical Combat Casualty Care in Simulated Environments to Enable Passive, Autonomous Documentation: Protocol for a Prospective Simulation-Based Study

Demonstrating Tactical Combat Casualty Care in Simulated Environments to Enable Passive, Autonomous Documentation: Protocol for a Prospective Simulation-Based Study

The long-term benefit is the ability to provide a basis for evaluating quality of care and benchmarking key metrics for quality improvement efforts and to leverage machine learning (ML) and artificial intelligence (AI) to enhance future care delivery in the tactical environment, as well as to inform clinical decision support systems and algorithms deployed in these settings [5].

Jeanette R Little, Triana Rivera-Nichols, Holly H Pavliscsak, Omar Badawi, James C Gaudaen, Chevas R Yeoman, Todd S Hall, Ethan T Quist, Ericka L Stoor-Burning

JMIR Res Protoc 2025;14:e67673

Generative AI Models in Time-Varying Biomedical Data: Scoping Review

Generative AI Models in Time-Varying Biomedical Data: Scoping Review

We have organized the paper as follows: (1) overview of the algorithms and techniques introduced in the review; (2) structured data; (3) unstructured data; (4) medical imaging; (5) physiological waveforms; (6) genetics and multi-omics data; and (7) ethical considerations, challenges, and future directions. Health care data sources in different modalities for generative artificial intelligence (AI) application. ECG: electrocardiogram; EEG: electroencephalogram.

Rosemary He, Varuni Sarwal, Xinru Qiu, Yongwen Zhuang, Le Zhang, Yue Liu, Jeffrey Chiang

J Med Internet Res 2025;27:e59792

Trends and Gaps in Digital Precision Hypertension Management: Scoping Review

Trends and Gaps in Digital Precision Hypertension Management: Scoping Review

Digital tools used included mobile phones (2/4, 50%), web platform (1/4, 25%), electronic health record (EHR; 1/4, 25%), machine learning (ML) algorithms (1/4, 25%), BP monitor (1/4, 25%), and genomic databases (1/4, 25%). Summary of the studies on digital phenotyping for HTNa. a HTN: hypertension. b BP: blood pressure. c EHR: electronic health record. d ML: machine learning. e SBP: systolic blood pressure. Of the 4 studies, 2 (50%) used secondary data analysis to apply phenotyping.

Namuun Clifford, Rachel Tunis, Adetimilehin Ariyo, Haoxiang Yu, Hyekyun Rhee, Kavita Radhakrishnan

J Med Internet Res 2025;27:e59841

Identification of Intracranial Germ Cell Tumors Based on Facial Photos: Exploratory Study on the Use of Deep Learning for Software Development

Identification of Intracranial Germ Cell Tumors Based on Facial Photos: Exploratory Study on the Use of Deep Learning for Software Development

Since i GCTs patients exhibit facial feature changes compared with normal children, we hypothesize that facial recognition algorithms can be developed to alert clinicians at the initial consultation, providing personalized diagnostic approaches [9,10]. The application of facial recognition algorithms is extensive, especially those based on machine learning algorithms, which have been profoundly studied in the medical field.

Yanong Li, Yixuan He, Yawei Liu, Bingchen Wang, Bo Li, Xiaoguang Qiu

J Med Internet Res 2025;27:e58760

Combining a Risk Factor Score Designed From Electronic Health Records With a Digital Cytology Image Scoring System to Improve Bladder Cancer Detection: Proof-of-Concept Study

Combining a Risk Factor Score Designed From Electronic Health Records With a Digital Cytology Image Scoring System to Improve Bladder Cancer Detection: Proof-of-Concept Study

Increasing interest in deep learning algorithms has also led to the emergence of new diagnostic strategies based on image processing (see [12,13] for reviews). Although most of them have been developed from cystoscopy images, some aim to propose noninvasive techniques and have exploited images obtained from urine cytology [14-16].

Sandie Cabon, Sarra Brihi, Riadh Fezzani, Morgane Pierre-Jean, Marc Cuggia, Guillaume Bouzillé

J Med Internet Res 2025;27:e56946