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In the conceptual example illustrated in Figure 1, there are 4 sleep logs spanning 2 calendar days: C (day 0; 10:00 AM-noon), D (day 0; 2:00-3:30 PM), B (day 0; 10:00-11:30 PM), and A (day 1; 1:30-6:30 AM). To accurately compute sleep metrics, it is imperative to identify and include all primary sleep logs that fall within the primary sleep period, while distinguishing them from nonprimary sleep logs.
J Med Internet Res 2025;27:e71718
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It was administered in doses ranging between 0.01 and 0.1 g/kg, 3 times daily either orally or intravenously (equivalent to 2.4-24 g/d for an 80 kg patient). Among patients with schizophrenia and catatonia, approximately 30 participants, the study showed a reduction of catatonic symptoms ranging from 60% to 70%. Specifically, there were improvements in anxiety, agitation, and restlessness.
JMIR Res Protoc 2025;14:e68356
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Example screenshots of the Study Management and Retention Tool (SMa RT) web application, including the different Combine intervention content sections: (A) log in screen, (B) study timeline, (C) intervention content home screen, (D), health resources section, (E) frequently asked questions about pre-exposure prophylaxis.
This section includes the major time points of the study (baseline, month 6, month 12, month 18, and month 24). It allows participants to see upcoming and previously completed surveys.
JMIR Res Protoc 2025;14:e69540
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