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A recent meta-analysis reported a 75% increased risk of dementia with deep or mixed CMB [7].
In light of population aging demographics, these figures are concerning, and solutions for early detection of emergent disease and AD risk factors at a preclinical stage to prevent the disease’s development are urgently needed [8]. Neuroimaging methods, such as brain magnetic resonance imaging (MRI) and computerized axial tomography scans, are valuable tools to detect cerebrovascular pathology.
J Med Internet Res 2024;26:e45780
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When potential cognitive impairment decline was present, a clinical review was conducted by a panel with at least one neurologist and one neuropsychologist. MCI diagnosis was determined by the review panel, which required that the participant exhibit evidence of a decline in cognitive performance in 1 or more cognitive domains, have no records indicating functional decline, and do not meet the criteria for dementia [32].
J Med Internet Res 2022;24(12):e42886
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The Clock Drawing Test (CDT) is a widely used assessment tool able to screen for impairment associated with mild cognitive impairment (MCI) [1] and dementia [2-5]. The most common instruction for clock drawing asks participants to draw the face of a clock, put in all of the numbers, and set the hands for 10 past 11. This is followed by asking participants to copy a model of a clock [3,6].
J Med Internet Res 2022;24(4):e34513
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The Clock Drawing Test (CDT) is a widely used neuropsychological test to screen cognitive impairment and dementia because of its ease of administration and clinical assessment capability [1,2]. The test is typically administered by specifying a time, for example, ten past eleven, and asking patients or participants to draw a clock showing that time (the command condition), followed by asking patients or participants to copy a predrawn clock image (the copy condition).
J Med Internet Res 2021;23(6):e27407
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Alzheimer disease (AD) is a chronic neurodegenerative disease characterized by cognitive decline [1]. Neuropsychological (NP) tests—a key measure of phenotypic expression of one’s cognition state—are commonly used by practitioners to assess cognitive dysfunction, especially in the memory, attention, and executive domains [2,3].
J Med Internet Res 2020;22(4):e15376
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