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Biomechanical and Kinematic Gait Analysis in Lower Limb Amputees: Cross-Sectional Study

Biomechanical and Kinematic Gait Analysis in Lower Limb Amputees: Cross-Sectional Study

(A) Plantar pressure recording during static standing; (B) Inertial sensor placement at the S1 level for dynamic gait analysis. The 2 MWT was performed using a stopwatch and distance markers found in the facility. All equipment used for the assessments belonged to the Laboratory of Biomechanics and Rehabilitation of the Instituto Tecnológico Metropolitano (ITM), located in Medellín, Colombia.

Natali Olaya Mira, Luz Marina Gómez Hernández, Carolina Viloria Barragán, Manuela Monsalve Montes, Isabel Cristina Soto Cardona

JMIR Rehabil Assist Technol 2025;12:e67022

Sodium Oxybate as a Potential New Treatment for Catatonia in Patients With Depression, Bipolar Disorder, or a Psychotic Disorder: Protocol for a Randomized Controlled Trial

Sodium Oxybate as a Potential New Treatment for Catatonia in Patients With Depression, Bipolar Disorder, or a Psychotic Disorder: Protocol for a Randomized Controlled Trial

Sodium oxybate, the pharmacological agent used in this study, acts as a GABA-B receptor agonist and a precursor of GABA [24]. It was administered in doses ranging between 0.01 and 0.1 g/kg, 3 times daily either orally or intravenously (equivalent to 2.4-24 g/d for an 80 kg patient). Among patients with schizophrenia and catatonia, approximately 30 participants, the study showed a reduction of catatonic symptoms ranging from 60% to 70%.

Lilian Bot, Josine G van Mill, Laetitia J C A Smarius, Adriaan W Hoogendoorn, Bram W C Storosum, Christiaan H Vinkers, Gabriel E Jacobs, Gert Jan Lammers, Hanna M Heller, Jantine C A Colen-de Koning, Joris J B van der Vlugt, Marloes S Oudijn, Martijn S van Noorden, Pierre M Bet, Rolf Fronczek, Heleen S van der Heijden, Sjors M M Lange, Ysbrand D van der Werf, Eric R van Exel

JMIR Res Protoc 2025;14:e68356

Associations Between Daily Symptoms and Pain Flares in Rheumatoid Arthritis: Case-Crossover mHealth Study

Associations Between Daily Symptoms and Pain Flares in Rheumatoid Arthritis: Case-Crossover mHealth Study

(B) Two scenarios of exclusion. Left: the onset (day 4) meets the definition, but the pain severity is at the personal median pain level, conflicting with the criterion for the end of a pain flare. Right: 2 flare onsets (days 2 and 4) meet the definition but end on the same day (day 5). The second onset (day 4) is removed to avoid double counting. In addition to identifying pain flares by their severity, we examined their residual impact in the postflare phase.

Ting-Chen Chloe Hsu, Belay B Yimer, Pauline Whelan, Christopher J Armitage, Katie Druce, John McBeth

JMIR Mhealth Uhealth 2025;13:e64889