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This entails a cross-sectional design with a priori sample size calculations rather than the use of data from longitudinal studies and applying different game levels to investigate whether the game levels induce the appropriate changes in perceived task demands (eg, as has been investigated in the work by Manser and de Bruin [71]) and whether and how performance at higher difficulty levels might differentially relate to cognitive performance assessed using standardized neuropsychological assessments.
JMIR Serious Games 2025;13:e65878
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