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Population-Based Digital Health Interventions to Deliver at-Home COVID-19 Testing: SCALE-UP II Randomized Clinical Trial

Reach-Accept testing in the Chatbot arm was lower than in SMS text messaging (174/1051, 16.6% vs 555/1066, 52.1%; a RR 0.317, 98.33% CI 0.27‐0.38; P Reach-Accept testing was higher among participants messaged every 10 days vs every 30 days (860/15,717, 5.5% vs 752/15,722, 4.8%; a RR 1.144, 97.5% CI 1.03‐1.28; P=.01; Table 2), and lower if the participants were offered access to PN compared with those in the no PN condition (680/15,718, 4.3% vs 932/15,721, 5.9%; a RR 0.729, 97.5% CI 0.65‐0.81; P Out of 2117 participants

Guilherme Del Fiol, Tatyana V Kuzmenko, Brian Orleans, Jonathan J Chipman, Tom Greene, Ray Meads, Kimberly A Kaphingst, Bryan Gibson, Kensaku Kawamoto, Andy J King, Tracey Siaperas, Shlisa Hughes, Alan Pruhs, Courtney Pariera Dinkins, Cho Y Lam, Joni H Pierce, Ryzen Benson, Emerson P Borsato, Ryan C Cornia, Leticia Stevens, Richard L Bradshaw, Chelsey R Schlechter, David W Wetter

J Med Internet Res 2025;27:e74145

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Using Natural Language Processing to Identify Symptomatic Adverse Events in Pediatric Oncology: Tutorial for Clinician Researchers

Clifton P Thornton, Maryam Daniali, Lei Wang, Spandana Makeneni, Allison Barz Leahy

JMIR Bioinform Biotech 2025;6:e70751

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Improving Large Language Models’ Summarization Accuracy by Adding Highlights to Discharge Notes: Comparative Evaluation

The Fisher exact test yielded P=.01, indicating a statistically significant difference. As shown in Table 2, the average word count of the original notes was 320 words, and the average length reduction of the H-summaries and U-summaries was 22% (SD 15%) and 23% (SD 15%) words, respectively. A negative number for length reduction in Table 2 indicates that the summary generated had more words than the original text. In our analysis, we identified 3 instances of false information in U-summaries.

Mahshad Koohi Habibi Dehkordi, Yehoshua Perl, Fadi P Deek, Zhe He, Vipina K Keloth, Hao Liu, Gai Elhanan, Andrew J Einstein

JMIR Med Inform 2025;13:e66476

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Evaluation of a Virtual Home Health Heart Failure Program: Mixed Methods Study

The median scores at baseline and follow-up for total distress (1.50, IQR 0-7 and 0.0, IQR 0-8; z=–2.42; P Of the 34 (85%) patients who responded to the PREMs questionnaire, all (100%) responded “always” or “mostly” to questions about their treatment and care (Table 3). Most patients (94%) responded that their views and concerns were always listened to. Twenty-six (76%) patients responded that they always knew how to recognize HF or heart attack symptoms and what to do next.

Nilufeur McKay, Rosemary Saunders, Helene Metcalfe, Sue Robinson, Peter Palamara, Kellie Steer, Jeannie Yoo, Miles Ranogajec, Lisa Whitehead, Beverley Ewens

JMIR Cardio 2025;9:e64877

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Impact of Ecological Momentary Assessment Participation on Short-Term Smoking Cessation: quitSTART Ecological Momentary Assessment Incentivization Randomized Trial

Mean EMAs completed in the incentivized arm was 13.3 (SD 11.2, range 0‐40, average completion rate of 31.7% out of 42 total EMA prompts) and 4.7 (SD 5.8, range 0‐28, average completion rate of 11.2% out of 42 total EMA prompts) in the nonincentivized arm (P Smoking cessation outcomes overall and by group. a EMA: ecological momentary assessment.

Kara P Wiseman, Alex Budenz, Leeann Siegel, Yvonne M Prutzman

J Med Internet Res 2025;27:e67630

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Facilitators and Challenges to Adoption of a Digital Health Tool for Opioid Use Disorder Treatment in Primary Care: Mixed Methods Study

A Bonferroni correction was applied to all P values by multiplying each P value by 4, the number of tests conducted, to correct for multiple comparisons; a P value less than .05 was considered statistically significant after correction. Timelines of OARS use were also described for MOUD providers and case managers. All analyses were conducted in R (version 4.2.1; R Foundation for Statistical Computing). All qualitative data were analyzed using a coding reliability thematic analysis approach [16].

Omar Nieto, Allison D Rosen, Mariah M Kalmin, Li Li, Steven J Shoptaw, Steven P Jenkins, Zahra Zarei Ardestani, Bengisu Tulu

J Med Internet Res 2025;27:e69953

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Association of Perceived Xingfu With Health-Related and Socioeconomic Factors Among Hong Kong Chinese Adults: Cross-Sectional Study Using a Novel Single-Item Tool

All P values for Pearson correlation coefficients b PSS-4: Perceived Stress Scale-4. c ACC: adversity coping capability. d PHQ-4: Patient Health Questionnaire-4. e Not applicable. Figure 1 shows the distribution of perceived xingfu and happiness scores. As both perceived xingfu and happiness peaked at scores of 7 (22%) and 8 (23%); therefore, perceived xingfu ≥7 was classified as high perceived xingfu in the logistic regression model.

Katherine Y P Sze, Sai Yin Ho, Agnes Yuen Kwan Lai, Jing Jia, Heng Xu, Shirley Man Man Sit, Tai Hing Lam, Man Ping Wang