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The Measurement of Vital Signs in Pediatric Patients by Lifelight Software in Comparison to the Standard of Care: Protocol for the VISION-Junior Observational Study

The Measurement of Vital Signs in Pediatric Patients by Lifelight Software in Comparison to the Standard of Care: Protocol for the VISION-Junior Observational Study

Photoplethysmography (PPG) is an optical measurement technique that records changes in the light reflected from the skin surface due to volumetric changes in the facial blood vessels; small variations in perfusion provide valuable information about the cardiovascular system [9]. PPG has been used to measure PR [10,11], oxygen saturation [12], BP [13,14], and RR [10,15] and to detect atrial fibrillation [16].

Gauri Misra, Simon Wegerif, Louise Fairlie, Melissa Kapoor, James Fok, Gemma Salt, Jay Halbert, Ian Maconochie, Niall Mullen

JMIR Res Protoc 2025;14:e58334

Assessment of the Sensitivity of a Smartphone App to Assist Patients in the Identification of Stroke and Myocardial Infarction: Cross-Sectional Study

Assessment of the Sensitivity of a Smartphone App to Assist Patients in the Identification of Stroke and Myocardial Infarction: Cross-Sectional Study

We estimated that a sample size of 200 patients was sufficient to provide power to detect small to medium effect sizes, ensuring robust statistical analysis of sensitivity of the app. In addition, this number was deemed feasible for a single-center study within the constraints of the available budget and study period. The sampling method was consecutive sampling.

Amar Dhand, Rama Mangipudi, Anubodh S Varshney, Jonathan R Crowe, Andria L Ford, Nancy K Sweitzer, Min Shin, Samuel Tate, Haissam Haddad, Michael E Kelly, James Muller, Jay S Shavadia

JMIR Form Res 2025;9:e60465

Exploring Older Adult Cancer Survivors’ Digital Information Needs: Qualitative Pilot Study

Exploring Older Adult Cancer Survivors’ Digital Information Needs: Qualitative Pilot Study

Further, although the participants represented geographic diversity, all identified as White, spoke English, and had postsecondary education; thus, this small, nonrepresentative sample may have reduced the richness of the data and the ability to achieve data saturation. Questions regarding diversity will also be added to the upcoming survey. Overall, this pilot study confirmed the utility of DHTs in enhancing the connection of older adult cancer survivors to health care.

Lorelei Newton, Helen Monkman, Claire Fullerton

JMIR Cancer 2025;11:e59391

Identifying the Minimal Clinically Important Difference in Emotion Regulation Among Youth Using the JoyPop App: Survey Study

Identifying the Minimal Clinically Important Difference in Emotion Regulation Among Youth Using the JoyPop App: Survey Study

Given the pilot study’s small sample size and attrition by time 3, we used time-1 and time-2 data for calculating the MCID. The Global Rating of Change Scale (GRCS) is a single-item measure assessing the degree of change individuals felt occurred during or after an intervention [6]. The GRCS asked participants “As a result of using the Joy Pop app, has your ability to understand and manage your emotions been...”

Jaidyn Charlton, Ishaq Malik, Angela M Ashley, Amanda Newton, Elaine Toombs, Fred Schmidt, Janine V Olthuis, Kristine Stasiuk, Tina Bobinski, Aislin Mushquash

JMIR Form Res 2025;9:e64483

Preliminary Effectiveness of a Telehealth-Delivered Exercise Program in Older Adults Living With and Beyond Cancer: Retrospective Study

Preliminary Effectiveness of a Telehealth-Delivered Exercise Program in Older Adults Living With and Beyond Cancer: Retrospective Study

A Cohen d of 0.2 was considered a small effect, 0.5 was considered medium, and 0.8 was considered large. For categorical outcomes mean change scores and 95% CIs were calculated to determine change across the intervention. All data were analyzed in SPSS (version 29.0; IBM Corp). The protocol and waiver of informed consent was approved by the University of Utah Institutional Review Board (IRB_00072431) in accordance with the Declaration of Helsinki.

Emily R Dunston, Sonal Oza, Yang Bai, Maria Newton, Leslie Podlog, Kish Larson, Darren Walker, Rebecca W Zingg, Pamela A Hansen, Adriana M Coletta

JMIR Cancer 2025;11:e56718

Economics and Equity of Large Language Models: Health Care Perspective

Economics and Equity of Large Language Models: Health Care Perspective

It is important to note that measurement bias may accentuate validation bias because validation at small sample sizes can be statistically challenging. Label bias may be a result of surrogate variables substituting the actual health care outcomes of interest. Modeling bias is attributed to the biased results generated by a specific model. Computational and statistical biases can be a result of inadequate representation of select groups and populations in the given data.

Radha Nagarajan, Midori Kondo, Franz Salas, Emre Sezgin, Yuan Yao, Vanessa Klotzman, Sandip A Godambe, Naqi Khan, Alfonso Limon, Graham Stephenson, Sharief Taraman, Nephi Walton, Louis Ehwerhemuepha, Jay Pandit, Deepti Pandita, Michael Weiss, Charles Golden, Adam Gold, John Henderson, Angela Shippy, Leo Anthony Celi, William R Hogan, Eric K Oermann, Terence Sanger, Steven Martel

J Med Internet Res 2024;26:e64226

Body Positivity, Physical Health, and Emotional Well-Being Discourse on Social Media: Content Analysis of Lizzo’s Instagram

Body Positivity, Physical Health, and Emotional Well-Being Discourse on Social Media: Content Analysis of Lizzo’s Instagram

In addition to Lizzo’s original posts, Instagram users’ comments and replies to those comments were also coded and small modifications were made to the original coding scheme to improve clarity and increase consistency between coders. Following the training sessions, 1 round of pilot coding was conducted using the first 10 Lizzo Instagram posts, including the associated user comments and replies, in the sample. Posts were coded by 2 coders independently.

Stephanie L Albert, Rachel E Massar, Omni Cassidy, Kayla Fennelly, Melanie Jay, Philip M Massey, Marie A Bragg

JMIR Form Res 2024;8:e60541

Practical Aspects of Using Large Language Models to Screen Abstracts for Cardiovascular Drug Development: Cross-Sectional Study

Practical Aspects of Using Large Language Models to Screen Abstracts for Cardiovascular Drug Development: Cross-Sectional Study

Limitations include a small cardiovascular dataset leveraging proprietary LLMs and only a subset of available optimization techniques. Future efforts must engage diverse scientific communities; develop guardrails to ensure safe and responsible LLM use; and apply data-driven best practices that generalize, optimize, and validate LLM applications and their impact on patients with cardiovascular disease.

Jay G Ronquillo, Jamie Ye, Donal Gorman, Adina R Lemeshow, Stephen J Watt

JMIR Med Inform 2024;12:e64143