<?xml version="1.0" encoding="UTF-8"?><!DOCTYPE article PUBLIC "-//NLM//DTD Journal Publishing DTD v2.0 20040830//EN" "journalpublishing.dtd"><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" dtd-version="2.0" xml:lang="en" article-type="research-article"><front><journal-meta><journal-id journal-id-type="nlm-ta">JMIR Aging</journal-id><journal-id journal-id-type="publisher-id">aging</journal-id><journal-id journal-id-type="index">31</journal-id><journal-title>JMIR Aging</journal-title><abbrev-journal-title>JMIR Aging</abbrev-journal-title><issn pub-type="epub">2561-7605</issn><publisher><publisher-name>JMIR Publications</publisher-name><publisher-loc>Toronto, Canada</publisher-loc></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">v9i1e77190</article-id><article-id pub-id-type="doi">10.2196/77190</article-id><article-categories><subj-group subj-group-type="heading"><subject>Original Paper</subject></subj-group></article-categories><title-group><article-title>Evaluation of a Gamification-Based Intervention to Enhance Intergenerational Communication: Pre-Post Mixed Methods Evaluation</article-title></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name name-style="western"><surname>Wong</surname><given-names>Eliza Lai-Yi</given-names></name><degrees>PhD</degrees><xref ref-type="aff" rid="aff1">1</xref><xref ref-type="aff" rid="aff2">2</xref></contrib><contrib contrib-type="author"><name name-style="western"><surname>Ng</surname><given-names>Clement Cheuk Wai</given-names></name><degrees>PhD</degrees><xref ref-type="aff" rid="aff2">2</xref></contrib><contrib contrib-type="author"><name name-style="western"><surname>Wang</surname><given-names>Dorothy Yingxuan</given-names></name><degrees>PhD</degrees><xref ref-type="aff" rid="aff1">1</xref><xref ref-type="aff" rid="aff2">2</xref></contrib><contrib contrib-type="author"><name name-style="western"><surname>Wong</surname><given-names>Carol Ka Po</given-names></name><degrees>MPH</degrees><xref ref-type="aff" rid="aff2">2</xref></contrib><contrib contrib-type="author"><name name-style="western"><surname>Lui</surname><given-names>Shirley Shuk Kuen</given-names></name><degrees>BSc</degrees><xref ref-type="aff" rid="aff2">2</xref></contrib><contrib contrib-type="author"><name name-style="western"><surname>Cheung</surname><given-names>Annie Wai-Ling</given-names></name><degrees>MPhil</degrees><xref ref-type="aff" rid="aff1">1</xref><xref ref-type="aff" rid="aff2">2</xref></contrib><contrib contrib-type="author"><name name-style="western"><surname>Yeoh</surname><given-names>Eng-kiong</given-names></name><degrees>MBBS</degrees><xref ref-type="aff" rid="aff1">1</xref><xref ref-type="aff" rid="aff2">2</xref></contrib></contrib-group><aff id="aff1"><institution>Centre for Health Systems and Policy Research, The Jockey Club School of Public Health and Primary Care, Faculty of Medicine, The Chinese University of Hong Kong</institution><addr-line>Room 418, School of Public Health Building, Prince of Wales Hospital, Ngan Shing St</addr-line><addr-line>Sha Tin</addr-line><country>China (Hong Kong)</country></aff><aff id="aff2"><institution>The Jockey Club School of Public Health and Primary Care, Faculty of Medicine, The Chinese University of Hong Kong</institution><addr-line>Hong Kong</addr-line><country>China (Hong Kong)</country></aff><contrib-group><contrib contrib-type="editor"><name name-style="western"><surname>Jiang</surname><given-names>Yun</given-names></name></contrib></contrib-group><contrib-group><contrib contrib-type="reviewer"><name name-style="western"><surname>Janssen</surname><given-names>Jeroen</given-names></name></contrib><contrib contrib-type="reviewer"><name name-style="western"><surname>Jordan-Marsh</surname><given-names>Maryalice</given-names></name></contrib><contrib contrib-type="reviewer"><name name-style="western"><surname>Lima</surname><given-names>Tiago</given-names></name></contrib></contrib-group><author-notes><corresp>Correspondence to Eliza Lai-Yi Wong, PhD, Centre for Health Systems and Policy Research, The Jockey Club School of Public Health and Primary Care, Faculty of Medicine, The Chinese University of Hong Kong, Room 418, School of Public Health Building, Prince of Wales Hospital, Ngan Shing St, Sha Tin, China (Hong Kong), 852 22528772; <email>lywong@cuhk.edu.hk</email></corresp></author-notes><pub-date pub-type="collection"><year>2026</year></pub-date><pub-date pub-type="epub"><day>31</day><month>7</month><year>2026</year></pub-date><volume>9</volume><elocation-id>e77190</elocation-id><history><date date-type="received"><day>09</day><month>05</month><year>2025</year></date><date date-type="rev-recd"><day>29</day><month>05</month><year>2026</year></date><date date-type="accepted"><day>04</day><month>06</month><year>2026</year></date></history><copyright-statement>&#x00A9; Eliza Lai-Yi Wong, Clement Cheuk Wai Ng, Dorothy Yingxuan Wang, Carol Ka Po Wong, Shirley Shuk Kuen Lui, Annie Wai-Ling Cheung, Eng-kiong Yeoh. Originally published in JMIR Aging (<ext-link ext-link-type="uri" xlink:href="https://aging.jmir.org">https://aging.jmir.org</ext-link>), 31.7.2026. </copyright-statement><copyright-year>2026</copyright-year><license license-type="open-access" xlink:href="https://creativecommons.org/licenses/by/4.0/"><p>This is an open-access article distributed under the terms of the Creative Commons Attribution License (<ext-link ext-link-type="uri" xlink:href="https://creativecommons.org/licenses/by/4.0/">https://creativecommons.org/licenses/by/4.0/</ext-link>), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in JMIR Aging, is properly cited. The complete bibliographic information, a link to the original publication on <ext-link ext-link-type="uri" xlink:href="https://aging.jmir.org">https://aging.jmir.org</ext-link>, as well as this copyright and license information must be included.</p></license><self-uri xlink:type="simple" xlink:href="https://aging.jmir.org/2026/1/e77190"/><abstract><sec><title>Background</title><p>Intergenerational communication has been recognized as a key factor in enhancing social connections among older adults by improving the quality of interactions, which is a crucial component of healthy aging. However, effective interventions to foster intergenerational communication and engagement remain scarce at this stage.</p></sec><sec><title>Objective</title><p>This study examined the effects of a gamification intervention for intergenerational dialogue on intergenerational communication and health-related capacity across 3 age cohorts and further analyzed the differential impacts of intervention characteristics on the game experience, in terms of satisfaction and engagement.</p></sec><sec sec-type="methods"><title>Methods</title><p>A 2-stage exploratory method was adopted with a cocreation approach to develop a theoretical framework of intergenerational dialogue for the gamification-based intervention, the Healthy Aging in Dialogue Tabletop Game, followed by a mixed methods study involving pre- and postintervention surveys and qualitative interviews to evaluate the effectiveness of the intervention in the young (aged 18&#x2010;39 years), middle-aged (aged 40&#x2010;64 years), and older adult (aged &#x2265;65 years) groups. Intergenerational communication was assessed using tools measuring satisfaction and competence, whereas health-related capacity was evaluated using health literacy and patient enablement tools.</p></sec><sec sec-type="results"><title>Results</title><p>A total of 68 respondents completed the intervention and evaluation, with 23, 14, and 31 respondents in the young, middle-aged, and older adult groups, respectively. This intergenerational intervention yielded notable benefits in intergenerational communication satisfaction (Cohen <italic>d</italic>=0.745), communication competence (Cohen <italic>d</italic>=0.377), and health literacy (Cohen <italic>d</italic>=0.409), especially among older adults. Patient enablement was significantly higher in older adults (mean score 6.10, SD 2.18) than in young adults (mean score 4.22) (<italic>P</italic>=.04). In addition, this study highlighted the importance of leveraging gamification to enhance intergenerational communication and engagement, ultimately combating social isolation among older adults.</p></sec><sec sec-type="conclusions"><title>Conclusions</title><p>The intergenerational dialogue tabletop game provided an enjoyable platform for cross-generational dialogue and enhanced each age group&#x2019;s communication competence, allowing participants to contribute and learn from one another. The findings provide additional evidence for aging research and shed light on approaches to foster social interaction and connection, thereby promoting health and active aging.</p></sec></abstract><kwd-group><kwd>intergenerational communication</kwd><kwd>health</kwd><kwd>gamification intervention</kwd><kwd>social isolation</kwd><kwd>social connection</kwd><kwd>aging</kwd></kwd-group></article-meta></front><body><sec id="s1" sec-type="intro"><title>Introduction</title><p>Rapid technological advancement, urbanization, and aging have significantly reshaped social dynamics, family structures, and community engagement, leading to fewer face-to-face interactions. Evidence shows that digital communication increasingly replaces face-to-face interactions [<xref ref-type="bibr" rid="ref1">1</xref>], with individuals often withdrawing from in-person contact due to technology use and fast-paced lifestyles [<xref ref-type="bibr" rid="ref2">2</xref>]. These societal shifts, combined with changing family structures linked to population aging, contribute to reduced intergenerational engagement and weakened community ties [<xref ref-type="bibr" rid="ref3">3</xref>]. Among these transformations, social isolation has emerged as a critical concern since the 1990 s due to its profound implications across levels of society, including individuals, families, workplaces, disease groups, and broader society [<xref ref-type="bibr" rid="ref4">4</xref>,<xref ref-type="bibr" rid="ref5">5</xref>]. Social isolation is defined as the objective absence or insufficiency of meaningful and sustained communication [<xref ref-type="bibr" rid="ref6">6</xref>], reflected in having too few interactions with others. It has become a priority global health issue recognized by the World Health Organization (WHO) and the United Nations, with an estimated 25% of older people and 15% of adolescents experiencing social isolation [<xref ref-type="bibr" rid="ref7">7</xref>] because it has been linked to numerous adverse outcomes documented by a growing body of evidence, such as mental health decline, depression, dementia, cardiovascular disease, stroke, falls, reduced quality of life, hindered active aging, and increased mortality rates [<xref ref-type="bibr" rid="ref8">8</xref>,<xref ref-type="bibr" rid="ref9">9</xref>]. Our preliminary work shows that prevailing circumstances, such as pandemics, climate change, policies, family crises, and health deterioration, further intensify social isolation [<xref ref-type="bibr" rid="ref10">10</xref>,<xref ref-type="bibr" rid="ref11">11</xref>]. Loneliness, by contrast, represents a distressing feeling arising from a perceived and experienced lack of interaction [<xref ref-type="bibr" rid="ref6">6</xref>]. Although social isolation is an objective form of social disconnection, whereas loneliness is a subjective form, they are strongly related [<xref ref-type="bibr" rid="ref12">12</xref>], and both forms of disconnection carry significant health risks [<xref ref-type="bibr" rid="ref7">7</xref>,<xref ref-type="bibr" rid="ref13">13</xref>].</p><p>Many intergenerational programs have been shown to mitigate social isolation and loneliness by strengthening cross-age communication and expanding older adults&#x2019; social networks [<xref ref-type="bibr" rid="ref14">14</xref>-<xref ref-type="bibr" rid="ref16">16</xref>]. Intergenerational communication, defined as the exchange of ideas, values, and experiences between different age groups [<xref ref-type="bibr" rid="ref17">17</xref>], has been recognized as a key factor in addressing social isolation by fostering mutual understanding and improving the quality of intergenerational interactions within an intergenerational program [<xref ref-type="bibr" rid="ref15">15</xref>]. Existing intergenerational programs mainly focus on structured connections and individual-based interactions (eg, one-way storytelling, companionship for social and health support), and community-based activities (eg, group-based activities related to arts, gardening, physical activity, cooking, digital games, volunteering, and neighborhood support) [<xref ref-type="bibr" rid="ref14">14</xref>-<xref ref-type="bibr" rid="ref16">16</xref>]. The conversation-based program remains limited, despite being the central component of social connection. Without engaging in dialogue topics or accommodating communication practices, social isolation can be perpetuated. Key components of communication include listening, observing verbal and nonverbal cues, and expressing thoughts and emotions through both verbal and nonverbal channels [<xref ref-type="bibr" rid="ref18">18</xref>], all of which are essential for achieving mutual understanding, building a trusting relationship, and fostering an empathetic and caring environment [<xref ref-type="bibr" rid="ref19">19</xref>]. When individuals lack adequate communication skills or have limited exposure to diverse conversational partners, they may struggle to accurately interpret others&#x2019; cues or express themselves effectively. This is particularly evident in intergenerational contexts. Giles and Gasiorek [<xref ref-type="bibr" rid="ref20">20</xref>] found that younger adults often overaccommodate older individuals through overprotection, whereas older adults tend to underaccommodate younger individuals by voicing harsh criticisms of their generation. A lack of intergenerational understanding may deepen generational divides, leading to age stereotypes that may contribute to nonaccommodation [<xref ref-type="bibr" rid="ref21">21</xref>]. Without engaging in dialogue topics or practicing accommodating communication strategies, social isolation can be reinforced. Furthermore, most programs are time-limited, and older adults often lose access to the platforms and opportunities that enable ongoing interaction with younger people, leading to a decline in sustained engagement.</p><p>Given that the intervention was explicitly designed to structure and enhance intergenerational dialogue, this study focuses on proximal communication outcomes, specifically communication competence and communication satisfaction, as direct indicators of interaction quality. Although social isolation and loneliness motivate this work as broader public health concerns, these outcomes are conceptualized as distal and likely to emerge through sustained improvements in the communication process over time. Accordingly, this study evaluates the effects of the intervention on communication-related outcomes, providing a necessary foundation for future research to examine downstream impacts on social isolation and loneliness. This paper addresses this gap by developing a structured intergenerational tabletop game as a repeatable, low-cost platform that provides guided conversation topics and supports the four key communication components as intervention mechanisms that facilitate meaningful interaction beyond formal programs: guided conversational exchange; shared problem-solving through cooperative tasks; perspective-taking and mutual learning across generations; and opportunities to practice and build confidence in communication competence. Additionally, the intervention embedded health content to enhance health literacy and enablement, supporting participants&#x2019; capacity to sustain and apply communication gains, as poor health literacy has been recognized by the WHO as a key driver of social isolation and a diminished capacity for social participation [<xref ref-type="bibr" rid="ref3">3</xref>].</p></sec><sec id="s2" sec-type="methods"><title>Methods</title><sec id="s2-1"><title>Overview</title><p>A 2-stage exploratory method was used to develop intergenerational dialogue prototypes for the gamification-based intervention and to evaluate its effectiveness on the communication process. Gamification was adopted to incorporate game-based intervention elements such as points, leaderboards, and badges into a nongame context to enhance the engagement experience [<xref ref-type="bibr" rid="ref22">22</xref>]. This study investigated the effectiveness of the &#x201C;Healthy Aging in Dialogue Card Game&#x201D; on intergenerational communication, health, and game experience in three age cohorts: 18&#x2010;39 years, 40&#x2010;64 years, and &#x2265;65 years. The objectives were to evaluate communication skills (communication competence and satisfaction), health literacy, self-efficacy, and engagement in the game (fun, encouragement to communicate, health knowledge building, and satisfaction) across age groups in the pre- and postsurveys.</p></sec><sec id="s2-2"><title>Study Population</title><sec id="s2-2-1"><title>Overview</title><p>Participants who were Hong Kong residents and spoke Cantonese as their native language were eligible for the study, while those without the cognitive capacity to provide consent were excluded. Recruitment of young adults aged 18&#x2010;39 years and middle-aged adults aged 40&#x2010;64 years was conducted via mass mailings at universities and social media, including Facebook (Meta Platforms, Inc) and Instagram (Meta Platforms, Inc). Older adults aged 65 years or older were recruited by nongovernmental organizations via flyers and a multicommunity-center approach.</p></sec><sec id="s2-2-2"><title>Stage 1: Cocreation and Prototype Development for Intergenerational Dialogue</title><p>The development of the intergenerational dialogue intervention followed the revised Medical Research Council guidance for complex interventions [<xref ref-type="bibr" rid="ref23">23</xref>], with an emphasis on theory-driven design, stakeholder input, and iterative refinement. A 4-member cocreation team, comprising an academic with training in nursing and public health (ELYW), a social worker, a public health practitioner (CKPW), and 1 potential end user (SSKL), led the multistage development process.</p></sec><sec id="s2-2-3"><title>Theoretical Framework: Listening, Observing, Understanding, and Expression</title><p>The intervention was theoretically informed by the Listening, Observing, Understanding, and Expression (LOUE) framework, which integrates core verbal, nonverbal, and emotional communication processes [<xref ref-type="bibr" rid="ref18">18</xref>]. LOUE was selected because it aligns closely with the goals of intergenerational dialogue, where effective communication depends not only on verbal exchange but also on emotional attunement, reciprocal self-disclosure, and perspective-taking. Specifically, active listening and empathic engagement are fundamental to building understanding and trust in interpersonal communication [<xref ref-type="bibr" rid="ref24">24</xref>], while emotional attunement enables individuals to perceive and respond sensitively to others&#x2019; affective states [<xref ref-type="bibr" rid="ref25">25</xref>]. Perspective-taking further supports interpersonal connection by allowing individuals to understand others&#x2019; thoughts and viewpoints, and reciprocal self-disclosure fosters relational closeness and social bonding [<xref ref-type="bibr" rid="ref26">26</xref>]. In this study, LOUE served as a design framework to guide the generation, classification, and structuring of dialogue prompts, ensuring that gameplay systematically exercises these 4 communication skills.</p></sec><sec id="s2-2-4"><title>Identification of Dialogue Categories and Topic Generation</title><p>At the identification stage, the cocreation team reviewed evidence from intergenerational communication and health promotion programs [<xref ref-type="bibr" rid="ref27">27</xref>,<xref ref-type="bibr" rid="ref28">28</xref>] and collaboratively identified recurring thematic domains relevant to everyday intergenerational interactions. Through iterative discussion and clustering of draft prompts, six dialogue categories, defined as thematic groupings of communication prompts, were agreed upon: (1) Speak and Motion, (2) Life Experience, (3) Life Values, (4) Health Literacy, (5) Interpersonal Relationship, and (6) Digital Literacy (<xref ref-type="fig" rid="figure1">Figure 1</xref>). Building on these categories, the team generated an initial pool of conversation prompts and refined them based on relevance, clarity, and suitability for group dialogue. This process resulted in 77 dialogue topics, which were further refined through a design review to ensure balanced representation across categories and suitability for delivery in a game-based format.</p><fig position="float" id="figure1"><label>Figure 1.</label><caption><p>Theoretical framework of the Healthy Aging in Dialogue intervention. MTR: metro.</p></caption><graphic alt-version="no" mimetype="image" position="float" xlink:type="simple" xlink:href="aging_v9i1e77190_fig01.png"/></fig></sec><sec id="s2-2-5"><title>Operationalization as Mission Cards and Intervention Structure</title><p>The 77 dialogue topics were operationalized as mission cards, each containing a structured prompt designed to elicit turn-taking dialogue and reflection. Mission cards were evenly distributed across the 6 dialogue categories. Each card primarily targeted 1 LOUE dimension (eg, listening or expression), while still engaging all 4 communication skills through interaction and response. This structure ensured that each game turn focused on a specific topic while cumulatively strengthening intergenerational communication competencies.</p></sec><sec id="s2-2-6"><title>Gamified Tabletop Intervention Design</title><p>These mission cards were embedded within a gamified tabletop board game titled the &#x201C;Healthy Aging in Dialogue Tabletop Game.&#x201D; The intervention consists of players taking turns drawing mission cards, completing dialogue tasks, and accumulating points through participation rather than correct performance. Each player selects a chess piece at the start of the game to represent equal participation and balanced turn-taking, highlighting intergenerational communication as a reciprocal process.</p><p>Gamification elements were incorporated to enhance engagement, self-expression, and motivation [<xref ref-type="bibr" rid="ref29">29</xref>]. A point-based system (1&#x2010;3 points, reflecting increasing depth of conversational engagement, ranging from factual exchanges to meaning-making and reflective discussion) was used. Evidence suggests that such gamification strategies can promote interaction, maintain autonomy, and sustain engagement [<xref ref-type="bibr" rid="ref29">29</xref>,<xref ref-type="bibr" rid="ref30">30</xref>]. Importantly, 58 of 77 (75%) mission cards require the active involvement of multiple players, such as inviting adjacent or all players to respond, thereby encouraging listening, observing others&#x2019; perspectives, and shared reflection [<xref ref-type="bibr" rid="ref31">31</xref>-<xref ref-type="bibr" rid="ref33">33</xref>].</p></sec><sec id="s2-2-7"><title>Game Format and Play Procedure</title><p>The intervention is designed for 3&#x2010;6 players aged 11 years or above, with each group comprising at least 1 young adult (18&#x2010;39 years), 1 middle-aged adult (40&#x2010;64 years), and 1 older adult (&#x2265;65 years). A typical game session lasts 20&#x2010;30 minutes, or until a preset endpoint is reached, to maintain attention and prevent conversational dominance. Players take turns clockwise, draw mission cards, and complete tasks within approximately 1&#x2010;2 minutes per turn. There are no correct answers, and judgmental feedback is discouraged to maintain a respectful and inclusive dialogue environment. Details of the game setup and rules are provided in <xref ref-type="fig" rid="figure2">Figure 2</xref>.</p><fig position="float" id="figure2"><label>Figure 2.</label><caption><p>Healthy Aging in Dialogue Tabletop Game.</p></caption><graphic alt-version="no" mimetype="image" position="float" xlink:type="simple" xlink:href="aging_v9i1e77190_fig02.png"/></fig></sec><sec id="s2-2-8"><title>Stage 2: Mixed Methods Evaluation of the Effectiveness of the Gamification-Based Intervention</title><p>A mixed methods study method consisting of a 2-phase longitudinal survey and follow-up qualitative sessions involving focus group or individual interviews was conducted on-site to evaluate the effectiveness of the gamification-based intervention&#x2014;the Healthy Aging in Dialogue Tabletop Game. Before the intervention, all participants completed the baseline questionnaires independently or with assistance from a trained research assistant. Immediately after the intervention, they completed the follow-up questionnaire. A minimum sample size of 63 was recommended to detect a medium effect size of 0.5 at a significance level of .05 and statistical power of 80%, with the assumed SD of 1 [<xref ref-type="bibr" rid="ref34">34</xref>]. The questionnaire consisted of the following four sections: (1) intergenerational communication, (2) health-related capacity, (3) game experience (postintervention only), and (4) demographics (baseline only).</p></sec></sec><sec id="s2-3"><title>Primary Outcome Measure</title><p>Intergenerational communication was assessed in terms of communication satisfaction and communication competence. Communication satisfaction was assessed using four conceptually relevant items selected from Hecht Interpersonal Communication Satisfaction Inventory [<xref ref-type="bibr" rid="ref35">35</xref>]. The item &#x201C;I felt I could talk about topic with the other person&#x201D; was modified from &#x201C;anything&#x201D; to &#x201C;topic&#x201D; to fit the structured dialogue context, while the remaining three items&#x2014;&#x201C;I am generally satisfied with the conversations,&#x201D; &#x201C;I enjoy the conversations,&#x201D; and &#x201C;These conversations flow smoothly&#x201D;&#x2014;were directly adopted. All items were rated on a 6-point Likert scale ranging from &#x201C;1=extremely disagree&#x201D; to &#x201C;6=extremely agree.&#x201D; Communication competence was evaluated using 6 selected items from the Interpersonal Communication Competence Scale (ICCS) [<xref ref-type="bibr" rid="ref36">36</xref>], reflecting perspective-taking, emotional awareness, conversational flow, topic management, and sensitivity to nonverbal cues: (1) I can put myself in others&#x2019; shoes, (2) I do not know exactly what others are feeling, (3) other people think that I understand them, (4) my conversations are characterized by smooth shifts from one topic to the next, (5) I take charge of conversations I am in by negotiating what topics we talk about, and (6) in conversations, I perceive not only what others say but also what they do not say. Responses were rated on a 4-point Likert scale ranging from &#x201C;1=extremely disagree&#x201D; to &#x201C;4=extremely agree.&#x201D;</p></sec><sec id="s2-4"><title>Secondary Outcome Measures</title><sec id="s2-4-1"><title>Health-Related Capacity</title><p>Health-related capacity was evaluated using measures of health literacy and enablement. Health literacy was assessed with three items from the European Health Literacy Survey Questionnaire (HLS-EU-Q47) [<xref ref-type="bibr" rid="ref37">37</xref>], including (1) finding information on treatments of illness that concern you, (2) finding information on how to manage mental health problems such as stress or depression, and (3) judging which everyday behavior (such as drinking and eating habits and exercise) is related to your health. Responses were rated on a 4-point Likert-scale ranging from &#x201C;1=very difficult&#x201D; to &#x201C;4=very easy.&#x201D; A Chinese version of the HLS-EU-Q47 was previously validated to assess health literacy in Chinese populations [<xref ref-type="bibr" rid="ref38">38</xref>]. Self-care competence was examined by adapting 6 items from the Patient Enablement Instrument (PEI) to the intervention context: (1) able to cope with life, (2) able to understand your health condition, (3) able to cope with your health condition, (4) able to keep yourself healthy, (5) confident about your health, and (6) able to help yourself. Responses were rated on a 3-point Likert scale: &#x201C;much better,&#x201D; &#x201C;better,&#x201D; and &#x201C;same or less.&#x201D; The original PEI was previously translated and validated in the Chinese population [<xref ref-type="bibr" rid="ref39">39</xref>].</p></sec><sec id="s2-4-2"><title>Game Experience</title><p>Game experience was evaluated after the intervention using the following five questions about the board game: (1) fun to play, (2) encourage intergenerational communication, (3) enhancement of health knowledge, (4) satisfaction with the mission card design, and (5) overall satisfaction with the experience. Responses were rated on a 4-point Likert scale ranging from &#x201C;extremely disagree&#x201D; to &#x201C;extremely agree.&#x201D; Participants were also asked about their perceived game engagement on a 10-point scale ranging from very disengaged (0) to very engaged (10).</p><p>Demographic data were collected before the intervention, including age, gender, living arrangement, education attained, marital status, religion, and self-reported noncommunicable diseases.</p><p>All participants were invited to focus group discussions immediately after the game intervention and post survey to collect immediate narrative feedback. The focus groups, consisting primarily of participants from the same age group, were conducted to explore the dialogue experience and views on the board game design. For participants who could not join the focus groups but wished to elaborate on their opinions of the board game, in-depth individual interviews were scheduled within 10 days of their board game experience to minimize recall bias. The focus group discussions and individual interviews lasted approximately 45&#x2010;60 minutes, were audiotaped, and participants were invited to freely express relevant ideas on the discussion topics. The qualitative interviews were led by researchers experienced in qualitative data collection using a discussion guide to discuss [<xref ref-type="bibr" rid="ref40">40</xref>] with three major components, including (1) attitudes toward intergenerational communication, (2) healthy aging, and (3) views on the design and application of the card game.</p></sec></sec><sec id="s2-5"><title>Data Analysis</title><p>A quantitative analysis of the survey responses was conducted using IBM SPSS (version 29.0). Sample characteristics were reported as descriptive statistics. Items related to intergenerational communication satisfaction, communication competence, health literacy, and the patient enablement index were summed to yield total scores, whereas paired <italic>t</italic> tests were performed to detect significant changes in target outcomes with 95% CIs. Subgroup analyses by age group were further conducted to examine the impact of the card game across different generations. Cohen <italic>d</italic> of the three target outcomes (intergenerational communication satisfaction, communication competence, and health literacy) was computed using the mean difference before and after the intervention to evaluate the effect sizes, and Hedges correction was applied for subgroups with n&#x003C;20 [<xref ref-type="bibr" rid="ref41">41</xref>]. Effect sizes were considered small, medium, and large with cutoffs of 0.2, 0.5, and 0.8, respectively [<xref ref-type="bibr" rid="ref41">41</xref>,<xref ref-type="bibr" rid="ref42">42</xref>]. Findings related to key game experience components, including &#x201C;fun to play,&#x201D; &#x201C;encourage intergenerational communication,&#x201D; &#x201C;enhance health knowledge,&#x201D; and &#x201C;satisfied with board game question and mission design,&#x201D; were first presented descriptively. To further examine the associations between the key game experience components and the likelihood of reporting higher levels of overall satisfaction and game engagement, multivariate binary logistic regression models were conducted. For these analyses, the original Likert-scale or continuous scale outcome variables were dichotomized into &#x201C;higher&#x201D; vs &#x201C;lower&#x201D; satisfaction or engagement. A higher level of satisfaction was defined as a response of &#x201C;strongly agree&#x201D; on the 4-point Likert satisfaction scale, while a higher level of engagement was defined as a score of 9&#x2010;10 on the 0&#x2010;10 engagement scale. The reported odds ratios (ORs) and corresponding 95% CIs were adjusted for age group in the models. A <italic>P</italic> value of &#x003C;.05 was considered statistically significant.</p><p>Audiotapes recorded during the qualitative sessions were transcribed verbatim, and the transcripts were managed with Microsoft Excel. Experiences related to the game in three aspects, including intergenerational communication, health-related capacity, and overall playing experience, were identified by thematic analysis. The themes and quotes were identified with reference to the discussion guide, and the transcripts were coded twice by 2 independent reviewers to develop the study codebook. With the emergent and recurrent themes identified from the transcripts, these codes were checked and discussed among the independent reviewers to enhance consistency throughout the analysis. Codes were discussed among the research team in case of disagreements. Excerpts were quoted to illustrate the findings uncovered from the qualitative phase.</p></sec><sec id="s2-6"><title>Ethical Considerations</title><p>The tabletop game intervention is a component of a social isolation project approved by the Chinese University of Hong Kong Survey and Behavioral Research Ethics Committee (SBRE-21&#x2010;0870). Before the game intervention, informed consent was obtained from participants for participation in the game, surveys, qualitative interviews, and audiotaping.</p></sec></sec><sec id="s3" sec-type="results"><title>Results</title><sec id="s3-1"><title>Demographics</title><p>A total of 81 participants were enrolled in the tabletop game, and 68 completed the intervention and evaluations, yielding a response rate of 84%. A total of 19 game groups were arranged, each involving 3&#x2010;5 participants with at least 1 participant from each of 3 age groups. Participants were distributed across the 3 age groups (<xref ref-type="table" rid="table1">Table 1</xref>). The majority of participants were female (82.4%), living with others (61.8%), had a tertiary education level or above (55.4%), were single (47.1%), and had no religious belief (52.9%). About half of the participants reported having a communicable disease (48.5%). After the intervention and post survey, 52 of 68 (76.5%) participants were interviewed in 8 focus groups and 3 individual interviews. Only 1 focus group was mixed-aged, and 3 individual interviews were arranged due to the unavailability to join the focus group. There was no difference in the direction or richness of sharing; therefore, all focus groups and individual interviews were combined for data analysis. Regarding the characteristics of the interviewees across the 3 age groups, a higher proportion with tertiary education, who were single, who had no religious belief, and who had no chronic disease was observed among the youth, while a higher proportion living alone and being widowed or divorced was observed in the middle-aged and older adult groups. The majority of participants were female (80.8%) across all 3 age groups.</p><table-wrap id="t1" position="float"><label>Table 1.</label><caption><p>Demographic characteristics of respondents.</p></caption><table id="table1" frame="hsides" rules="groups"><thead><tr><td align="left" valign="bottom">Demographic</td><td align="left" valign="bottom">Total<break/>(n=68),<break/>n (%)</td><td align="left" valign="bottom">Young<break/>(n=23), n (%)</td><td align="left" valign="bottom">Middle-aged (n=14), n (%)</td><td align="left" valign="bottom">Older adults (n=31), n<break/>(%)</td></tr></thead><tbody><tr><td align="left" valign="top">Age range (years)</td><td align="left" valign="top">19&#x2010;92</td><td align="left" valign="top">19&#x2010;33</td><td align="left" valign="top">46&#x2010;64</td><td align="left" valign="top">66&#x2010;92</td></tr><tr><td align="left" valign="top" colspan="5">Sex</td></tr><tr><td align="left" valign="top">&#x2003;Male</td><td align="left" valign="top">12 (17.6)</td><td align="left" valign="top">7 (30.4)</td><td align="left" valign="top">1 (7.1)</td><td align="left" valign="top">4 (12.9)</td></tr><tr><td align="left" valign="top">&#x2003;Female</td><td align="left" valign="top">56 (82.4)</td><td align="left" valign="top">16 (69.6)</td><td align="left" valign="top">13 (92.9)</td><td align="left" valign="top">27 (87.1)</td></tr><tr><td align="left" valign="top" colspan="5">Live status</td></tr><tr><td align="left" valign="top">&#x2003;Living alone</td><td align="left" valign="top">26 (38.2)</td><td align="left" valign="top">1 (4.4)</td><td align="left" valign="top">4 (28.6)</td><td align="left" valign="top">21 (67.7)</td></tr><tr><td align="left" valign="top">&#x2003;Living with others</td><td align="left" valign="top">42 (61.8)</td><td align="left" valign="top">22 (95.6)</td><td align="left" valign="top">10 (71.4)</td><td align="left" valign="top">10 (32.3)</td></tr><tr><td align="left" valign="top" colspan="5">Education level</td></tr><tr><td align="left" valign="top">&#x2003;Primary or below</td><td align="left" valign="top">7 (10.3)</td><td align="left" valign="top">0 (0.0)</td><td align="left" valign="top">0 (0.0)</td><td align="left" valign="top">7 (23.3)</td></tr><tr><td align="left" valign="top">&#x2003;Secondary</td><td align="left" valign="top">23 (33.8)</td><td align="left" valign="top">1 (4.3)</td><td align="left" valign="top">5 (35.7)</td><td align="left" valign="top">17 (56.7)</td></tr><tr><td align="left" valign="top">&#x2003;Tertiary or above</td><td align="left" valign="top">37 (54.4)</td><td align="left" valign="top">22 (95.7)</td><td align="left" valign="top">9 (64.3)</td><td align="left" valign="top">6 (20.0)</td></tr><tr><td align="left" valign="top" colspan="5">Relationship status</td></tr><tr><td align="left" valign="top">&#x2003;Single</td><td align="left" valign="top">32 (47.1)</td><td align="left" valign="top">19 (82.6)</td><td align="left" valign="top">3 (21.4)</td><td align="left" valign="top">10 (32.3)</td></tr><tr><td align="left" valign="top">&#x2003;Married or stable relationship</td><td align="left" valign="top">18 (26.5)</td><td align="left" valign="top">3 (13.0)</td><td align="left" valign="top">7 (50.0)</td><td align="left" valign="top">8 (25.8)</td></tr><tr><td align="left" valign="top">&#x2003;Widowed or divorced</td><td align="left" valign="top">18 (26.5)</td><td align="left" valign="top">1 (4.3)</td><td align="left" valign="top">4 (28.6)</td><td align="left" valign="top">13 (41.9)</td></tr><tr><td align="left" valign="top" colspan="5">Religion</td></tr><tr><td align="left" valign="top">&#x2003;No</td><td align="left" valign="top">36 (52.9)</td><td align="left" valign="top">17 (73.9)</td><td align="left" valign="top">3 (21.4)</td><td align="left" valign="top">16 (51.6)</td></tr><tr><td align="left" valign="top">&#x2003;Yes or traditional worship</td><td align="left" valign="top">32 (47.1)</td><td align="left" valign="top">6 (26.1)</td><td align="left" valign="top">11 (78.6)</td><td align="left" valign="top">15 (48.4)</td></tr><tr><td align="left" valign="top" colspan="5">Self-reported noncommunicable disease</td></tr><tr><td align="left" valign="top">&#x2003;No</td><td align="left" valign="top">35 (51.5)</td><td align="left" valign="top">21 (91.3)</td><td align="left" valign="top">8 (57.1)</td><td align="left" valign="top">6 (19.4)</td></tr><tr><td align="left" valign="top">&#x2003;Yes</td><td align="left" valign="top">33 (48.5)</td><td align="left" valign="top">2 (8.7)</td><td align="left" valign="top">6 (42.9)</td><td align="left" valign="top">25 (81.6)</td></tr></tbody></table></table-wrap></sec><sec id="s3-2"><title>Intergenerational Communication</title><p>There was a significant improvement in the participants&#x2019; self-ratings of communication satisfaction, with a mean difference of &#x2212;2.76 (95% CI &#x2212;3.66 to &#x2212;1.87; <xref ref-type="table" rid="table2">Table 2</xref>). Participants across all 3 age groups showed significant improvement after the intervention, with mean differences of &#x2212;2.52 in young adults, &#x2212;3.93 in middle-aged adults, and &#x2212;2.42 in older adults. The largest effect size was observed in the middle-aged group (Cohen <italic>d</italic>=1.13). For participants&#x2019; ratings of communication competence, significant improvement was also observed after the intervention, with a mean difference of &#x2212;1.04 (95% CI &#x2212;1.71 to &#x2212;0.37). Improvement was shown across all 3 age groups, but statistically significant improvement was observed only among older adults, with a mean difference of &#x2212;1.32 (95% CI &#x2212;2.52 to 0.12). Comparing the 2 communication dimensions, a larger effect size was observed for communication satisfaction (medium effect size of 0.75) than in communication competence (small effect size of 0.38) after the intervention.</p><table-wrap id="t2" position="float"><label>Table 2.</label><caption><p>Effectiveness of the intervention on intergenerational communication.</p></caption><table id="table2" frame="hsides" rules="groups"><thead><tr><td align="left" valign="bottom">Intergenerational communication and measurement</td><td align="left" valign="bottom">Total (N=68)</td><td align="left" valign="bottom">Young (n=23)</td><td align="left" valign="bottom">Middle-aged (n=14)</td><td align="left" valign="bottom">Older adults (n=31)</td></tr></thead><tbody><tr><td align="left" valign="top" colspan="5">Communication</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Baseline, mean (SD)</td><td align="left" valign="top">18.57 (3.31)</td><td align="left" valign="top">18.48 (2.57)</td><td align="left" valign="top">18.14 (3.53)</td><td align="left" valign="top">18.84 (3.74)</td></tr><tr><td align="left" valign="top" colspan="5">Satisfaction</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Intervention, mean (SD)</td><td align="left" valign="top">21.34 (1.87)</td><td align="left" valign="top">21.00 (2.20)</td><td align="left" valign="top">22.07 (1.73)</td><td align="left" valign="top">21.26 (1.61)</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Baseline intervention, mean (95% CI)<sup><xref ref-type="table-fn" rid="table2fn1">a</xref></sup></td><td align="left" valign="top">&#x2212;2.76 (&#x2212;3.66 to &#x2212;1.87)<sup><xref ref-type="table-fn" rid="table2fn2">b</xref></sup></td><td align="left" valign="top">&#x2212;2.52 (&#x2212;4.02; &#x2212;1.02)<sup><xref ref-type="table-fn" rid="table2fn2">b</xref></sup></td><td align="left" valign="top">&#x2212;3.93 (&#x2212;5.82; &#x2212;2.04)<sup><xref ref-type="table-fn" rid="table2fn2">b</xref></sup></td><td align="left" valign="top">&#x2212;2.42 (&#x2212;3.91; &#x2212;0.93)<sup><xref ref-type="table-fn" rid="table2fn2">b</xref></sup></td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Cohen <italic>d<sup><xref ref-type="table-fn" rid="table2fn1">a</xref></sup></italic></td><td align="left" valign="top">0.745</td><td align="left" valign="top">0.728</td><td align="left" valign="top">1.131</td><td align="left" valign="top">0.595</td></tr><tr><td align="left" valign="top" colspan="5">Communication</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Baseline, mean (SD)</td><td align="left" valign="top">17.62 (2.73)</td><td align="left" valign="top">18.26 (2.40)</td><td align="left" valign="top">18.43 (2.44)</td><td align="left" valign="top">16.77 (2.91)</td></tr><tr><td align="left" valign="top" colspan="5">Competence</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Intervention, mean (SD)</td><td align="left" valign="top">18.66 (2.33)</td><td align="left" valign="top">19.34 (2.21)</td><td align="left" valign="top">18.79 (2.36)</td><td align="left" valign="top">18.10 (2.34)</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Baseline intervention, mean (95% CI)<sup><xref ref-type="table-fn" rid="table2fn1">a</xref></sup></td><td align="left" valign="top">&#x2212;1.04 (&#x2212;1.71 to &#x2212;0.37)<sup><xref ref-type="table-fn" rid="table2fn3">c</xref></sup></td><td align="left" valign="top">&#x2212;1.09 (&#x2212;2.23 to 0.06)</td><td align="left" valign="top">&#x2212;0.36 (&#x2212;1.22 to 0.51)</td><td align="left" valign="top">&#x2212;1.32 (&#x2212;2.52 to &#x2212;0.12)<sup><xref ref-type="table-fn" rid="table2fn3">c</xref></sup></td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Cohen <italic>d<sup><xref ref-type="table-fn" rid="table2fn1">a</xref></sup></italic></td><td align="left" valign="top">0.377</td><td align="left" valign="top">0.411</td><td align="left" valign="top">0.224</td><td align="left" valign="top">0.404</td></tr></tbody></table><table-wrap-foot><fn id="table2fn1"><p><sup>a</sup>Cohen <italic>d</italic> was computed with the mean difference by Hedges correction for n&#x003C;20.</p></fn><fn id="table2fn2"><p><sup>b</sup>Paired <italic>t</italic> test.</p></fn><fn id="table2fn3"><p><sup>c</sup><italic>P</italic>&#x003C;.05</p></fn></table-wrap-foot></table-wrap><p>Qualitative interviews supported these quantitative findings, showing that the intervention facilitated easier and more relaxed communication.</p><p>A young participant remarked:</p><disp-quote><p>Sometimes, when talking to middle-aged and older individuals, you may not always know what to say. Not everyone is skilled in discussing various topics with others. On the contrary, this approach raises topics for conversation on which everyone can share their opinions. It&#x2019;s not too tense, and it makes the conversation with them much easier.</p><attrib>BG22 (E)</attrib></disp-quote><p>A middle-aged participant further added:</p><disp-quote><p>&#x2026; as players often raise different answers, the contrast between them may stimulate even the shy ones to stay engaged with the tasks and responses. This promotes communication, or even builds the trust for any physical assistance with the action tasks when necessary.</p><attrib>CUBG35 (B)</attrib></disp-quote><p>An older adult participant also shared:</p><disp-quote><p>The gamification provides a welcoming space to share personal matters (anonymously), which helps players to soothe and relax, especially on sensitive topics that might be difficult to bring up with friends, as you may be uncertain if the friend may spread the word unintentionally.</p><attrib>BG26</attrib></disp-quote></sec><sec id="s3-3"><title>Health-Related Capacity</title><p>Health literacy significantly improved after the intervention (<xref ref-type="table" rid="table3">Table 3</xref>). Across the 3 age groups, significant improvements in health literacy with a significant result were observed in the middle-aged (mean difference &#x2212;0.86, 95% CI &#x2212;1.60 to &#x2212;0.11) and older adult groups (mean difference &#x2212;1.19, 95% CI &#x2212;1.96 to &#x2212;0.43) but not in the youth group (mean difference &#x2212;0.13, 95% CI &#x2212;0.88 to 0.62). Focusing on the patient enablement effect of the tabletop game intervention, PEI scores significantly increased (<xref ref-type="table" rid="table3">Table 3</xref>). A comparison of results across the 3 age groups showed that older adults&#x2019; PEI (mean 6.10, SD 2.18) was significantly higher than that of the young adult group (mean 4.22, SD 2.59). However, no significant difference was observed in the other comparisons. Details of the comparisons are tabulated in <xref ref-type="table" rid="table2">Table 2</xref>.</p><table-wrap id="t3" position="float"><label>Table 3.</label><caption><p>Effectiveness of the intervention on health enhancement.</p></caption><table id="table3" frame="hsides" rules="groups"><thead><tr><td align="left" valign="bottom">Health enhancement and measurement</td><td align="left" valign="bottom">Total (n=68)</td><td align="left" valign="bottom">Young (n=23), mean (SD)</td><td align="left" valign="bottom">Middle-aged (n=14), mean (SD)</td><td align="left" valign="bottom">Older adults (n=31), mean (SD)</td></tr></thead><tbody><tr><td align="left" valign="top" colspan="5">Health literacy</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Baseline, mean (SD)</td><td align="left" valign="top">8.59 (2.29)</td><td align="left" valign="top">10.00 (1.38)</td><td align="left" valign="top">8.93 (2.06)</td><td align="left" valign="top">7.39 (2.33)</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Intervention, mean (SD)</td><td align="left" valign="top">9.35 (1.74)</td><td align="left" valign="top">10.13 (1.46)</td><td align="left" valign="top">9.79 (1.48)</td><td align="left" valign="top">8.58 (1.77)</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Baseline intervention, mean (95% CI)<sup><xref ref-type="table-fn" rid="table3fn1">a</xref></sup></td><td align="left" valign="top">&#x2212;0.76 (&#x2212;1.22 to &#x2212;0.31)<sup><xref ref-type="table-fn" rid="table3fn2">b</xref></sup></td><td align="left" valign="top">&#x2212;0.13 (&#x2212;0.88 to 0.62)</td><td align="left" valign="top">&#x2212;0.86 (&#x2212;1.60 to &#x2212;0.11)<sup><xref ref-type="table-fn" rid="table3fn2">b</xref></sup></td><td align="left" valign="top">&#x2212;1.19 (&#x2212;1.96 to &#x2212;0.43)<sup><xref ref-type="table-fn" rid="table3fn2">b</xref></sup></td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Cohen <italic>d</italic><sup><xref ref-type="table-fn" rid="table3fn3">c</xref></sup></td><td align="left" valign="top">0.409</td><td align="left" valign="top">0.075</td><td align="left" valign="top">0.624</td><td align="left" valign="top">0.572</td></tr><tr><td align="left" valign="top" colspan="5">Patient</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Intervention, mean (SD)</td><td align="left" valign="top">5.41 (2.78)</td><td align="left" valign="top">4.22 (2.59)</td><td align="left" valign="top">5.86 (3.68)</td><td align="left" valign="top">6.10 (2.18)</td></tr><tr><td align="left" valign="top" colspan="5">Enablement</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>One-way ANOVA (<italic>P</italic> value)</td><td align="left" valign="top">.04<sup><xref ref-type="table-fn" rid="table3fn2">b</xref></sup></td><td align="char" char="." valign="top">&#x2014;<sup><xref ref-type="table-fn" rid="table3fn4">d</xref></sup></td><td align="left" valign="top">&#x2014;</td><td align="left" valign="top">&#x2014;</td></tr><tr><td align="left" valign="top" colspan="5">Index (PEI<sup><xref ref-type="table-fn" rid="table3fn5">e</xref></sup>)</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Post hoc test, group comparison<sup><xref ref-type="table-fn" rid="table3fn6">f</xref></sup></td><td align="left" valign="top">1=2; 2=3; 3&#x003E;1</td><td align="left" valign="top">&#x2014;</td><td align="left" valign="top">&#x2014;</td><td align="left" valign="top">&#x2014;</td></tr></tbody></table><table-wrap-foot><fn id="table3fn1"><p><sup>a</sup>Paired <italic>t</italic> test.</p></fn><fn id="table3fn2"><p><sup>b</sup><italic>P</italic>&#x003C;.05.</p></fn><fn id="table3fn3"><p><sup>c</sup>Cohen <italic>d</italic> was computed with the mean difference by Hedges correction for n&#x003C;20.</p></fn><fn id="table3fn4"><p><sup>d</sup>Not applicable.</p></fn><fn id="table3fn5"><p><sup>e</sup>PEI: Patient Enablement Instrument.</p></fn><fn id="table3fn6"><p><sup>f</sup>For the post hoc test (Bonferroni): 1=young, 2=middle aged, and 3=older adults.</p></fn></table-wrap-foot></table-wrap><p>Qualitative data corroborated these results, and a young participant indicated the benefits of the intervention in enhancing health literacy, particularly regarding mental health:</p><disp-quote><p>There were several cards that addressed topics like how to cope when you're under a lot of stress, or what might make you feel down emotionally. When discussing these topics, everyone can reflect more on their own experiences. It makes us think about times when we ourselves may have felt a lot of emotional pressure or faced emotional issues. Some of the cards also ask how you would cope with such situations, and everyone can share their experiences. This allows for the exchange of skills and strategies for dealing with various topics.</p><attrib>BG22 (E)</attrib></disp-quote><p>A middle-aged participant highlighted:</p><disp-quote><p>The youth and I (middle-aged) had no idea of the welfare offered by the healthcare voucher or the senior citizen card; we had to check online immediately to learn the benefits&#x2026; it is like acquiring new knowledge. It is not that we don&#x2019;t care, but what we knew was limited, and only then did we realise there are things experienced by the older adults that we lack understanding.</p><attrib>BG20 (5)</attrib></disp-quote><p>An older adult participant shared the impact of health literacy:</p><disp-quote><p>&#x2026; when you live to a hundred, you would need the help from a carer (social support), and you can&#x2019;t take good care of yourself. This feels powerless, and the other player agrees, sharing the same concern (about Health-related Quality of Life in ageing). We are worried that we become incapable of self-care, and this is not the ideal way (of community ageing).</p><attrib>BG26</attrib></disp-quote><p>In terms of patient enablement, a young participant noted:</p><disp-quote><p>The discussion on the HA Go (mobile application of the Hospital Authority) is important, as it provides information for carers like me, who monitored the health conditions of my family with the HA Go&#x2026; it is still a means for us to manage health regardless of physical distance...</p><attrib>CUBG13 (M)</attrib></disp-quote><p>A middle-aged participant also mentioned:</p><disp-quote><p>The tabletop game may empower the participants to cope with their future, such as guiding them to think and plan ahead&#x2026; the positive planning should be for everyone, and everyone should foster a positive mindset.</p><attrib>BG18 (4)</attrib></disp-quote><p>An older adult participant expressed:</p><disp-quote><p>Expressing my thoughts with the game play made me feel more at ease&#x2026; and by drawing the tasks randomly, we may not dodge from the problem, but to face it directly. It feels like a therapy session, and it&#x2019;s therapeutic.</p><attrib>BG15 (1)</attrib></disp-quote></sec><sec id="s3-4"><title>Game Experience</title><p>A strong positive experience with the tabletop game was revealed, with responses heavily inclined toward &#x201C;agree&#x201D; and &#x201C;extremely agree&#x201D; in all 4 aspects of game experience. The highest proportion of participants found that the tabletop game could encourage intergenerational communication, with 51.5% strongly agreeing, followed by &#x201C;fun to play&#x201D; (44.1%), &#x201C;satisfied with mission card design&#x201D; (30.9%), and &#x201C;enhanced our health knowledge&#x201D; (26.5%). The 4 aspects of game experience are reported in <xref ref-type="table" rid="table4">Table 4</xref>. The association between game experience and engagement, and overall satisfaction is reported in <xref ref-type="table" rid="table5">Table 5</xref>. It was found that &#x201C;encourage intergenerational communication&#x201D; (OR 4.49, 95% CI 1.09 to 18.58) was significantly associated with participants&#x2019; engagement in the tabletop game, whereas &#x201C;encourage intergenerational communication&#x201D; (OR 6.22, 95% CI 1.03 to 37.37) and &#x201C;satisfied with mission card design&#x201D; (OR 10.20, 95% CI 1.46 to 71.37) were significantly associated with the overall satisfaction of the tabletop game.</p><table-wrap id="t4" position="float"><label>Table 4.</label><caption><p>Experience of the gamification-based intervention.</p></caption><table id="table4" frame="hsides" rules="groups"><thead><tr><td align="left" valign="bottom">Gamification-based intervention component</td><td align="left" valign="bottom">Higher level of satisfaction, n (%)</td><td align="left" valign="bottom">Higher level of satisfaction<sup><xref ref-type="table-fn" rid="table4fn1">a</xref></sup>, n (%)</td><td align="left" valign="bottom"><italic>P</italic> value<sup><xref ref-type="table-fn" rid="table4fn2">b</xref></sup></td><td align="left" valign="bottom">Higher level of engagement<sup><xref ref-type="table-fn" rid="table4fn3">c</xref></sup>, n (%)</td><td align="left" valign="bottom"><italic>P</italic> value<sup><xref ref-type="table-fn" rid="table4fn2">b</xref></sup></td></tr></thead><tbody><tr><td align="left" valign="top" colspan="6">Fun to play</td></tr><tr><td align="left" valign="top">&#x2003;Agree and disagree</td><td align="left" valign="top">38 (55.9)</td><td align="left" valign="top">5 (13.2)</td><td align="left" valign="top">&#x003C;.001</td><td align="left" valign="top">18 (47.4)</td><td align="left" valign="top">.001</td></tr><tr><td align="left" valign="top">&#x2003;Strongly agree</td><td align="left" valign="top">30 (44.1)</td><td align="left" valign="top">23 (46.7)</td><td align="left" valign="top">&#x003C;.001</td><td align="left" valign="top">26 (86.7)</td><td align="left" valign="top">.001</td></tr><tr><td align="left" valign="top" colspan="6">Encourage intergenerational communication</td></tr><tr><td align="left" valign="top">&#x2003;Agree and disagree</td><td align="left" valign="top">33 (48.5)</td><td align="left" valign="top">4 (12.1)</td><td align="left" valign="top">&#x003C;.001</td><td align="left" valign="top">14 (42.4)</td><td align="left" valign="top">&#x003C;.001</td></tr><tr><td align="left" valign="top">&#x2003;Strongly agree</td><td align="left" valign="top">35 (51.5)</td><td align="left" valign="top">24 (68.6)</td><td align="left" valign="top">&#x003C;.001</td><td align="left" valign="top">30 (85.7)</td><td align="left" valign="top">&#x003C;.001</td></tr><tr><td align="left" valign="top" colspan="6">Enhance health knowledge</td></tr><tr><td align="left" valign="top">&#x2003;Agree and disagree</td><td align="left" valign="top">50 (73.5)</td><td align="left" valign="top">13 (26)</td><td align="left" valign="top">&#x003C;.001</td><td align="left" valign="top">28 (56)</td><td align="left" valign="top">.020</td></tr><tr><td align="left" valign="top">&#x2003;Strongly agree</td><td align="left" valign="top">18 (26.5)</td><td align="left" valign="top">15 (83.3)</td><td align="left" valign="top">&#x003C;.001</td><td align="left" valign="top">16 (88.9)</td><td align="left" valign="top">.026</td></tr><tr><td align="left" valign="top" colspan="6">Satisfaction with board game questions and mission design</td></tr><tr><td align="left" valign="top">&#x2003;Agree and disagree</td><td align="left" valign="top">47 (69.1)</td><td align="left" valign="top">9 (19.2)</td><td align="left" valign="top">&#x003C;.001</td><td align="left" valign="top">26 (55.3)</td><td align="left" valign="top">.026</td></tr><tr><td align="left" valign="top">&#x2003;Strongly agree</td><td align="left" valign="top">21 (30.9)</td><td align="left" valign="top">19 (90.5)</td><td align="left" valign="top">&#x003C;.001</td><td align="left" valign="top">18 (64.7)</td><td align="left" valign="top">&#x003C;.05</td></tr></tbody></table><table-wrap-foot><fn id="table4fn1"><p><sup>a</sup>A higher level of satisfaction is defined as &#x201C;strongly agree&#x201D; satisfaction.</p></fn><fn id="table4fn2"><p><sup>b</sup>Chi-square and Fisher exact test were conducted.</p></fn><fn id="table4fn3"><p><sup>c</sup>A higher level of engagement is defined as scoring 9&#x2010;10 on the engagement question.</p></fn></table-wrap-foot></table-wrap><table-wrap id="t5" position="float"><label>Table 5.</label><caption><p>Relationship between gamification-based intervention components and board game experience.</p></caption><table id="table5" frame="hsides" rules="groups"><thead><tr><td align="left" valign="bottom">Board game experience</td><td align="left" valign="bottom">Higher level of satisfaction<sup><xref ref-type="table-fn" rid="table5fn1">a</xref></sup>, adjusted OR<sup><xref ref-type="table-fn" rid="table5fn2">b</xref></sup> (95% CI)</td><td align="left" valign="bottom">Higher level of game engagement<sup><xref ref-type="table-fn" rid="table5fn3">c</xref></sup>, adjusted OR<sup><xref ref-type="table-fn" rid="table5fn2">b</xref></sup> (95% CI)</td></tr></thead><tbody><tr><td align="left" valign="top">Intercept</td><td align="left" valign="top">0.07 (0.012&#x2010;0.39)<sup><xref ref-type="table-fn" rid="table5fn4">d</xref></sup></td><td align="left" valign="top">0.57 (0.19-1.75)</td></tr><tr><td align="left" valign="top" colspan="3">Fun to play</td></tr><tr><td align="left" valign="top">&#x2003;Agree and disagree</td><td align="left" valign="top">Ref<sup><xref ref-type="table-fn" rid="table5fn5">e</xref></sup></td><td align="left" valign="top">Ref</td></tr><tr><td align="left" valign="top">&#x2003;Strongly agree</td><td align="left" valign="top">4.63 (0.71&#x2010;30.02)</td><td align="left" valign="top">2.73 (0.48-15.56)</td></tr><tr><td align="left" valign="top" colspan="2">Encourage intergenerational communication</td><td align="left" valign="top"/></tr><tr><td align="left" valign="top">&#x2003;Agree and disagree</td><td align="left" valign="top">Ref</td><td align="left" valign="top">Ref</td></tr><tr><td align="left" valign="top">&#x2003;Strongly agree</td><td align="left" valign="top">6.22 (1.03&#x2010;37.37)<sup><xref ref-type="table-fn" rid="table5fn4">d</xref></sup></td><td align="left" valign="top">4.49 (1.09-18.58)<sup><xref ref-type="table-fn" rid="table5fn4">d</xref></sup></td></tr><tr><td align="left" valign="top" colspan="2">Enhance health knowledge</td><td align="left" valign="top"/></tr><tr><td align="left" valign="top">&#x2003;Agree and disagree</td><td align="left" valign="top">Ref</td><td align="left" valign="top">Ref</td></tr><tr><td align="left" valign="top">&#x2003;Strongly agree</td><td align="left" valign="top">3.67 (0.24&#x2010;56.60)</td><td align="left" valign="top">1.47 (0.18-12.11)</td></tr><tr><td align="left" valign="top" colspan="2">Satisfied with mission card design</td><td align="left" valign="top"/></tr><tr><td align="left" valign="top">&#x2003;Agree and disagree</td><td align="left" valign="top">Ref</td><td align="left" valign="top">Ref</td></tr><tr><td align="left" valign="top">&#x2003;Strongly agree</td><td align="left" valign="top">10.20 (1.46&#x2010;71.37)<sup><xref ref-type="table-fn" rid="table5fn4">d</xref></sup></td><td align="left" valign="top">1.07 (0.16-7.12)</td></tr></tbody></table><table-wrap-foot><fn id="table5fn1"><p><sup>a</sup>A higher level of satisfaction is defined as &#x201C;strongly agree&#x201D; satisfaction.  </p></fn><fn id="table5fn2"><p><sup>b</sup>Adjusted by 3 age groups: 18&#x2010;39 years, 40&#x2010;64 years, and &#x003E;65 years.</p></fn><fn id="table5fn3"><p><sup>c</sup>A higher level of engagement is defined as scoring 9&#x2010;10 on the engagement question.</p></fn><fn id="table5fn4"><p><sup>d</sup><italic>P</italic>&#x003C;.05.</p></fn><fn id="table5fn5"><p><sup>e</sup>Ref: reference group.</p></fn></table-wrap-foot></table-wrap><p>Regarding the qualitative findings, participants emphasized the opportunities this game offered for intergenerational interaction. For example, one young participant mentioned:</p><disp-quote><p>The tabletop game provides a chance, or a platform, for each generation to interact and communicate. You know how busy the locals are, not to mention having meals together, but it was rare for different generations just to sit together. The card game would offer motivation for different generations to come together.</p><attrib>BG27</attrib></disp-quote><p>An older adult participant further added:</p><disp-quote><p>The card game encourages activities between the youth, middle-aged, and older adults. With these opportunities, we may interact and get to know each other in a friendly setting. It is nice that we can engage with real friends.</p><attrib>CUBG30</attrib></disp-quote><p>In addition, a young participant expressed enjoyment of the game:</p><disp-quote><p>I find the game enjoyable. The tasks are simple and easy to complete. As other students shared, there are tasks that are relatively exciting and playful, especially those with a time limit or an action-based format. These game play strategies are challenging yet fun...</p><attrib>BG25 (C)</attrib></disp-quote><p>A middle-aged participant also commented on the game&#x2019;s enjoyable nature:</p><disp-quote><p>&#x2026; the older adults seem to enjoy the action tasks, and it&#x2019;s such a pleasant scene when everyone engages with the same actions on an intergenerational level.</p><attrib>CUBG34 (H)</attrib></disp-quote><p>An older adult participant reflected on the intergenerational engagement:</p><disp-quote><p>I think the card game experience is nice, and it&#x2019;s my first attendance at such a game. The intergenerational engagement seems to be drawing everyone closer, and I feel involved as it includes topics related to my childhood.</p><attrib>CUBG29</attrib></disp-quote><p>The game&#x2019;s design was recognized as a key factor in its success. A young participant mentioned:</p><disp-quote><p>I would say, first of all, what impressed me the most was that the rules of the game were very simple&#x2026; I think the key is to make sure they understand the rules of the game so they are willing to engage. If the rules were too complicated, they would likely spend too much time figuring out what to do and what each element meant. So, I believe ensuring a smooth game operation is crucial for the success of the game experience.</p><attrib>BG24 (D)</attrib></disp-quote><p>A middle-aged participant also expressed satisfaction with the game design:</p><disp-quote><p>It&#x2019;s obvious that the card game encourages expansion of social network by providing common topics and activities&#x2026; By involving adjacent players, this is a great design as there will be no dominating players, but they will share the experience together.</p><attrib>BG20</attrib></disp-quote><p>An older adult participant also acknowledged the game design:</p><disp-quote><p>Introducing oneself through playing cards makes it more interesting for everyone listening. By using this relaxed atmosphere, it allows everyone to get to know each other better.</p><attrib>CUBG25</attrib></disp-quote></sec></sec><sec id="s4" sec-type="discussion"><title>Discussion</title><sec id="s4-1"><title>Principal Findings</title><p>This intergenerational intervention yielded notable benefits in intergenerational communication, health literacy, and patient empowerment, especially for older adults. While the majority of gamification interventions for older adults have focused on evaluating the impact on health outcomes [<xref ref-type="bibr" rid="ref43">43</xref>], the current evaluation provides a comprehensive review of communication and health-related outcomes. In addition, this study highlighted the importance of leveraging gamification to enhance intergenerational communication and ultimately combat social isolation among older adults.</p><p>Across all age groups, participants reported significantly higher communication satisfaction post intervention, indicating that the game fostered enjoyable and fulfilling dialogue. While short-term increases in communication satisfaction following an engaging activity are, to some extent, expected and may partly reflect novelty or positive study participation effects, communication satisfaction reflects perceived interaction quality rather than transient mood alone. In this intervention, satisfaction was fostered through structured dialogue, guided turn-taking, and role rotation, which targeted communication processes that can plausibly generalize beyond the immediate gameplay context. Nevertheless, sustained effects cannot be inferred from the present design and require confirmation through longitudinal follow-up. Notably, only older adults showed a significant improvement in their communication competence scores, whereas younger and middle-aged adults did not. One explanation lies in baseline differences: older participants may have had fewer opportunities for rich social interaction before the study due to the prevalence of social isolation among Hong Kong&#x2019;s older population. Indeed, as of 2021, nearly 190,000 adults aged 65 years and older were living alone in Hong Kong, reflecting a 60% increase since 2011 [<xref ref-type="bibr" rid="ref44">44</xref>]. Such isolation is linked to declines in communication skills and cognitive function [<xref ref-type="bibr" rid="ref45">45</xref>]. By facilitating regular, meaningful conversations, the game likely helped older participants practice and regain communication competencies. This aligns with evidence that increasing social interaction can improve older adults&#x2019; performance on verbal communication tasks [<xref ref-type="bibr" rid="ref46">46</xref>]. In contrast, younger adults&#x2014;who typically have more daily social communication&#x2014;may have been closer to a ceiling in communication ability, limiting observable gains.</p><p>Differential effects on health literacy were also observed. Middle-aged and older participants showed significant improvements in health literacy after gameplay, whereas the youth group did not. Younger adults likely entered the study with higher baseline health literacy, given their greater exposure to education and digital information, and thus had less room for measurable improvement. Older adults, on the other hand, often start with lower health literacy and greater health knowledge gaps. The game&#x2019;s health literacy module provided an engaging, accessible means of learning health information, resulting in tangible knowledge gains for these groups. This finding is consistent with prior research showing that game-based interventions can substantially increase health-related knowledge [<xref ref-type="bibr" rid="ref47">47</xref>]. Moreover, intergenerational learning theory suggests that structured dialogue between generations creates opportunities for mutual education and attitude change [<xref ref-type="bibr" rid="ref48">48</xref>]. During the health literacy tasks, younger players might have shared digital health information or taught health concepts, benefiting their older counterparts. Reciprocally, older adults may have shared personal health experiences, which could enrich understanding for young and middle-aged adults. The middle-aged group, interestingly, also improved in health literacy, suggesting that those in midlife, often caring for both children and older adult parents, found the health knowledge and cross-generational communication practice directly relevant and empowering for their caregiving and self-care roles.</p><p>Importantly, the older group showed a significantly higher PEI score post intervention than the youth group, with no significant differences between the other groups. The high PEI score in older adults suggests that the game may have enhanced their confidence and sense of &#x201C;enablement&#x201D; in dealing with health issues. Several mechanisms could explain this. First, older participants likely felt a sense of accomplishment and agency by contributing actively to group tasks, such as sharing life experiences or completing challenges. Being listened to by younger peers may have bolstered their self-esteem and sense of purpose, which, according to Socioemotional Selectivity Theory, is highly valued in late life [<xref ref-type="bibr" rid="ref49">49</xref>]. The theory posits that as people age and perceive a shorter future time horizon, they prioritize meaningful social interactions and emotional fulfillment. Importantly, this does not imply that brief interactions with unfamiliar partners function as strong-tie relationships; rather, the intervention may have uncovered interaction contexts characterized by emotional affirmation, mutual respect, and psychological safety, which align with the socioemotional qualities prioritized in later life. In our study, the older adults&#x2019; disproportionate gains in communication ability and health literacy could be a good start toward confidence-building in intergenerational interaction and a strong sense of enablement. Moreover, the opportunity to impart wisdom and bond with younger people likely fulfilled older adults&#x2019; socioemotional goals, thereby maximizing their engagement and leading to greater gains from the program. In contrast, younger participants generally have a more future-oriented outlook and myriad social connections; while they enjoyed the game, as evidenced by improved satisfaction, they may not have experienced the same degree of program gains or personal empowerment.</p><p>The outcome was a unanimous perception across all age groups that the game strengthened intergenerational communication and was well-designed, fun, and educational. These positive subjective evaluations are noteworthy given the challenge of designing content appealing to diverse ages. By using gamification&#x2014;points, challenges, and playful interactions&#x2014;the intervention kept participants intrinsically motivated. Gamification theory holds that introducing game elements into nongame contexts (such as health education) can enhance user engagement and motivation [<xref ref-type="bibr" rid="ref50">50</xref>]. Consistently, our findings show high engagement and satisfaction scores, indicating that the game format was indeed engaging. Prior studies in older adults have also found that appropriately designed card games can acutely boost mood and well-being during play [<xref ref-type="bibr" rid="ref51">51</xref>]. Our intergenerational game seems to have capitalized on these effects, creating an enjoyable learning environment that felt less like a health workshop and more like a social gathering.</p><p>The association analyses provide further insight into what drove the intervention&#x2019;s success. We found that participants who felt the game &#x201C;encouraged intergenerational communication&#x201D; were significantly more likely to report higher engagement in the activities and greater overall satisfaction, reinforcing the importance of perceived interaction quality as a proximal outcome. In other words, when players perceived that the core purpose of the game, bridging generations, was being achieved, their involvement and satisfaction were maximized. This underscores the importance of making the intergenerational benefits salient&#x2014;participants who recognized the value in connecting with other ages likely invested more effort and attention, potentially creating a virtuous cycle of engagement and positive experience. We also found that satisfaction with the game design was strongly correlated with overall satisfaction. This highlights the role of user-centered design, encompassing elements such as clear rules, culturally relevant content, and balanced difficulty across modules, which likely enhanced enjoyment. From a gamification perspective, well-designed game mechanics (eg, rotating tasks, creative challenges, and immediate feedback through group discussion) can fulfill psychological needs such as autonomy, competence, and relatedness, leading to higher satisfaction [<xref ref-type="bibr" rid="ref52">52</xref>].</p></sec><sec id="s4-2"><title>Limitations</title><p>First, although the inclusion criteria were broad, participants voluntarily enrolled in the intervention, and the majority were female, which may not be representative of all eligible individuals; selection bias may therefore limit generalizability. However, the qualitative interviews provided in-depth insights that may help inform the design of a larger-scale randomized controlled trial. Second, intergenerational communication outcomes were assessed using selected items from validated instruments rather than the complete scales. While this may limit psychometric completeness, the selected items were purposefully chosen to reflect communicative processes relevant to brief, structured intergenerational interactions within a gamified setting. Accordingly, findings should be interpreted with appropriate caution. Full-length scales include items less applicable to this context, and their use may compromise relevance and participant engagement. Third, some outcomes were dichotomized for analysis due to skewed response distributions, which may have reduced variability and statistical power and potentially obscured differences in participants&#x2019; responses. Fourth, the sample size for the middle-aged group was comparatively smaller than that of the other 2 groups, although the minimum sample size requirement was met. This imbalance may have limited statistical power for 3-group comparisons. Finally, a 30-minute game duration was recommended, but this was not implemented strictly to sustain positive game dynamics. Variations in actual game time may influence comparisons across groups. However, these variations may also reflect natural engagement patterns in intergenerational communication settings.</p><p>In conclusion, the intergenerational card game intervention in Hong Kong demonstrated an effective approach to enhancing communication satisfaction, health literacy, and health enablement, particularly benefiting older adults in an aging, isolated population. By providing an enjoyable and structured platform for cross-generational dialogue, the game enabled meaningful engagement and mutual learning between age groups, fostering high levels of participant engagement. These findings underscore the potential of playful, socially embedded interventions to complement traditional health care services by addressing psychosocial determinants of health. Given its low cost, scalability, and high acceptability, this approach holds promise as a public health tool in aging societies worldwide. Future research should further examine the tool&#x2019;s psychometric properties and extend this work through randomized controlled trials or longitudinal studies to assess longer-term impacts on health behaviors, clinical outcomes, and broader dimensions of social connectedness.</p></sec></sec></body><back><ack><p>The authors are grateful to the Tung Wah Group of Hospitals for their joint efforts in cocreating the card game, recruiting older adults, and arranging the intervention&#x2019;s logistics. Tad Chun-kwan Ho was a major contributor to the card game development as a social worker, while Leopard Chi-keung Lam and Danielle Man-yu Chan provided tremendous support in the tabletop game development. Last but not least, the authors thank all participants for joining the game and sharing their valuable views. No generative artificial intelligence tool was used.</p></ack><notes><sec><title>Funding</title><p>We thank the Hong Kong Jockey Club Charities Trust for its funding support, which made this intervention possible.</p></sec><sec><title>Data Availability</title><p>The dataset used or analyzed is not publicly available due to confidentiality considerations and the ongoing project progress. A reasonable request may be made to the corresponding author for further consideration.</p></sec></notes><fn-group><fn fn-type="con"><p>Conceptualization and funding acquisition were undertaken by ELYW. Data curation was performed by CCWN, CKPW, and SSKL. Formal analysis was conducted by DYW, CCWN, and AWLC. An investigation was carried out by ELYW, CCWN, and DYW. Methodology, supervision, and validation were the responsibility of ELYW. Visualization was completed by CCWN and AWLC. The original draft of the paper was prepared by ELYW, CCWN, and DYW. Review and editing of the paper were undertaken by CKPW, SSKL, AWLC, and EKY.</p></fn><fn fn-type="conflict"><p>None declared.</p></fn></fn-group><glossary><title>Abbreviations</title><def-list><def-item><term id="abb1">HLS-EU-Q47</term><def><p>European Health Literacy Survey Questionnaire</p></def></def-item><def-item><term id="abb2">ICCS</term><def><p>Interpersonal Communication Competence Scale</p></def></def-item><def-item><term id="abb3">LOUE</term><def><p>Listening, Observing, Understanding, and Expression</p></def></def-item><def-item><term id="abb4">OR</term><def><p>odds ratio</p></def></def-item><def-item><term id="abb5">PEI</term><def><p>Patient Enablement Instrument</p></def></def-item><def-item><term id="abb6">WHO</term><def><p>World Health Organization</p></def></def-item></def-list></glossary><ref-list><title>References</title><ref id="ref1"><label>1</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Dwyer</surname><given-names>RJ</given-names> </name><name name-style="western"><surname>Zhuo</surname><given-names>AX</given-names> </name><name name-style="western"><surname>Dunn</surname><given-names>EW</given-names> </name></person-group><article-title>Why do people turn to smartphones during social interactions?</article-title><source>J Exp Soc Psychol</source><year>2023</year><month>11</month><volume>109</volume><fpage>104506</fpage><pub-id pub-id-type="doi">10.1016/j.jesp.2023.104506</pub-id></nlm-citation></ref><ref id="ref2"><label>2</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Verduyn</surname><given-names>P</given-names> </name><name name-style="western"><surname>Schulte-Strathaus</surname><given-names>JCC</given-names> </name><name name-style="western"><surname>Kross</surname><given-names>E</given-names> </name><name name-style="western"><surname>H&#x00FC;lsheger</surname><given-names>UR</given-names> </name></person-group><article-title>When do smartphones displace face-to-face interactions and what to do about it?</article-title><source>Comput Human Behav</source><year>2021</year><month>01</month><volume>114</volume><fpage>106550</fpage><pub-id pub-id-type="doi">10.1016/j.chb.2020.106550</pub-id></nlm-citation></ref><ref id="ref3"><label>3</label><nlm-citation citation-type="web"><article-title>From loneliness to social connection: charting a path to healthier societies</article-title><source>World Health Organization</source><year>2025</year><access-date>2026-07-07</access-date><comment><ext-link ext-link-type="uri" xlink:href="https://www.who.int/publications/i/item/978240112360">https://www.who.int/publications/i/item/978240112360</ext-link></comment></nlm-citation></ref><ref id="ref4"><label>4</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>House</surname><given-names>JS</given-names> </name><name name-style="western"><surname>Landis</surname><given-names>KR</given-names> </name><name name-style="western"><surname>Umberson</surname><given-names>D</given-names> </name></person-group><article-title>Social relationships and health</article-title><source>Science</source><year>1988</year><month>07</month><day>29</day><volume>241</volume><issue>4865</issue><fpage>540</fpage><lpage>545</lpage><pub-id pub-id-type="doi">10.1126/science.3399889</pub-id><pub-id pub-id-type="medline">3399889</pub-id></nlm-citation></ref><ref id="ref5"><label>5</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Holt-Lunstad</surname><given-names>J</given-names> </name><name name-style="western"><surname>Perissinotto</surname><given-names>C</given-names> </name></person-group><article-title>Social isolation and loneliness as medical issues</article-title><source>N Engl J Med</source><year>2023</year><month>01</month><day>19</day><volume>388</volume><issue>3</issue><fpage>193</fpage><lpage>195</lpage><pub-id pub-id-type="doi">10.1056/NEJMp2208029</pub-id><pub-id pub-id-type="medline">36648080</pub-id></nlm-citation></ref><ref id="ref6"><label>6</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Poscia</surname><given-names>A</given-names> </name><name name-style="western"><surname>Stojanovic</surname><given-names>J</given-names> </name><name name-style="western"><surname>La Milia</surname><given-names>DI</given-names> </name><etal/></person-group><article-title>Interventions targeting loneliness and social isolation among the older people: an update systematic review</article-title><source>Exp Gerontol</source><year>2018</year><month>02</month><volume>102</volume><fpage>133</fpage><lpage>144</lpage><pub-id pub-id-type="doi">10.1016/j.exger.2017.11.017</pub-id><pub-id pub-id-type="medline">29199121</pub-id></nlm-citation></ref><ref id="ref7"><label>7</label><nlm-citation citation-type="web"><article-title>Decade of healthy ageing: baseline report</article-title><source>World Health Organization</source><year>2020</year><access-date>2026-07-07</access-date><comment><ext-link ext-link-type="uri" xlink:href="https://www.who.int/publications/i/item/9789240017900">https://www.who.int/publications/i/item/9789240017900</ext-link></comment></nlm-citation></ref><ref id="ref8"><label>8</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Lyu</surname><given-names>C</given-names> </name><name name-style="western"><surname>Siu</surname><given-names>K</given-names> </name><name name-style="western"><surname>Xu</surname><given-names>I</given-names> </name><name name-style="western"><surname>Osman</surname><given-names>I</given-names> </name><name name-style="western"><surname>Zhong</surname><given-names>J</given-names> </name></person-group><article-title>Social isolation changes and long-term outcomes among older adults</article-title><source>JAMA Netw Open</source><year>2024</year><month>07</month><day>1</day><volume>7</volume><issue>7</issue><fpage>e2424519</fpage><pub-id pub-id-type="doi">10.1001/jamanetworkopen.2024.24519</pub-id><pub-id pub-id-type="medline">39046736</pub-id></nlm-citation></ref><ref id="ref9"><label>9</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Liang</surname><given-names>YY</given-names> </name><name name-style="western"><surname>Chen</surname><given-names>Y</given-names> </name><name name-style="western"><surname>Feng</surname><given-names>H</given-names> </name><etal/></person-group><article-title>Social isolation, loneliness and subsequent risk of major adverse cardiovascular events among individuals with type 2 diabetes mellitus</article-title><source>Gen Psychiatr</source><year>2023</year><volume>36</volume><issue>6</issue><fpage>e101153</fpage><pub-id pub-id-type="doi">10.1136/gpsych-2023-101153</pub-id><pub-id pub-id-type="medline">38170087</pub-id></nlm-citation></ref><ref id="ref10"><label>10</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Wong</surname><given-names>ELY</given-names> </name><name name-style="western"><surname>Qiu</surname><given-names>H</given-names> </name><name name-style="western"><surname>Cheung</surname><given-names>AWL</given-names> </name><name name-style="western"><surname>Leung</surname><given-names>HHW</given-names> </name><name name-style="western"><surname>Chen</surname><given-names>FY</given-names> </name><name name-style="western"><surname>Yeoh</surname><given-names>EK</given-names> </name></person-group><article-title>Association of social isolation with health status among community-dwelling Chinese older adults living with homecare services: a cross-sectional survey in Hong Kong</article-title><source>Front Public Health</source><year>2023</year><volume>11</volume><issue>1099734</issue><fpage>1099734</fpage><pub-id pub-id-type="doi">10.3389/fpubh.2023.1099734</pub-id><pub-id pub-id-type="medline">37333567</pub-id></nlm-citation></ref><ref id="ref11"><label>11</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Lai-Yi Wong</surname><given-names>E</given-names> </name><name name-style="western"><surname>Qiu</surname><given-names>H</given-names> </name><name name-style="western"><surname>Ho</surname><given-names>KF</given-names> </name><etal/></person-group><article-title>Association of ambient temperature with social isolation among the community-dwelling Chinese older adults: a cross-sectional study in Hong Kong</article-title><source>Heliyon</source><year>2025</year><month>01</month><day>15</day><volume>11</volume><issue>1</issue><fpage>e41721</fpage><pub-id pub-id-type="doi">10.1016/j.heliyon.2025.e41721</pub-id><pub-id pub-id-type="medline">39866493</pub-id></nlm-citation></ref><ref id="ref12"><label>12</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Hao</surname><given-names>HJ</given-names> </name><name name-style="western"><surname>Du</surname><given-names>MQ</given-names> </name><name name-style="western"><surname>Yue</surname><given-names>JY</given-names> </name></person-group><article-title>Social isolation, loneliness, and subjective wellbeing among Chinese older adults during the COVID-19 pandemic</article-title><source>Front Public Health</source><year>2024</year><volume>12</volume><fpage>1425575</fpage><pub-id pub-id-type="doi">10.3389/fpubh.2024.1425575</pub-id><pub-id pub-id-type="medline">39440171</pub-id></nlm-citation></ref><ref id="ref13"><label>13</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Wong</surname><given-names>ELY</given-names> </name><name name-style="western"><surname>Li</surname><given-names>J</given-names> </name><name name-style="western"><surname>Yuen</surname><given-names>S</given-names> </name><etal/></person-group><article-title>Vulnerable populations during COVID-19 response: health-related quality of life among Chinese population and its influence due to socio-demographic factors and loneliness</article-title><source>Front Public Health</source><year>2022</year><volume>10</volume><fpage>857033</fpage><pub-id pub-id-type="doi">10.3389/fpubh.2022.857033</pub-id><pub-id pub-id-type="medline">36081475</pub-id></nlm-citation></ref><ref id="ref14"><label>14</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Phang</surname><given-names>JK</given-names> </name><name name-style="western"><surname>Kwan</surname><given-names>YH</given-names> </name><name name-style="western"><surname>Yoon</surname><given-names>S</given-names> </name><etal/></person-group><article-title>Digital intergenerational program to reduce loneliness and social isolation among older adults: realist review</article-title><source>JMIR Aging</source><year>2023</year><month>01</month><day>4</day><volume>6</volume><fpage>e39848</fpage><pub-id pub-id-type="doi">10.2196/39848</pub-id><pub-id pub-id-type="medline">36598801</pub-id></nlm-citation></ref><ref id="ref15"><label>15</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Holloway</surname><given-names>J</given-names> </name><name name-style="western"><surname>James</surname><given-names>DL</given-names> </name><name name-style="western"><surname>Robillard</surname><given-names>A</given-names> </name><name name-style="western"><surname>Hermer</surname><given-names>J</given-names> </name><name name-style="western"><surname>Hawley</surname><given-names>N</given-names> </name><name name-style="western"><surname>Sayeed</surname><given-names>O</given-names> </name></person-group><article-title>Needs of social isolation, loneliness, and intergenerational interventions in the United States: a scoping review</article-title><source>Front Public Health</source><year>2024</year><volume>12</volume><fpage>1386651</fpage><pub-id pub-id-type="doi">10.3389/fpubh.2024.1386651</pub-id><pub-id pub-id-type="medline">39185115</pub-id></nlm-citation></ref><ref id="ref16"><label>16</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Welch</surname><given-names>V</given-names> </name><name name-style="western"><surname>Ghogomu</surname><given-names>ET</given-names> </name><name name-style="western"><surname>Barbeau</surname><given-names>VI</given-names> </name><etal/></person-group><article-title>Digital interventions to reduce social isolation and loneliness in older adults: an evidence and gap map</article-title><source>Campbell Syst Rev</source><year>2023</year><month>12</month><volume>19</volume><issue>4</issue><fpage>e1369</fpage><pub-id pub-id-type="doi">10.1002/cl2.1369</pub-id><pub-id pub-id-type="medline">38024780</pub-id></nlm-citation></ref><ref id="ref17"><label>17</label><nlm-citation citation-type="book"><person-group person-group-type="author"><name name-style="western"><surname>Lin</surname><given-names>MC</given-names> </name></person-group><person-group person-group-type="editor"><name name-style="western"><surname>Allen</surname><given-names>M</given-names> </name></person-group><article-title>Intergenerational communication</article-title><source>The SAGE Encyclopedia of Communication Research Methods</source><year>2017</year><publisher-name>SAGE Publications, Inc</publisher-name><fpage>762</fpage><lpage>766</lpage><pub-id pub-id-type="doi">10.4135/9781483381411.n264</pub-id></nlm-citation></ref><ref id="ref18"><label>18</label><nlm-citation citation-type="book"><person-group person-group-type="author"><name name-style="western"><surname>Addimando</surname><given-names>F</given-names> </name></person-group><article-title>Effective communication strategies</article-title><source>Trade Show Psychology</source><year>2024</year><publisher-name>Springer Nature Switzerland</publisher-name><fpage>53</fpage><lpage>72</lpage><pub-id pub-id-type="doi">10.1007/978-3-031-53606-9_4</pub-id></nlm-citation></ref><ref id="ref19"><label>19</label><nlm-citation citation-type="book"><person-group person-group-type="author"><name name-style="western"><surname>Arnold</surname><given-names>E</given-names> </name><name name-style="western"><surname>Boggs</surname><given-names>KU</given-names> </name></person-group><source>Interpersonal Relationships: Professional Communication Skills for Nurses</source><year>2020</year><publisher-name>Elsevier</publisher-name><pub-id pub-id-type="other">9780323544801</pub-id></nlm-citation></ref><ref id="ref20"><label>20</label><nlm-citation citation-type="book"><person-group person-group-type="author"><name name-style="western"><surname>Giles</surname><given-names>H</given-names> </name><name name-style="western"><surname>Gasiorek</surname><given-names>J</given-names> </name></person-group><person-group person-group-type="editor"><name name-style="western"><surname>Schaie</surname><given-names>KW</given-names> </name><name name-style="western"><surname>Willis</surname><given-names>SL</given-names> </name></person-group><article-title>Intergenerational communication practices</article-title><source>Handbook of the Psychology of Aging</source><year>2011</year><edition>7</edition><publisher-name>Elsevier Academic Press</publisher-name><fpage>233</fpage><lpage>247</lpage><pub-id pub-id-type="doi">10.1016/B978-0-12-380882-0.00015-2</pub-id></nlm-citation></ref><ref id="ref21"><label>21</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>S&#x00F6;llner</surname><given-names>M</given-names> </name><name name-style="western"><surname>D&#x00FC;rnberger</surname><given-names>M</given-names> </name><name name-style="western"><surname>Keller</surname><given-names>J</given-names> </name><name name-style="western"><surname>Florack</surname><given-names>A</given-names> </name></person-group><article-title>The impact of age stereotypes on well-being: strategies of selection, optimization, and compensation as mediator and regulatory focus as moderator: findings from a cross-sectional and a longitudinal study</article-title><source>J Happiness Stud</source><year>2022</year><month>02</month><volume>23</volume><issue>2</issue><fpage>635</fpage><lpage>665</lpage><pub-id pub-id-type="doi">10.1007/s10902-021-00417-x</pub-id></nlm-citation></ref><ref id="ref22"><label>22</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Landers</surname><given-names>RN</given-names> </name><name name-style="western"><surname>Bauer</surname><given-names>KN</given-names> </name><name name-style="western"><surname>Callan</surname><given-names>RC</given-names> </name></person-group><article-title>Gamification of task performance with leaderboards: a goal setting experiment</article-title><source>Comput Human Behav</source><year>2017</year><month>06</month><volume>71</volume><fpage>508</fpage><lpage>515</lpage><pub-id pub-id-type="doi">10.1016/j.chb.2015.08.008</pub-id></nlm-citation></ref><ref id="ref23"><label>23</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Skivington</surname><given-names>K</given-names> </name><name name-style="western"><surname>Matthews</surname><given-names>L</given-names> </name><name name-style="western"><surname>Simpson</surname><given-names>SA</given-names> </name><etal/></person-group><article-title>A new framework for developing and evaluating complex interventions: update of Medical Research Council guidance</article-title><source>BMJ</source><year>2021</year><month>09</month><day>30</day><fpage>n2061</fpage><pub-id pub-id-type="doi">10.1136/bmj.n2061</pub-id></nlm-citation></ref><ref id="ref24"><label>24</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Tustonja</surname><given-names>M</given-names> </name><name name-style="western"><surname>Topi&#x0107; Stipi&#x0107;</surname><given-names>D</given-names> </name><name name-style="western"><surname>Skoko</surname><given-names>I</given-names> </name><name name-style="western"><surname>&#x010C;uljak</surname><given-names>A</given-names> </name><name name-style="western"><surname>Vegar</surname><given-names>A</given-names> </name></person-group><article-title>Active listening &#x2013; a model of empathetic communication in the helping professions</article-title><source>Med Acad Integr</source><year>2024</year><month>03</month><volume>1</volume><issue>1</issue><fpage>42</fpage><lpage>47</lpage><pub-id pub-id-type="doi">10.47960/3029-3316.2024.1.1.42</pub-id></nlm-citation></ref><ref id="ref25"><label>25</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Abargil</surname><given-names>M</given-names> </name><name name-style="western"><surname>Schenkolewski</surname><given-names>A</given-names> </name><name name-style="western"><surname>Tishby</surname><given-names>O</given-names> </name></person-group><article-title>Therapists&#x2019; emotional responses and their relation to patients&#x2019; experience of attunement and responsiveness</article-title><source>Psychother Res</source><year>2025</year><month>01</month><volume>35</volume><issue>1</issue><fpage>54</fpage><lpage>66</lpage><pub-id pub-id-type="doi">10.1080/10503307.2024.2403422</pub-id><pub-id pub-id-type="medline">39508263</pub-id></nlm-citation></ref><ref id="ref26"><label>26</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Reniers</surname><given-names>R</given-names> </name><name name-style="western"><surname>Abu-Akel</surname><given-names>A</given-names> </name><name name-style="western"><surname>Seara-Cardoso</surname><given-names>A</given-names> </name></person-group><article-title>Editorial: cognitive empathy and perspective taking: understanding the mechanisms of normal and abnormal experiences and abilities</article-title><source>Front Psychiatry</source><year>2022</year><volume>13</volume><fpage>945258</fpage><pub-id pub-id-type="doi">10.3389/fpsyt.2022.945258</pub-id><pub-id pub-id-type="medline">35722573</pub-id></nlm-citation></ref><ref id="ref27"><label>27</label><nlm-citation citation-type="book"><person-group person-group-type="author"><name name-style="western"><surname>McCann</surname><given-names>RM</given-names> </name><name name-style="western"><surname>Giles</surname><given-names>H</given-names> </name><name name-style="western"><surname>Ota</surname><given-names>H</given-names> </name></person-group><person-group person-group-type="editor"><name name-style="western"><surname>Chen</surname><given-names>L</given-names> </name></person-group><article-title>Aging and communication across cultures</article-title><source>Intercultural Communication</source><year>2017</year><access-date>2026-07-07</access-date><publisher-name>De Gruyter Mouton</publisher-name><fpage>289</fpage><lpage>307</lpage><comment><ext-link ext-link-type="uri" xlink:href="https://www.researchgate.net/publication/316067070_13_Aging_and_communication_across_cultures">https://www.researchgate.net/publication/316067070_13_Aging_and_communication_across_cultures</ext-link></comment></nlm-citation></ref><ref id="ref28"><label>28</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Giles</surname><given-names>H</given-names> </name><name name-style="western"><surname>Dorjee</surname><given-names>T</given-names> </name></person-group><article-title>Communicative climates and prospects in cross-cultural gerontology</article-title><source>J Cross Cult Gerontol</source><year>2004</year><month>12</month><volume>19</volume><issue>4</issue><fpage>261</fpage><lpage>274</lpage><pub-id pub-id-type="doi">10.1023/B:JCCG.0000044684.82186.e3</pub-id><pub-id pub-id-type="medline">15604644</pub-id></nlm-citation></ref><ref id="ref29"><label>29</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Shortt</surname><given-names>M</given-names> </name><name name-style="western"><surname>Tilak</surname><given-names>S</given-names> </name><name name-style="western"><surname>Kuznetcova</surname><given-names>I</given-names> </name><name name-style="western"><surname>Martens</surname><given-names>B</given-names> </name><name name-style="western"><surname>Akinkuolie</surname><given-names>B</given-names> </name></person-group><article-title>Gamification in mobile-assisted language learning: a systematic review of Duolingo literature from public release of 2012 to early 2020</article-title><source>Comput Assist Lang Learn</source><year>2023</year><month>03</month><day>4</day><volume>36</volume><issue>3</issue><fpage>517</fpage><lpage>554</lpage><pub-id pub-id-type="doi">10.1080/09588221.2021.1933540</pub-id></nlm-citation></ref><ref id="ref30"><label>30</label><nlm-citation citation-type="book"><person-group person-group-type="author"><name name-style="western"><surname>Malamed</surname><given-names>C</given-names> </name></person-group><source>The Gamification of Learning and Instruction: Game-Based Methods and Strategies for Training and Education</source><year>2012</year><publisher-name>Pfeiffer</publisher-name><pub-id pub-id-type="doi">10.1145/2207270.2211316</pub-id><pub-id pub-id-type="other">1118191986</pub-id></nlm-citation></ref><ref id="ref31"><label>31</label><nlm-citation citation-type="confproc"><person-group person-group-type="author"><name name-style="western"><surname>Deterding</surname><given-names>S</given-names> </name><name name-style="western"><surname>Dixon</surname><given-names>D</given-names> </name><name name-style="western"><surname>Khaled</surname><given-names>R</given-names> </name><name name-style="western"><surname>Nacke</surname><given-names>L</given-names> </name></person-group><article-title>From game design elements to gamefulness: defining &#x201C;gamification&#x201D;</article-title><conf-name>MindTrek &#x2019;11: Proceedings of the 15th International Academic MindTrek Conference: Envisioning Future Media Environments</conf-name><conf-date>Sep 28-30, 2011</conf-date><pub-id pub-id-type="doi">10.1145/2181037.2181040</pub-id></nlm-citation></ref><ref id="ref32"><label>32</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Talley</surname><given-names>MH</given-names> </name><name name-style="western"><surname>Ogle</surname><given-names>N</given-names> </name><name name-style="western"><surname>Wingo</surname><given-names>N</given-names> </name><name name-style="western"><surname>Roche</surname><given-names>C</given-names> </name><name name-style="western"><surname>Willig</surname><given-names>J</given-names> </name></person-group><article-title>Kaizen: interactive gaming for diabetes patient education</article-title><source>Games Health J</source><year>2019</year><month>12</month><volume>8</volume><issue>6</issue><fpage>423</fpage><lpage>431</lpage><pub-id pub-id-type="doi">10.1089/g4h.2018.0107</pub-id><pub-id pub-id-type="medline">31769723</pub-id></nlm-citation></ref><ref id="ref33"><label>33</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Bicen</surname><given-names>H</given-names> </name><name name-style="western"><surname>Kocakoyun</surname><given-names>S</given-names> </name></person-group><article-title>Perceptions of students for gamification approach: Kahoot as a case study</article-title><source>Int J Emerg Technol Learn</source><year>2018</year><volume>13</volume><issue>2</issue><fpage>72</fpage><pub-id pub-id-type="doi">10.3991/ijet.v13i02.7467</pub-id></nlm-citation></ref><ref id="ref34"><label>34</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Kadam</surname><given-names>P</given-names> </name><name name-style="western"><surname>Bhalerao</surname><given-names>S</given-names> </name></person-group><article-title>Sample size calculation</article-title><source>Int J Ayurveda Res</source><year>2010</year><month>01</month><volume>1</volume><issue>1</issue><fpage>55</fpage><lpage>57</lpage><pub-id pub-id-type="doi">10.4103/0974-7788.59946</pub-id><pub-id pub-id-type="medline">20532100</pub-id></nlm-citation></ref><ref id="ref35"><label>35</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Hecht</surname><given-names>ML</given-names> </name></person-group><article-title>The conceptualization and measurement of interpersonal communication satisfaction</article-title><source>Human Comm Res</source><year>1978</year><month>03</month><volume>4</volume><issue>3</issue><fpage>253</fpage><lpage>264</lpage><pub-id pub-id-type="doi">10.1111/j.1468-2958.1978.tb00614.x</pub-id></nlm-citation></ref><ref id="ref36"><label>36</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Rubin</surname><given-names>RB</given-names> </name><name name-style="western"><surname>Martin</surname><given-names>MM</given-names> </name></person-group><article-title>Development of a measure of interpersonal communication competence</article-title><source>Commun Res Rep</source><year>1994</year><month>06</month><volume>11</volume><issue>1</issue><fpage>33</fpage><lpage>44</lpage><pub-id pub-id-type="doi">10.1080/08824099409359938</pub-id></nlm-citation></ref><ref id="ref37"><label>37</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>S&#x00F8;rensen</surname><given-names>K</given-names> </name><name name-style="western"><surname>Van den Broucke</surname><given-names>S</given-names> </name><name name-style="western"><surname>Pelikan</surname><given-names>JM</given-names> </name><etal/></person-group><article-title>Measuring health literacy in populations: illuminating the design and development process of the European Health Literacy Survey Questionnaire (HLS-EU-Q)</article-title><source>BMC Public Health</source><year>2013</year><month>10</month><day>10</day><volume>13</volume><issue>1</issue><fpage>948</fpage><pub-id pub-id-type="doi">10.1186/1471-2458-13-948</pub-id><pub-id pub-id-type="medline">24112855</pub-id></nlm-citation></ref><ref id="ref38"><label>38</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Zhang</surname><given-names>M</given-names> </name><name name-style="western"><surname>Lu</surname><given-names>Z</given-names> </name><name name-style="western"><surname>Song</surname><given-names>C</given-names> </name><name name-style="western"><surname>Ling</surname><given-names>Y</given-names> </name><name name-style="western"><surname>Li</surname><given-names>W</given-names> </name><name name-style="western"><surname>Zuo</surname><given-names>C</given-names> </name></person-group><article-title>Translation and cross-cultural adaptation of the Chinese version of the HLS-EU-Q47</article-title><source>Health Promot Int</source><year>2024</year><month>08</month><day>1</day><volume>39</volume><issue>4</issue><fpage>daae083</fpage><pub-id pub-id-type="doi">10.1093/heapro/daae083</pub-id><pub-id pub-id-type="medline">39058422</pub-id></nlm-citation></ref><ref id="ref39"><label>39</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Lam</surname><given-names>CLK</given-names> </name><name name-style="western"><surname>Yuen</surname><given-names>NYK</given-names> </name><name name-style="western"><surname>Mercer</surname><given-names>SW</given-names> </name><name name-style="western"><surname>Wong</surname><given-names>W</given-names> </name></person-group><article-title>A pilot study on the validity and reliability of the Patient Enablement Instrument (PEI) in a Chinese population</article-title><source>Fam Pract</source><year>2010</year><month>08</month><volume>27</volume><issue>4</issue><fpage>395</fpage><lpage>403</lpage><pub-id pub-id-type="doi">10.1093/fampra/cmq021</pub-id><pub-id pub-id-type="medline">20435665</pub-id></nlm-citation></ref><ref id="ref40"><label>40</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Caserman</surname><given-names>P</given-names> </name><name name-style="western"><surname>Hoffmann</surname><given-names>K</given-names> </name><name name-style="western"><surname>M&#x00FC;ller</surname><given-names>P</given-names> </name><etal/></person-group><article-title>Quality criteria for serious games: serious part, game part, and balance</article-title><source>JMIR Serious Games</source><year>2020</year><month>07</month><day>24</day><volume>8</volume><issue>3</issue><fpage>e19037</fpage><pub-id pub-id-type="doi">10.2196/19037</pub-id><pub-id pub-id-type="medline">32706669</pub-id></nlm-citation></ref><ref id="ref41"><label>41</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Lakens</surname><given-names>D</given-names> </name></person-group><article-title>Calculating and reporting effect sizes to facilitate cumulative science: a practical primer for t-tests and ANOVAs</article-title><source>Front Psychol</source><year>2013</year><month>11</month><day>26</day><volume>4</volume><fpage>863</fpage><pub-id pub-id-type="doi">10.3389/fpsyg.2013.00863</pub-id><pub-id pub-id-type="medline">24324449</pub-id></nlm-citation></ref><ref id="ref42"><label>42</label><nlm-citation citation-type="book"><person-group person-group-type="author"><name name-style="western"><surname>Cohen</surname><given-names>J</given-names> </name></person-group><source>Statistical Power Analysis for the Behavioral Sciences</source><year>2013</year><access-date>2026-07-07</access-date><edition>2</edition><publisher-name>Routledge</publisher-name><fpage>567</fpage><comment><ext-link ext-link-type="uri" xlink:href="https://utstat.toronto.edu/~brunner/oldclass/378f16/readings/CohenPower.pdf">https://utstat.toronto.edu/~brunner/oldclass/378f16/readings/CohenPower.pdf</ext-link></comment></nlm-citation></ref><ref id="ref43"><label>43</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Koivisto</surname><given-names>J</given-names> </name><name name-style="western"><surname>Malik</surname><given-names>A</given-names> </name></person-group><article-title>Gamification for older adults: a systematic literature review</article-title><source>Gerontologist</source><year>2021</year><month>09</month><day>13</day><volume>61</volume><issue>7</issue><fpage>e360</fpage><lpage>e372</lpage><pub-id pub-id-type="doi">10.1093/geront/gnaa047</pub-id><pub-id pub-id-type="medline">32530026</pub-id></nlm-citation></ref><ref id="ref44"><label>44</label><nlm-citation citation-type="report"><article-title>Information technology usage and penetration</article-title><year>2025</year><access-date>2026-07-07</access-date><publisher-name>Census and Statistics Department, The Government of the Hong Kong Special Administrative Region</publisher-name><comment><ext-link ext-link-type="uri" xlink:href="https://www.censtatd.gov.hk/en/EIndexbySubject.html?scode=590&#x0026;pcode=C0000031">https://www.censtatd.gov.hk/en/EIndexbySubject.html?scode=590&#x0026;pcode=C0000031</ext-link></comment></nlm-citation></ref><ref id="ref45"><label>45</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Peters</surname><given-names>R</given-names> </name><name name-style="western"><surname>Ee</surname><given-names>N</given-names> </name><name name-style="western"><surname>Ward</surname><given-names>SA</given-names> </name><etal/></person-group><article-title>Intergenerational programmes bringing together community dwelling non-familial older adults and children: a systematic review</article-title><source>Arch Gerontol Geriatr</source><year>2021</year><volume>94</volume><fpage>104356</fpage><pub-id pub-id-type="doi">10.1016/j.archger.2021.104356</pub-id><pub-id pub-id-type="medline">33567363</pub-id></nlm-citation></ref><ref id="ref46"><label>46</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Miura</surname><given-names>H</given-names> </name><name name-style="western"><surname>Kariyasu</surname><given-names>M</given-names> </name><name name-style="western"><surname>Yamasaki</surname><given-names>K</given-names> </name><name name-style="western"><surname>Sumi</surname><given-names>Y</given-names> </name></person-group><article-title>Physical, mental and social factors affecting self&#x2010;rated verbal communication among elderly individuals</article-title><source>Geriatrics Gerontology Int</source><year>2004</year><month>06</month><volume>4</volume><issue>2</issue><fpage>100</fpage><lpage>104</lpage><pub-id pub-id-type="doi">10.1111/j.1447-0594.2004.00125.x</pub-id></nlm-citation></ref><ref id="ref47"><label>47</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Gauthier</surname><given-names>A</given-names> </name><name name-style="western"><surname>Kato</surname><given-names>PM</given-names> </name><name name-style="western"><surname>Bul</surname><given-names>KCM</given-names> </name><name name-style="western"><surname>Dunwell</surname><given-names>I</given-names> </name><name name-style="western"><surname>Walker-Clarke</surname><given-names>A</given-names> </name><name name-style="western"><surname>Lameras</surname><given-names>P</given-names> </name></person-group><article-title>Board games for health: a systematic literature review and meta-analysis</article-title><source>Games Health J</source><year>2019</year><month>04</month><volume>8</volume><issue>2</issue><fpage>85</fpage><lpage>100</lpage><pub-id pub-id-type="doi">10.1089/g4h.2018.0017</pub-id><pub-id pub-id-type="medline">30256159</pub-id></nlm-citation></ref><ref id="ref48"><label>48</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Corrigan</surname><given-names>T</given-names> </name><name name-style="western"><surname>Mcnamara</surname><given-names>G</given-names> </name><name name-style="western"><surname>O&#x2019;Hara</surname><given-names>J</given-names> </name></person-group><article-title>Intergenerational learning: a valuable learning experience for higher education students</article-title><source>Eurasian J Educ Res</source><year>2013</year><access-date>2026-07-07</access-date><volume>52</volume><fpage>117</fpage><lpage>136</lpage><comment><ext-link ext-link-type="uri" xlink:href="https://www.researchgate.net/publication/266386848_Intergenerational_Learning_A_Valuable_Learning_Experience_for_Higher_Education_Students">https://www.researchgate.net/publication/266386848_Intergenerational_Learning_A_Valuable_Learning_Experience_for_Higher_Education_Students</ext-link></comment></nlm-citation></ref><ref id="ref49"><label>49</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Carstensen</surname><given-names>LL</given-names> </name><name name-style="western"><surname>Hershfield</surname><given-names>HE</given-names> </name></person-group><article-title>Beyond stereotypes: using socioemotional selectivity theory to improve messaging to older adults</article-title><source>Curr Dir Psychol Sci</source><year>2021</year><month>08</month><day>1</day><volume>30</volume><issue>4</issue><fpage>327</fpage><lpage>334</lpage><pub-id pub-id-type="doi">10.1177/09637214211011468</pub-id><pub-id pub-id-type="medline">34366582</pub-id></nlm-citation></ref><ref id="ref50"><label>50</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>White</surname><given-names>BK</given-names> </name><name name-style="western"><surname>Martin</surname><given-names>A</given-names> </name><name name-style="western"><surname>White</surname><given-names>J</given-names> </name></person-group><article-title>Gamification and older adults: opportunities for gamification to support health promotion initiatives for older adults in the context of COVID-19</article-title><source>Lancet Reg Health West Pac</source><year>2023</year><month>06</month><volume>35</volume><fpage>100528</fpage><pub-id pub-id-type="doi">10.1016/j.lanwpc.2022.100528</pub-id><pub-id pub-id-type="medline">35815240</pub-id></nlm-citation></ref><ref id="ref51"><label>51</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Guardabassi</surname><given-names>V</given-names> </name><name name-style="western"><surname>Manoni</surname><given-names>E</given-names> </name><name name-style="western"><surname>Di Massimo</surname><given-names>M</given-names> </name><name name-style="western"><surname>Cirilli</surname><given-names>E</given-names> </name><name name-style="western"><surname>Maranesi</surname><given-names>A</given-names> </name><name name-style="western"><surname>Nicolini</surname><given-names>P</given-names> </name></person-group><article-title>Aging with board games: fostering well-being in the older population</article-title><source>Front Psychol</source><year>2024</year><volume>15</volume><issue>1501111</issue><fpage>1501111</fpage><pub-id pub-id-type="doi">10.3389/fpsyg.2024.1501111</pub-id><pub-id pub-id-type="medline">39624370</pub-id></nlm-citation></ref><ref id="ref52"><label>52</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Sailer</surname><given-names>M</given-names> </name><name name-style="western"><surname>Hense</surname><given-names>JU</given-names> </name><name name-style="western"><surname>Mayr</surname><given-names>SK</given-names> </name><name name-style="western"><surname>Mandl</surname><given-names>H</given-names> </name></person-group><article-title>How gamification motivates: an experimental study of the effects of specific game design elements on psychological need satisfaction</article-title><source>Comput Human Behav</source><year>2017</year><month>04</month><volume>69</volume><fpage>371</fpage><lpage>380</lpage><pub-id pub-id-type="doi">10.1016/j.chb.2016.12.033</pub-id></nlm-citation></ref></ref-list></back></article>