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Development and Pilot Testing of an Addiction Clinic–Based Pre-Exposure Prophylaxis Uptake and Adherence Intervention for Women with Substance Use Disorders: Protocol for a Pilot Randomized Trial

Development and Pilot Testing of an Addiction Clinic–Based Pre-Exposure Prophylaxis Uptake and Adherence Intervention for Women with Substance Use Disorders: Protocol for a Pilot Randomized Trial

After completion of the four motivational sessions, the participant will be scheduled for their initial visit with the nurse practitioner in the CNRA, who will conduct a clinical assessment which will include fourth-generation HIV screening (ie, tests that detect both HIV antibodies and p24 antigens), screening for sexually transmitted infections, a basic metabolic panel to include serum creatinine, and hepatitis B and C screening. The nurse practitioner will review laboratory results.

Angela M Heads, Diane Santa Maria, Mandy J Hill, Robert Suchting, Kimberly N Evans, Zaneta Gaul, Luba Yammine, Constanza de Dios, Joy M Schmitz

JMIR Res Protoc 2025;14:e64961

Evaluating the Accuracy and Reliability of Real-World Digital Mobility Outcomes in Older Adults After Hip Fracture: Cross-Sectional Observational Study

Evaluating the Accuracy and Reliability of Real-World Digital Mobility Outcomes in Older Adults After Hip Fracture: Cross-Sectional Observational Study

The participants after hip fracture were recruited from the Robert Bosch Foundation for Medical Research (Germany) and Kiel University (Germany). The participants were recruited within 13 months of surgical treatment (fixation or arthroplasty) for a low-energy fracture of the proximal femur (International Classification of Diseases, 10th Revision, diagnosis codes S72.0, S72.1, and S72.2), as diagnosed through x-rays of the hip and pelvis. Participants had to be aged ≥65 years to be included.

Martin A Berge, Anisoara Paraschiv-Ionescu, Cameron Kirk, Arne Küderle, Encarna Micó-Amigo, Clemens Becker, Andrea Cereatti, Silvia Del Din, Monika Engdal, Judith Garcia-Aymerich, Karoline B Grønvik, Clint Hansen, Jeffrey M Hausdorff, Jorunn L Helbostad, Carl-Philipp Jansen, Lars Gunnar Johnsen, Jochen Klenk, Sarah Koch, Walter Maetzler, Dimitrios Megaritis, Arne Müller, Lynn Rochester, Lars Schwickert, Kristin Taraldsen, Beatrix Vereijken

JMIR Form Res 2025;9:e67792

Breaking Digital Health Barriers Through a Large Language Model–Based Tool for Automated Observational Medical Outcomes Partnership Mapping: Development and Validation Study

Breaking Digital Health Barriers Through a Large Language Model–Based Tool for Automated Observational Medical Outcomes Partnership Mapping: Development and Validation Study

User interface for clinical data mapping: (A) main dashboard: data import and vocabulary selection interface—the screenshot shows the primary user interface for data import functionality, including REDCap dictionary integration options and vocabulary collection selection tools; and (B) interactive term review and mapping selection interface. REDCap: Research Electronic Data Capture.

Meredith CB Adams, Matthew L Perkins, Cody Hudson, Vithal Madhira, Oguz Akbilgic, Da Ma, Robert W Hurley, Umit Topaloglu

J Med Internet Res 2025;27:e69004

Water, Sanitation, and Hygiene for Everyone Intervention Study: Protocol for a Controlled Before-and-After Trial

Water, Sanitation, and Hygiene for Everyone Intervention Study: Protocol for a Controlled Before-and-After Trial

(A) Map of Malawi with Chiradzulu District in red, and (B) Map of Chiradzulu District with W4 E study areas with TA Chitera (CLTS+CG group) in red, TA Ntchema (CLTS only) in yellow, and TA Nkalo (control) in green. CG: care group; CLTS: community-led total sanitation. The study design is a controlled before-and-after (CBA) trial with 2 treatment arms (each with 20 villages or clusters) and a control group (30 villages; Figure 2; Multimedia Appendix 1).

Kondwani Chidziwisano, Mindy Panulo, Clara MacLeod, Marcella Vigneri, Blessings White, Joseph Wells, Ian Ross, Tracy Morse, Robert Dreibelbis

JMIR Res Protoc 2025;14:e68280