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Efficacy of Fuzheng Quxie Formula Against Postoperative Metastasis of Lung Cancer in Stage IIA-IIIA With Negative Driver Genes: Protocol for a Multicenter, Double-Blind, Randomized Controlled Trial

Efficacy of Fuzheng Quxie Formula Against Postoperative Metastasis of Lung Cancer in Stage IIA-IIIA With Negative Driver Genes: Protocol for a Multicenter, Double-Blind, Randomized Controlled Trial

In this formula, Sheng Huang Qi, Fu Ling, Bai Zhu tonify spleen and stomach to “strengthen earth to generate metal;” Bei Sha Shen, Tian Dong, Mai Dong nourishes yin and moistens the lungs; Hai Zao, Xia Ku Cao, Kun Bu, which soften and resolve hard mass, and Bai Hua She She Cao, Shi Jian Chaun, Shi Shang Bai, which clear heat, detoxifying to disperse nodules. This formula is primarily indicated for patients with lung cancer presenting with clinical manifestations of qi and yin deficiency syndrome.

Fan Xu, Yun Yang, Yinbin Luo, Bin Luo, Jialiang Yao, Yiyang Zhou, Minghua Li, Jianchun Wu, Wenfei Shi, Lei Jiang, Qian Huang, Wentao Fang, Zhihong Fang, Yan Li, Jianhui Tian

JMIR Res Protoc 2025;14:e66342