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This system has 3 main components: reactance (Xc), which measures the ability of cell membranes to store electrical charge (capacitance); resistance (R), which represents the resistive properties of cells due to intracellular water (ICW) and extracellular water (ECW) [19]; and impedance (Z), which represents the overall opposition to the electrical current [20]. Impedance provides another opportunity to examine cellular integrity with body cell mass [21].
JMIR Aging 2024;7:e53975
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Next, data processing was performed in R statistical software (R Foundation for Statistical Computing) using the GGIR package (version 2.4-0) [28]. Data processing steps in GGIR include (1) autocalibration of acceleration signals according to local gravity [29], (2) detection of nonwear time, and (3) calculation of the average magnitude of dynamic acceleration corrected for gravity (ie, Euclidean Norm Minus 1 gravitational unit [g; ENMO]) over 5-second epochs, with negative values rounded to 0 [30].
JMIR Aging 2022;5(3):e38172
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The BBS has excellent validity using Pearson correlations (r>0.90) and high test-retest reliability (intraclass correlation coefficient [ICC]=0.83) [44].
Body composition will be assessed using a direct segmental multifrequency BIA using the In Bodys10 device [25]. The BIA is manufactured by Biospace Corporation Limited. The BIA In Body S10 measures impedance at 6 different frequencies (1, 5, 50, 250, 500, and 1000 k Hz) for each body segment (right arm, left arm, trunk, right leg, and left leg).
JMIR Res Protoc 2021;10(4):e27381
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