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Additional screening measures will include (1) the Kessler Psychological Distress Scale, for anxiety and depressive symptoms; (2) a single-item measure of substance use within the last year that, if any item is endorsed, will trigger a more detailed drug and alcohol screening questionnaire; and (3) a single-item measure of trauma that, if endorsed, will trigger a more detailed trauma screening questionnaire.
JMIR Res Protoc 2025;14:e72786
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Build Back Better was developed by a multidisciplinary team with content adapted from a previously developed app, Head Gear, designed to prevent depression and anxiety and improve well-being among workers in male-dominated industries [18,22]. A randomized controlled trial of Head Gear with a large sample of workers showed that the app was effective in the prevention of depression and anxiety, as well as improving a range of MH and work-related outcomes [24,25].
JMIR Form Res 2025;9:e50995
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For the larger RCT, we determined a required sample size of 100 participants (50 per group) based on a minimum clinically important difference of 2.95 on the Pearlin Mastery Scale, an SD of 4.5, 90% power, and 5% α, using assumptions from a previous web-based caregiver intervention study [29].
J Med Internet Res 2025;27:e72141
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Generative AI–Powered Mental Wellness Chatbot for College Student Mental Wellness: Open Trial
This innovative approach positions Wayhaven as a unique tool for college students with elevated anxiety and depression symptoms, offering dynamic, evidence-based mental wellness support tailored to diverse needs. However, there is a need to evaluate its feasibility, acceptability, and preliminary effectiveness in a real-world setting.
JMIR Form Res 2025;9:e71923
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SCALE-UP II was a multisite, pragmatic clinical trial with patients randomized at the individual level in one of 2 study designs based on patients’ response to a SMS text message asking if the patient owned a smartphone, which was required for accessing the chatbot (Figure 1) [26].
J Med Internet Res 2025;27:e74145
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In "Using Wearable Devices and Speech Data for Personalized Machine Learning in Early Detection of Mental Disorders: Protocol for a Participatory Research Study" (JMIR Res Protoc 2023;12:e48210), the authors noted an error.
The following references:
32. Chen I-M, Lin P-H, Wu V-C, Wu C-S, Shan J-C, Chang S-S, et al. Suicide deaths among patients with end-stage renal disease receiving dialysis: a population-based retrospective cohort study of 64,000 patients in Taiwan. J Affect Disord. Feb 2018;227:7-10.
JMIR Res Protoc 2025;14:e78287
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The POWER project is a community-research partnership between the Resilient Sisterhood Project, a nonprofit organization that supports women of African descent on reproductive health issues; Resilient Sisterhood Project community members; Silent Spring Institute, a nonprofit organization that conducts environmental health research; and SMIs. We used strategic SMI communication to engage a large audience of Black women with EDC-related information.
J Med Internet Res 2025;27:e66128
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Our intervention incorporates 3 components of the CCM (Table 1) based on input from the CAB in a method that is convenient, acceptable, and interactive with adolescents on a daily basis.
JMIR Res Protoc 2025;14:e69903
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Social media platforms provide a relatively untapped, extensive source of public discussion from which health professionals can develop targeted interventions. A meta-analysis study analyzed social media pharmacovigilance studies and FDA reports and found that more adverse event discussions on social media corresponded to a higher hazard and faster drug product recall [12].
JMIR Infodemiology 2025;5:e73619
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It is hypothesized that catatonia is caused by either a dysfunction of gamma-aminobutyric acid (GABA) receptors or a deficit in GABA [6,7]. Current treatment options target this neurotransmitter imbalance.
Catatonia is a clinical syndrome characterized by a distinct constellation of psychomotor disturbances. A total of 2 subtypes have been described: retarded and excited [1,2].
JMIR Res Protoc 2025;14:e68356
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