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A Novel Remote Patient and Medication Monitoring Solution to Improve Adherence and Persistence With Inflammatory Bowel Disease Therapy (ASSIST Study): Protocol for a Randomized Controlled Trial

A Novel Remote Patient and Medication Monitoring Solution to Improve Adherence and Persistence With Inflammatory Bowel Disease Therapy (ASSIST Study): Protocol for a Randomized Controlled Trial

Most patients with a chronic condition require long-term therapy. Evidence has demonstrated that suboptimal adherence is associated with poor clinical outcomes, including increased IBD activity and associated complications, worsened quality of life (Qo L) [2], and higher health care use and costs [3]. In addition, nonadherence to biologic therapies may increase the risk for developing antidrug antibodies, leading to loss of response to therapy. Despite this, adherence to IBD therapies remains suboptimal.

Jordan Axelrad, Millie Long, Sara Horst, Anita Afzali, Tamar Sapir, Kristina Fajardo, Kara De Felice, Robert Sandler, Raymond Cross

JMIR Res Protoc 2022;11(12):e40382

Achieving Synergy: Linking an Internet-Based Inflammatory Bowel Disease Cohort to a Community-Based Inception Cohort and Multicentered Cohort in Inflammatory Bowel Disease

Achieving Synergy: Linking an Internet-Based Inflammatory Bowel Disease Cohort to a Community-Based Inception Cohort and Multicentered Cohort in Inflammatory Bowel Disease

CCFA Partners is a validated, Internet-based, long-term cohort study of adult subjects with IBD initiated in July 2011 and administered by the University of North Carolina, Chapel Hill. The development of CCFA Partners has been described in detail previously [23]. In brief, participants with a self-reported diagnosis of UC, CD, or indeterminate colitis were recruited through CCFA email rosters, the CCFA website, social media outlets, and at educational and fundraising events.

Bharati Kochar, Molly Aldridge, Suzanne Follan Cook, Renee Bright, Meaghan Mallette, Heather Moniz, Samir A. Shah, Neal S. LeLeiko, Jason Shapiro, Bruce E. Sands, Wenli Chen, Elizabeth Jaeger, Joseph Galanko, Millie D. Long, Christopher F. Martin, Robert S. Sandler, Michael D. Kappelman

J Med Internet Res 2016;18(6):e124