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A Mindfulness-Based Lifestyle Intervention for Dementia Risk Reduction: Protocol for the My Healthy Brain Feasibility Randomized Controlled Trial

A Mindfulness-Based Lifestyle Intervention for Dementia Risk Reduction: Protocol for the My Healthy Brain Feasibility Randomized Controlled Trial

Preliminary studies included (1) an in-person clinical pilot (N=24) [64], (2) a telehealth group case series (N=7) [65], and (3) a mixed methods study to adapt the program via qualitative focus groups (N=11) and conduct a feasibility pilot with exit interviews (N=10) [66]. MHB met benchmarks set a priori for feasibility, credibility, satisfaction, and safety (there were no adverse events).

Ryan A Mace, Makenna E Law, Joshua E Cohen, Christine S Ritchie, Olivia I Okereke, Bettina B Hoeppner, Judson A Brewer, Stephen J Bartels, Ana-Maria Vranceanu, My Healthy Brain Team

JMIR Res Protoc 2024;13:e64149

Addressing the Chronic Pain–Early Cognitive Decline Comorbidity Among Older Adults: Protocol for the Active Brains Remote Efficacy Trial

Addressing the Chronic Pain–Early Cognitive Decline Comorbidity Among Older Adults: Protocol for the Active Brains Remote Efficacy Trial

minimum of 6 wk and willing to maintain a stable dose—changing pain or psychotropic medication introduces an additional intervention that may act as a third variable Exclusion criteria and rationale Diagnosed with dementia or another neurodegenerative disease—these individuals would require a different intervention Diagnosed with a medical illness expected to worsen in the next 6 mo (eg, malignancy)—a serious medical illness may act as a third variable Active, untreated serious mental illness or substance use

Ana-Maria Vranceanu, Nathaniel R Choukas, Elizabeth A Rochon, Brooke Duarte, Malvina O Pietrzykowski, Katherine McDermott, Julia E Hooker, Ronald Kulich, Yakeel T Quiroz, Robert A Parker, Eric A Macklin, Christine Ritchie, The Active Brains Project, Ryan A Mace

JMIR Res Protoc 2023;12:e47319

Live Video Mind-Body Program for Patients With Knee Osteoarthritis, Comorbid Depression, and Obesity: Development and Feasibility Pilot Study

Live Video Mind-Body Program for Patients With Knee Osteoarthritis, Comorbid Depression, and Obesity: Development and Feasibility Pilot Study

This is particularly relevant for our patients in Kentucky with this comorbidity, who are underserved and prefer telehealth as a treatment modality. Get Active may be a solution to the problem of comorbid KOA, depression, and obesity, but it requires adaptations.

Ryan A Mace, Jonathan Greenberg, Nicole Lemaster, Brooke Duarte, Terence Penn, Millan Kanaya, James D Doorley, Jessica L Burris, Cale A Jacobs, Ana-Maria Vranceanu

JMIR Form Res 2022;6(4):e34654

A New Tool for Detecting COVID-19 Psychological Burden Among Postacute and Long-term Care Residents (Mood-5 Scale): Observational Study

A New Tool for Detecting COVID-19 Psychological Burden Among Postacute and Long-term Care Residents (Mood-5 Scale): Observational Study

For instance, in a sample of PA/LTC residents referred for evaluation of mood and/or cognitive symptoms, 55% met the criteria for a major depressive episode, and 36.6% met the criteria for generalized anxiety disorder [5]. Although we found no studies investigating the psychological burden associated with COVID-19 in PA/LTC settings, there is evidence suggesting that the pandemic has contributed to an increase in mental health concerns.

William E Mansbach, Ryan A Mace, Melissa A Tanner

JMIR Aging 2021;4(1):e26340

Live Video Adaptations to a Mind-Body Activity Program for Chronic Pain and Cognitive Decline: Protocol for the Virtual Active Brains Study

Live Video Adaptations to a Mind-Body Activity Program for Chronic Pain and Cognitive Decline: Protocol for the Virtual Active Brains Study

The subsequent efficacy randomized controlled trial is outlined by a dashed line. CD: cognitive decline; CP: chronic pain; RCT: randomized controlled trial. These findings informed 2 main decisions in the preparation for a future stage II efficacy trial.

Ryan A Mace, James D Doorley, Paula J Popok, Ana-Maria Vranceanu

JMIR Res Protoc 2021;10(1):e25351