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Detecting Parkinson Disease Using a Web-Based Speech Task: Observational Study

Detecting Parkinson Disease Using a Web-Based Speech Task: Observational Study

Little et al [12] introduced pitch period entropy (PPE) as a measure of dysphonia to distinguish healthy people from people with PD with 91% accuracy. Later, Tsanas [13] expanded on this by calculating 132 dysphonia measures to classify PD versus control with almost 99% accuracy. In addition, Peker et al [14] used a novel feature selection technique with a complex-valued artificial neural network.

Wasifur Rahman, Sangwu Lee, Md Saiful Islam, Victor Nikhil Antony, Harshil Ratnu, Mohammad Rafayet Ali, Abdullah Al Mamun, Ellen Wagner, Stella Jensen-Roberts, Emma Waddell, Taylor Myers, Meghan Pawlik, Julia Soto, Madeleine Coffey, Aayush Sarkar, Ruth Schneider, Christopher Tarolli, Karlo Lizarraga, Jamie Adams, Max A Little, E Ray Dorsey, Ehsan Hoque

J Med Internet Res 2021;23(10):e26305

Real-Life Gait Performance as a Digital Biomarker for Motor Fluctuations: The Parkinson@Home Validation Study

Real-Life Gait Performance as a Digital Biomarker for Motor Fluctuations: The Parkinson@Home Validation Study

However, these benefits come at a cost: it is challenging to develop algorithms that can cope with the large variation in signals encountered in daily life, of which only a small proportion may be explained by PD-related impairments. Since obtaining accurate labels in daily life environments is difficult and costly, most of the currently available reference data sets have been collected in the lab and involved patients performing a standardized set of tasks and activities.

Luc JW Evers, Yordan P Raykov, Jesse H Krijthe, Ana Lígia Silva de Lima, Reham Badawy, Kasper Claes, Tom M Heskes, Max A Little, Marjan J Meinders, Bastiaan R Bloem

J Med Internet Res 2020;22(10):e19068

Collecting Symptoms and Sensor Data With Consumer Smartwatches (the Knee OsteoArthritis, Linking Activity and Pain Study): Protocol for a Longitudinal, Observational Feasibility Study

Collecting Symptoms and Sensor Data With Consumer Smartwatches (the Knee OsteoArthritis, Linking Activity and Pain Study): Protocol for a Longitudinal, Observational Feasibility Study

Osteoarthritis is an example of such a condition. It is a prevalent, degenerative condition [1,2] where fluctuating pain and loss of mobility are the major symptoms. In knee osteoarthritis, increased physical activity may exacerbate knee pain. Conversely, certain forms of exercise are known to have a beneficial effect on pain symptoms [3,4]. Characterizing the relationship between pain and activity could help in the development of targeted interventions.

Anna L L Beukenhorst, Matthew J Parkes, Louise Cook, Rebecca Barnard, Sabine N van der Veer, Max A Little, Kelly Howells, Caroline Sanders, Jamie C Sergeant, Terence W O'Neill, John McBeth, William G Dixon

JMIR Res Protoc 2019;8(1):e10238